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- W2896622929 abstract "Postherpetic neuralgia (PHN) is the most troublesome side effect of Herpes Zoster (HZ), which mainly affects the elderly and immunocompromised populations. Despite the current advancement of treatments, PHN persists in many individuals influencing their daily activities and reducing their quality of life. Anticonvulsants, antidepressants, topical therapies including lidocaine and capsaicin, and opioids, are the most widely used therapies for the treatment of PHN. These medications come with their adverse effects, so they should be used carefully with the elderly or with patients with significant comorbidities. Other measures like botulinum toxin, nerve blocks, spinal cord stimulation, and radiofrequency have also contributed significantly to the management of PHN. However, the efficacy, safety, and tolerability of these invasive methods need to be carefully monitored when administering them. Early diagnosis and early initiation of treatment can reduce the burden associated with PHN. The zoster vaccine has effectively reduced the incidence of HZ and PHN. In this article, we discuss the treatment options available for the management of PHN, mainly focusing on the efficacy and safety of different therapeutic modalities." @default.
- W2896622929 created "2018-10-26" @default.
- W2896622929 creator A5032624625 @default.
- W2896622929 creator A5040675788 @default.
- W2896622929 date "2018-10-28" @default.
- W2896622929 modified "2023-09-29" @default.
- W2896622929 title "Modalities in managing postherpetic neuralgia" @default.
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- W2896622929 doi "https://doi.org/10.3344/kjp.2018.31.4.235" @default.
- W2896622929 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6177534" @default.
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