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• W2896633771 abstract "Radiation oncology guidelines favor hypofractionated whole breast irradiation (HF-WBI) following breast conserving surgery over more conventional fractionation schemes, but adoption varies worldwide. The purpose of this study is to assess uptake of HF-WFT systematically. Rapid Review of literature published between 1/2008 and 12/2017 were performed using standardized guidelines. Primary databases used were PubMed and Embase. Citation tracking methods were also incorporated. Subject heading and index term searches utilized a combination of the following key words: hypofractionation, fractionation, dose, breast, radiotherapy, radiation, irradiation, neoplasms, breast neoplasm, practice patterns, utilization, standards, quality of health care, economics, adoption, quality, cost, practice, and guideline. Categorization of manuscripts was performed using Rayyan. Papers were included if they reported results of uptake in > 1 institution. Additionally, studies reporting physician practice patters were also included, as were references noted in relevant articles. Papers from single institution experiences, or reporting results of clinical trials, and clinical outcomes were excluded. Eight hundred thirty-two publications were reviewed, 32 of which met inclusion criteria. The included studies originated from Australia, Canada, France, Italy, New Zealand, Pakistan, Spain, Taiwan, United Kingdom, and the United States. Countries with the highest overall adoption include the United Kingdom, Taiwan, Italy, and Canada with 87%, 77%, 76%, and 75% of eligible patients receiving HF-WBI between 2010 and 2015 respectively (Table 1). The country with the lowest adoption was Spain with 29% of eligible patients receiving HF-WBI in 2015. In contrast, the United Kingdom and Canada had the highest rate (50%, 66%) of early adoption of HF-WBI by 2003. In the United States, eligible patients receiving HF-WBI increased from 4-7% to 33-49% between 2004 and 2014. Studies (n=5) reported on surveys of physician practice patterns, in the following countries: Australia, Italy, New Zealand, and the United States. The largest barriers noted in these studies were size of practice, institutional historical bias by practitioners, practitioner interpretations of the literature, and lack of resources.Abstract TU_3_3345; Table 1Hypofractionation by country.CountrySample SizeFacilities SurveysHighest Reported % HypofractionationAustralia/New Zealand588019274%Canada4988775%France406268%Italy19476%Pakistan197330%Spain358282829%Taiwan (Republic of China)204277%United Kingdom5318287%United States47168949% Open table in a new tab There is slow, but increasing uptake of hypofractionation for breast cancer, there remains little reporting in the literature by many countries around the world to assess true uptake. While" @default.
• W2896633771 created "2018-10-26" @default.
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• W2896633771 date "2018-11-01" @default.
• W2896633771 modified "2023-09-27" @default.
• W2896633771 title "Uptake of Whole Breast Hypofractionation: A Rapid Review of the Literature" @default.
• W2896633771 doi "https://doi.org/10.1016/j.ijrobp.2018.07.1591" @default.
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