FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896640710> ?p ?o ?g. }

• W2896640710 endingPage "437" @default.
• W2896640710 startingPage "426" @default.
• W2896640710 abstract "Our study explored the application of methods to generalize randomized controlled trial results to a target population without individual-level data. We compared 4 methods using aggregate data for the target population to generalize results from the international trial, Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER), to a target population of trial-eligible patients in the UK Clinical Practice Research Datalink (CPRD). The gold-standard method used individual data from both the trial and CPRD to predict probabilities of being sampled in the trial and to reweight trial participants to reflect CPRD patient characteristics. Methods 1 and 2 used weighting methods based on simulated individual data or the method of moments, respectively. Method 3 weighted the trial’s subgroup-specific treatment effects to match the distribution of an effect modifier in CPRD. Method 4 calculated the expected absolute benefits in CPRD assuming homogeneous relative treatment effect. Methods based on aggregate data for the target population generally yielded results between the trial and gold-standard estimates. Methods 1 and 2 yielded estimates closest to the gold-standard estimates when continuous effect modifiers were represented as categorical variables. Although individual data or data on joint distributions remains the best approach to generalize trial results, these methods using aggregate data might be useful tools for timely assessment of randomized trial generalizability." @default.
• W2896640710 created "2018-10-26" @default.
• W2896640710 creator A5039914654 @default.
• W2896640710 creator A5040054760 @default.
• W2896640710 creator A5041966893 @default.
• W2896640710 creator A5042519493 @default.
• W2896640710 creator A5043069598 @default.
• W2896640710 creator A5043117381 @default.
• W2896640710 creator A5057522772 @default.
• W2896640710 creator A5065844636 @default.
• W2896640710 date "2018-10-11" @default.
• W2896640710 modified "2023-10-15" @default.
• W2896640710 title "Comparison of Methods to Generalize Randomized Clinical Trial Results Without Individual-Level Data for the Target Population" @default.
• W2896640710 cites W1591419506 @default.
• W2896640710 cites W1755389849 @default.
• W2896640710 cites W1931149717 @default.
• W2896640710 cites W1969298821 @default.
• W2896640710 cites W2055296410 @default.
• W2896640710 cites W2080542957 @default.
• W2896640710 cites W2090369799 @default.
• W2896640710 cites W2092901728 @default.
• W2896640710 cites W2094344282 @default.
• W2896640710 cites W2123846587 @default.
• W2896640710 cites W2131738845 @default.
• W2896640710 cites W2137983259 @default.
• W2896640710 cites W2261839053 @default.
• W2896640710 cites W2519634482 @default.
• W2896640710 cites W2619335752 @default.
• W2896640710 cites W2650689221 @default.
• W2896640710 cites W2745118776 @default.
• W2896640710 cites W2768868661 @default.
• W2896640710 cites W2885514890 @default.
• W2896640710 cites W2951142340 @default.
• W2896640710 cites W3122781290 @default.
• W2896640710 cites W3125357717 @default.
• W2896640710 doi "https://doi.org/10.1093/aje/kwy233" @default.
• W2896640710 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6357813" @default.
• W2896640710 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30312378" @default.
• W2896640710 hasPublicationYear "2018" @default.
• W2896640710 type Work @default.
• W2896640710 sameAs 2896640710 @default.
• W2896640710 citedByCount "17" @default.
• W2896640710 countsByYear W28966407102019 @default.
• W2896640710 countsByYear W28966407102020 @default.
• W2896640710 countsByYear W28966407102021 @default.
• W2896640710 countsByYear W28966407102022 @default.
• W2896640710 countsByYear W28966407102023 @default.
• W2896640710 crossrefType "journal-article" @default.
• W2896640710 hasAuthorship W2896640710A5039914654 @default.
• W2896640710 hasAuthorship W2896640710A5040054760 @default.
• W2896640710 hasAuthorship W2896640710A5041966893 @default.
• W2896640710 hasAuthorship W2896640710A5042519493 @default.
• W2896640710 hasAuthorship W2896640710A5043069598 @default.
• W2896640710 hasAuthorship W2896640710A5043117381 @default.
• W2896640710 hasAuthorship W2896640710A5057522772 @default.
• W2896640710 hasAuthorship W2896640710A5065844636 @default.
• W2896640710 hasBestOaLocation W28966407101 @default.
• W2896640710 hasConcept C105795698 @default.
• W2896640710 hasConcept C126322002 @default.
• W2896640710 hasConcept C126838900 @default.
• W2896640710 hasConcept C149782125 @default.
• W2896640710 hasConcept C168563851 @default.
• W2896640710 hasConcept C183115368 @default.
• W2896640710 hasConcept C27158222 @default.
• W2896640710 hasConcept C2908647359 @default.
• W2896640710 hasConcept C33923547 @default.
• W2896640710 hasConcept C40993552 @default.
• W2896640710 hasConcept C5274069 @default.
• W2896640710 hasConcept C535046627 @default.
• W2896640710 hasConcept C71924100 @default.
• W2896640710 hasConcept C99454951 @default.
• W2896640710 hasConceptScore W2896640710C105795698 @default.
• W2896640710 hasConceptScore W2896640710C126322002 @default.
• W2896640710 hasConceptScore W2896640710C126838900 @default.
• W2896640710 hasConceptScore W2896640710C149782125 @default.
• W2896640710 hasConceptScore W2896640710C168563851 @default.
• W2896640710 hasConceptScore W2896640710C183115368 @default.
• W2896640710 hasConceptScore W2896640710C27158222 @default.
• W2896640710 hasConceptScore W2896640710C2908647359 @default.
• W2896640710 hasConceptScore W2896640710C33923547 @default.
• W2896640710 hasConceptScore W2896640710C40993552 @default.
• W2896640710 hasConceptScore W2896640710C5274069 @default.
• W2896640710 hasConceptScore W2896640710C535046627 @default.
• W2896640710 hasConceptScore W2896640710C71924100 @default.
• W2896640710 hasConceptScore W2896640710C99454951 @default.
• W2896640710 hasFunder F4320332161 @default.
• W2896640710 hasIssue "2" @default.
• W2896640710 hasLocation W28966407101 @default.
• W2896640710 hasLocation W28966407102 @default.
• W2896640710 hasLocation W28966407103 @default.
• W2896640710 hasLocation W28966407104 @default.
• W2896640710 hasLocation W28966407105 @default.
• W2896640710 hasOpenAccess W2896640710 @default.
• W2896640710 hasPrimaryLocation W28966407101 @default.
• W2896640710 hasRelatedWork W2018698423 @default.
• W2896640710 hasRelatedWork W2114938072 @default.
• W2896640710 hasRelatedWork W2415000322 @default.
• W2896640710 hasRelatedWork W2777522569 @default.

• next