Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896600062> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2896600062 abstract "The analysis of urinary protein composition is an important step in the evaluation and monitoring of kidney diseases. Among the various approaches, the determination of urinary-specific proteins makes it possible to non-invasively detect a preferentially tubular or glomerular injury, to orientate towards a pathological process, to guide the indication of a kidney biopsy, and to follow the evolution of the disease and the effectiveness of a therapy. No study systematically evaluated the performance of urinary-specific proteins for the diagnosis of a renal disease. We conducted this retrospective study to perform an exhaustive analysis of the correlations that may exist between histologically proven kidney disease and the corresponding specific urinary protein composition it in order to evaluate the diagnostic value of each of its components. Urinary concentrations of total protein, albumin, transferrin, alpha1microglobulin, beta2microglobulin, retinol binding protein, and immunoglobulin G were analyzed in more than 500 patients who underwent renal biopsy and concomitant urine specific protein analysis. Our analysis shows that these markers have a limited positive predictive value in this cohort of complex and unselected kidney diseases. In particular, low molecular weight proteins, and especially alpha1microglobulin, are frequently associated with glomerular diseases. We identified transferrin as an independent predictor of minimal changes disese and renal amyloidosis, and beta2microglobulin as an independent predictor of acute tubulointerstitial nephropathy and myelomatous tubulopathy. Finally, we defined the thresholds at which these parameters had excellent negative predictive values." @default.
- W2896600062 created "2018-10-26" @default.
- W2896600062 creator A5025424518 @default.
- W2896600062 creator A5044141185 @default.
- W2896600062 creator A5047627251 @default.
- W2896600062 creator A5073135129 @default.
- W2896600062 creator A5084580268 @default.
- W2896600062 date "2018-05-01" @default.
- W2896600062 modified "2023-09-30" @default.
- W2896600062 title "Relevance of urinary specific protein assay in the diagnosis of kidney diseases" @default.
- W2896600062 doi "https://doi.org/10.1684/abc.2018.1343" @default.
- W2896600062 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29862969" @default.
- W2896600062 hasPublicationYear "2018" @default.
- W2896600062 type Work @default.
- W2896600062 sameAs 2896600062 @default.
- W2896600062 citedByCount "0" @default.
- W2896600062 crossrefType "journal-article" @default.
- W2896600062 hasAuthorship W2896600062A5025424518 @default.
- W2896600062 hasAuthorship W2896600062A5044141185 @default.
- W2896600062 hasAuthorship W2896600062A5047627251 @default.
- W2896600062 hasAuthorship W2896600062A5073135129 @default.
- W2896600062 hasAuthorship W2896600062A5084580268 @default.
- W2896600062 hasConcept C126322002 @default.
- W2896600062 hasConcept C126894567 @default.
- W2896600062 hasConcept C134018914 @default.
- W2896600062 hasConcept C142724271 @default.
- W2896600062 hasConcept C22814914 @default.
- W2896600062 hasConcept C2775934546 @default.
- W2896600062 hasConcept C2776356786 @default.
- W2896600062 hasConcept C2776940978 @default.
- W2896600062 hasConcept C2778653478 @default.
- W2896600062 hasConcept C2779384505 @default.
- W2896600062 hasConcept C2779573558 @default.
- W2896600062 hasConcept C2780091579 @default.
- W2896600062 hasConcept C2781087799 @default.
- W2896600062 hasConcept C2781184683 @default.
- W2896600062 hasConcept C54847362 @default.
- W2896600062 hasConcept C555293320 @default.
- W2896600062 hasConcept C71924100 @default.
- W2896600062 hasConcept C77411442 @default.
- W2896600062 hasConcept C97749175 @default.
- W2896600062 hasConceptScore W2896600062C126322002 @default.
- W2896600062 hasConceptScore W2896600062C126894567 @default.
- W2896600062 hasConceptScore W2896600062C134018914 @default.
- W2896600062 hasConceptScore W2896600062C142724271 @default.
- W2896600062 hasConceptScore W2896600062C22814914 @default.
- W2896600062 hasConceptScore W2896600062C2775934546 @default.
- W2896600062 hasConceptScore W2896600062C2776356786 @default.
- W2896600062 hasConceptScore W2896600062C2776940978 @default.
- W2896600062 hasConceptScore W2896600062C2778653478 @default.
- W2896600062 hasConceptScore W2896600062C2779384505 @default.
- W2896600062 hasConceptScore W2896600062C2779573558 @default.
- W2896600062 hasConceptScore W2896600062C2780091579 @default.
- W2896600062 hasConceptScore W2896600062C2781087799 @default.
- W2896600062 hasConceptScore W2896600062C2781184683 @default.
- W2896600062 hasConceptScore W2896600062C54847362 @default.
- W2896600062 hasConceptScore W2896600062C555293320 @default.
- W2896600062 hasConceptScore W2896600062C71924100 @default.
- W2896600062 hasConceptScore W2896600062C77411442 @default.
- W2896600062 hasConceptScore W2896600062C97749175 @default.
- W2896600062 hasLocation W28966000621 @default.
- W2896600062 hasOpenAccess W2896600062 @default.
- W2896600062 hasPrimaryLocation W28966000621 @default.
- W2896600062 hasRelatedWork W1985980423 @default.
- W2896600062 hasRelatedWork W2020017742 @default.
- W2896600062 hasRelatedWork W2033996898 @default.
- W2896600062 hasRelatedWork W2067009802 @default.
- W2896600062 hasRelatedWork W2069120520 @default.
- W2896600062 hasRelatedWork W2110092653 @default.
- W2896600062 hasRelatedWork W2135432323 @default.
- W2896600062 hasRelatedWork W2148077413 @default.
- W2896600062 hasRelatedWork W2164301446 @default.
- W2896600062 hasRelatedWork W2349898634 @default.
- W2896600062 hasRelatedWork W2377063864 @default.
- W2896600062 hasRelatedWork W2415843075 @default.
- W2896600062 hasRelatedWork W2914577960 @default.
- W2896600062 hasRelatedWork W2992656853 @default.
- W2896600062 hasRelatedWork W3017163160 @default.
- W2896600062 hasRelatedWork W3108711409 @default.
- W2896600062 hasRelatedWork W3165585075 @default.
- W2896600062 hasRelatedWork W3214666799 @default.
- W2896600062 hasRelatedWork W4225995092 @default.
- W2896600062 hasRelatedWork W2182857766 @default.
- W2896600062 isParatext "false" @default.
- W2896600062 isRetracted "false" @default.
- W2896600062 magId "2896600062" @default.
- W2896600062 workType "article" @default.