Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896588910> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2896588910 abstract "Posterior fossa (PF) recurrences of supratentorial (ST) World Health Organization (WHO) grade II and III gliomas are thought to be rare and to have grim prognoses.This study entailed searching through our database and reviewing the records of patients with grade II and III ST gliomas who developed PF recurrence with no overt secondary gliomatosis or leptomeningeal spread.Of 2266 grade II and III gliomas, 14 fulfilled the inclusion criteria: 5 oligodendrogliomas (O; 1 OII, 4 OIII); 7 astrocytomas (A; 4 AII, 3 AIII); and 2 oligoastrocytomas (OA; both OAIII). The male/female gender ratio was 10/4, and median age at recurrence was 43 years. Two groups were identified. In one group (n=8; 1 AII, 3 AIII, 2 OAIII, 2 OIII), a rapidly growing contrast-enhancing PF mass (6/8) was associated with ST progression, and median survival time after detection was only 6.5 months despite radiotherapy and/or chemotherapy. In the second group (n=6; 3 AII, 1 OII, and 2 OIII), a non-contrast-enhancing (5/6), asymptomatic (5/6), slow-growing PF mass remained isolated, and treatment with radio- or chemotherapy produced objective responses in three patients and durable stabilization in the remaining three. After a median follow-up of 63months, only one patient died due to delayed recurrence of the ST lesion, while the remaining five patients are still alive.Non-contiguous PF relapses of ST grade II and III gliomas are rare. A high-grade ST tumor that is concomitantly progressing appears to be a predictor of poor survival. Conversely, the tumor course may be indolent if the ST lesion is low-grade and non-progressive at the time of PF involvement. The possible mechanism(s) behind this tropism are also discussed." @default.
- W2896588910 created "2018-10-26" @default.
- W2896588910 creator A5037512845 @default.
- W2896588910 creator A5039402966 @default.
- W2896588910 creator A5039803490 @default.
- W2896588910 creator A5041531993 @default.
- W2896588910 creator A5079049447 @default.
- W2896588910 creator A5085404114 @default.
- W2896588910 date "2018-12-01" @default.
- W2896588910 modified "2023-09-25" @default.
- W2896588910 title "Posterior fossa recurrence of WHO grade II and III supratentorial gliomas" @default.
- W2896588910 cites W1987411814 @default.
- W2896588910 cites W2010441622 @default.
- W2896588910 cites W2086585740 @default.
- W2896588910 cites W2098341282 @default.
- W2896588910 cites W2119096087 @default.
- W2896588910 cites W2160382843 @default.
- W2896588910 cites W2162643152 @default.
- W2896588910 cites W3190892510 @default.
- W2896588910 doi "https://doi.org/10.1016/j.neurol.2017.10.018" @default.
- W2896588910 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30314742" @default.
- W2896588910 hasPublicationYear "2018" @default.
- W2896588910 type Work @default.
- W2896588910 sameAs 2896588910 @default.
- W2896588910 citedByCount "0" @default.
- W2896588910 crossrefType "journal-article" @default.
- W2896588910 hasAuthorship W2896588910A5037512845 @default.
- W2896588910 hasAuthorship W2896588910A5039402966 @default.
- W2896588910 hasAuthorship W2896588910A5039803490 @default.
- W2896588910 hasAuthorship W2896588910A5041531993 @default.
- W2896588910 hasAuthorship W2896588910A5079049447 @default.
- W2896588910 hasAuthorship W2896588910A5085404114 @default.
- W2896588910 hasConcept C126322002 @default.
- W2896588910 hasConcept C141071460 @default.
- W2896588910 hasConcept C2776694085 @default.
- W2896588910 hasConcept C2777910003 @default.
- W2896588910 hasConcept C2781156865 @default.
- W2896588910 hasConcept C2993788527 @default.
- W2896588910 hasConcept C509974204 @default.
- W2896588910 hasConcept C71924100 @default.
- W2896588910 hasConceptScore W2896588910C126322002 @default.
- W2896588910 hasConceptScore W2896588910C141071460 @default.
- W2896588910 hasConceptScore W2896588910C2776694085 @default.
- W2896588910 hasConceptScore W2896588910C2777910003 @default.
- W2896588910 hasConceptScore W2896588910C2781156865 @default.
- W2896588910 hasConceptScore W2896588910C2993788527 @default.
- W2896588910 hasConceptScore W2896588910C509974204 @default.
- W2896588910 hasConceptScore W2896588910C71924100 @default.
- W2896588910 hasLocation W28965889101 @default.
- W2896588910 hasLocation W28965889102 @default.
- W2896588910 hasOpenAccess W2896588910 @default.
- W2896588910 hasPrimaryLocation W28965889101 @default.
- W2896588910 hasRelatedWork W1987215768 @default.
- W2896588910 hasRelatedWork W1995188757 @default.
- W2896588910 hasRelatedWork W2016679923 @default.
- W2896588910 hasRelatedWork W2057721052 @default.
- W2896588910 hasRelatedWork W2082239176 @default.
- W2896588910 hasRelatedWork W2103018930 @default.
- W2896588910 hasRelatedWork W2423950151 @default.
- W2896588910 hasRelatedWork W4229900919 @default.
- W2896588910 hasRelatedWork W4240077505 @default.
- W2896588910 hasRelatedWork W4252472287 @default.
- W2896588910 isParatext "false" @default.
- W2896588910 isRetracted "false" @default.
- W2896588910 magId "2896588910" @default.
- W2896588910 workType "article" @default.