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• W2896598858 abstract "CBCT system is a standard and effective method in IGRT, however, it is time-consuming and causes patients to be exposed to an additional dose, meanwhile, it cannot monitor the inter-fractional errors. Catalyst™ is a novel optical surface imaging system for patient positioning and surveillance during radiotherapy. It has some attractive features in radiotherapy for patient positioning tasks, monitoring and gating, however, the application of it is also limited by relative movement of the skin and deepth of tumor. In our study, we compare set-up displacements derived from Catalyst™ to displacements derived from CBCT in order to explore the possibility of using of Catalyst™ to replace CBCT-based IGRT. Set-up displacements from CatalystTM (C-RAD, Uppsala, Sweden) and CBCT were compared for a total of 928 set-ups in 52 patients. Amongst them,15 patients treated in head and neck (groupA), 18 patients treated in thorax (B) and 10 patients treated in abdomen(C), all patients in these 3 groups were fixed with the thermoplastic film. In addition, there are 9 patients treated in abdomen-thorax were fixed with vacuum pad, 5 of them with free breath (D), and the other 4 patients used active breathing control (ABC) (E). Patients were using CBCT at first positioned and then scanned with the CatalystTM , surface data captured by CatalystTM at the first treatment fraction (CSref) was used as main reference for the CatalystTM , while bony structures from the planning CT were used as a reference for the CBCT. As comparison, the patient outline extracted from the planning CT was used as CatalystTM reference (CTref). The displacements detected by the CBCT were also used for comparison. The mean differences(MD) and standard deviation(SD) of 52 patients between the optical surface imaging system and CBCT displacements in 6 dimensions direction were shown in the following table. Compared with CBCT, the CatalystTM system for radiotherapy guided placement in the head and neck region (which are fixed with thermoplastic film) and abdmen–thorax (fixed with vacuum pad and application with deep inhalation breathing holding-ABC) were more accurate (0.70<p<0.85, 0.53<r<0.71), however, in the other regions were less accurate (0.22<p<0.72, 0.34<r<0.56).Abstract TU_39_3286; Table 1. The MD and SD of 5 groups(×±s)(mm/。)Direction GroupLateralLongitudinalVerticalRotationRollPitchA-0.24±3.641.63±5.880.58±3.41-0.11±1.550.05±1.400.10±1.14B0.00±4.080.22±5.570.46±3.04-0.36±1.430.23±1.26-0.10±1.02C0.03±4.014.90±8.070.50±3.46-0.10±1.100.29±1.660.19±1.14D-2.36±5.144.57±7.811.91±4.45-1.45±1.960.50±1.26-0.44±1.09E-0.23±2.340.74±3.56-0.01±2.760.46±2.520.92±1.30-0.17±1.21 Open table in a new tab The CatalystTM system is a good supplement to the CBCT system for accurate set-up of patients. It may substitute the CBCT-based IGRT and reduce CBCT scan frequency in the head and neck region radiation treatment. It potential role in the other regions IGRT needs to be further studied in the future." @default.
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• W2896598858 date "2018-11-01" @default.
• W2896598858 modified "2023-09-26" @default.
• W2896598858 title "A Comparison of Patient Position Displacements from Catalyst™ System and Cone Beam CT Registrations for Treatment" @default.
• W2896598858 doi "https://doi.org/10.1016/j.ijrobp.2018.07.1533" @default.
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