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- W2896645008 abstract "In designing of Prodrugs, targeting can be achieved in two ways: site-specified drug delivery and site-specific drug bioactivation. Prodrugs can be designed to target specific enzymes or carriers by considering enzyme-substrate specificity or carrier-substrate specificity in order to overcome various undesirable drug properties. There are certain techniques which are used for tumor targeting such as Antibody Directed Enzyme Prodrug Therapy [ADEPT] Gene-Directed Enzyme Prodrug Therapy [GDEPT], Virus Directed Enzyme Prodrug Therapy [VDEPT] and Gene Prodrug Activation Therapy [GPAT]. Our review focuses on the Prodrugs used in site-specific drug delivery system specially on tumor targeting." @default.
- W2896645008 created "2018-10-26" @default.
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- W2896645008 date "2018-10-23" @default.
- W2896645008 modified "2023-10-14" @default.
- W2896645008 title "Therapeutic Potential of Prodrugs Towards Targeted Drug Delivery" @default.
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- W2896645008 doi "https://doi.org/10.2174/1874104501812010111" @default.
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