Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896627116> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2896627116 abstract "Abstract As a gold-standard technique for DNA methylation analysis, whole-genome bisulfite sequencing (WGBS) helps researchers to study the genome-wide DNA methylation at single-base resolution. However, aligning WGBS reads to the large reference genome is a major computational bottleneck in DNA methylation analysis projects. Although several WGBS aligners have been developed in recent years, it is difficult for them to efficiently process the ever-increasing bisulfite sequencing data. Here we propose BitMapperBS, an ultrafast and memory-efficient aligner that is designed for WGBS reads. To improve the performance of BitMapperBS, we propose various strategies specifically for the challenges that are unique to the WGBS aligners, which are ignored in most existing methods. Our experiments on real and simulated datasets show that BitMapperBS is one order of magnitude faster than the state-of-the-art WGBS aligners, while achieves similar or better sensitivity and precision. BitMapperBS is freely available at https://github.com/chhylp123/BitMapperBS ." @default.
- W2896627116 created "2018-10-26" @default.
- W2896627116 creator A5044987443 @default.
- W2896627116 creator A5091618278 @default.
- W2896627116 date "2018-10-14" @default.
- W2896627116 modified "2023-10-13" @default.
- W2896627116 title "BitMapperBS: a fast and accurate read aligner for whole-genome bisulfite sequencing" @default.
- W2896627116 cites W1534435001 @default.
- W2896627116 cites W2025648894 @default.
- W2896627116 cites W2051465150 @default.
- W2896627116 cites W2088386938 @default.
- W2896627116 cites W2103441770 @default.
- W2896627116 cites W2106889224 @default.
- W2896627116 cites W2128793361 @default.
- W2896627116 cites W2129713651 @default.
- W2896627116 cites W2131374955 @default.
- W2896627116 cites W2149784730 @default.
- W2896627116 cites W2158874082 @default.
- W2896627116 cites W2170551349 @default.
- W2896627116 cites W2175762584 @default.
- W2896627116 cites W2290322184 @default.
- W2896627116 cites W2340615126 @default.
- W2896627116 cites W2487424965 @default.
- W2896627116 cites W2492182665 @default.
- W2896627116 cites W2591635079 @default.
- W2896627116 cites W2604364312 @default.
- W2896627116 cites W2764195238 @default.
- W2896627116 cites W2787816121 @default.
- W2896627116 cites W2792398545 @default.
- W2896627116 cites W2798933487 @default.
- W2896627116 doi "https://doi.org/10.1101/442798" @default.
- W2896627116 hasPublicationYear "2018" @default.
- W2896627116 type Work @default.
- W2896627116 sameAs 2896627116 @default.
- W2896627116 citedByCount "10" @default.
- W2896627116 countsByYear W28966271162020 @default.
- W2896627116 countsByYear W28966271162021 @default.
- W2896627116 countsByYear W28966271162022 @default.
- W2896627116 crossrefType "posted-content" @default.
- W2896627116 hasAuthorship W2896627116A5044987443 @default.
- W2896627116 hasAuthorship W2896627116A5091618278 @default.
- W2896627116 hasBestOaLocation W28966271161 @default.
- W2896627116 hasConcept C104317684 @default.
- W2896627116 hasConcept C141231307 @default.
- W2896627116 hasConcept C149635348 @default.
- W2896627116 hasConcept C150194340 @default.
- W2896627116 hasConcept C189235521 @default.
- W2896627116 hasConcept C190727270 @default.
- W2896627116 hasConcept C2775959680 @default.
- W2896627116 hasConcept C2780513914 @default.
- W2896627116 hasConcept C41008148 @default.
- W2896627116 hasConcept C54355233 @default.
- W2896627116 hasConcept C70721500 @default.
- W2896627116 hasConcept C86803240 @default.
- W2896627116 hasConceptScore W2896627116C104317684 @default.
- W2896627116 hasConceptScore W2896627116C141231307 @default.
- W2896627116 hasConceptScore W2896627116C149635348 @default.
- W2896627116 hasConceptScore W2896627116C150194340 @default.
- W2896627116 hasConceptScore W2896627116C189235521 @default.
- W2896627116 hasConceptScore W2896627116C190727270 @default.
- W2896627116 hasConceptScore W2896627116C2775959680 @default.
- W2896627116 hasConceptScore W2896627116C2780513914 @default.
- W2896627116 hasConceptScore W2896627116C41008148 @default.
- W2896627116 hasConceptScore W2896627116C54355233 @default.
- W2896627116 hasConceptScore W2896627116C70721500 @default.
- W2896627116 hasConceptScore W2896627116C86803240 @default.
- W2896627116 hasLocation W28966271161 @default.
- W2896627116 hasOpenAccess W2896627116 @default.
- W2896627116 hasPrimaryLocation W28966271161 @default.
- W2896627116 hasRelatedWork W1480771059 @default.
- W2896627116 hasRelatedWork W1964177829 @default.
- W2896627116 hasRelatedWork W1981212296 @default.
- W2896627116 hasRelatedWork W2033196363 @default.
- W2896627116 hasRelatedWork W2035236309 @default.
- W2896627116 hasRelatedWork W2167501668 @default.
- W2896627116 hasRelatedWork W2614855875 @default.
- W2896627116 hasRelatedWork W2805216920 @default.
- W2896627116 hasRelatedWork W3159109601 @default.
- W2896627116 hasRelatedWork W4200282989 @default.
- W2896627116 isParatext "false" @default.
- W2896627116 isRetracted "false" @default.
- W2896627116 magId "2896627116" @default.
- W2896627116 workType "article" @default.