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- W2896607059 abstract "Atypical antipsychotics have been highlighted in clinical practice due to ability to promote antipsychotic action at recommended doses without producing extrapyramidal symptoms and better efficacy for positive, negative and cognitive symptoms. A quantitative and qualitative research was undertaken with 20 neurologists (NEU) and 10 geriatricians (GER) to explore their prescriptive routine over aripiprazole, olanzapine, risperidone and quetiapine, as well as to evaluate indications versus patient profiles for these drugs. The major diseases for which physicians prescribe atypical antipsychotics are: Dementia (35%: NEU; 70%: GER), Alzheimer's (45%: NEU), Insomnia / sleep disorder (30%; NEU), Depression (70%: GER) and Schizophrenia (40%: GER). With respect to the most appropriate patient profile for each drug: between neurologists and geriatricians, aripiprazole is suitable for: patients with higher purchasing power, who did not respond to previous treatment, treatment of negative symptoms / blunting, mania / hypomania crisis and young patients. Olanzapine is suitable for: patient with normal / lean weight, higher purchasing power, younger, negative symptoms / blunting, failure of previous treatment, with insomnia or sleep disorders. Quetiapine is suitable for: elderly patient, with insomnia / sleep disorders, mild or moderate clinical condition, failure of previous treatment, acute phase of illness and with associated anxiety. In turn, risperidone is suitable for: failure of previous treatment, patient with normal / lean weight, first psychotic episode, elderly patient and with mild or moderate clinical condition. The most commonly prescribed antipsychotics are quetiapine and risperidone and the main reasons are given in Table 1." @default.
- W2896607059 created "2018-10-26" @default.
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- W2896607059 date "2018-07-01" @default.
- W2896607059 modified "2023-10-16" @default.
- W2896607059 title "P2‐568: PRESCRIPTIVE PROFILE OF ATYPICAL ANTIPSYCHOTICS BY BRAZILIAN NEUROLOGISTS AND GERIATRICIANS" @default.
- W2896607059 doi "https://doi.org/10.1016/j.jalz.2018.06.1263" @default.
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