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• W2896584238 abstract "This project details the development of a novel NGS-based T-cell clonality assay, incorporating all four TcR loci. The assay was both analytically and clinically validated. For the former, a series of idealized specimens was used, with combined PCR/Electrophoresis and Sanger Sequencing to confirm NGS-data. The latter validation compared NGS results to the current gold standard for clinical T-cell clonality testing (i.e. the BIOMED primer PCR-based method) on an appropriately-sized minimally-biased sample of hematopathology specimens. In the latter dataset, the patterns of T-cell clonality were also correlated with clinical, pathologic, and outcome data.%%%%M.Sc.%%%%2018-06-21 00:00:00" @default.
• W2896584238 created "2018-10-26" @default.
• W2896584238 creator A5062325950 @default.
• W2896584238 date "2016-06-01" @default.
• W2896584238 modified "2023-09-27" @default.
• W2896584238 title "Design & Validation of a Hybrid-capture Next-generation Sequencing-based T-cell Clonality Assay" @default.
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• W2896584238 hasPublicationYear "2016" @default.
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