FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896659578> ?p ?o ?g. }

• W2896659578 endingPage "e639" @default.
• W2896659578 startingPage "e638" @default.
• W2896659578 abstract "A restrospective study in multicenter was carried out to summary the last 15 years’ experience of Intensity Modulated Radiation Therapy (IMRT) or 3D Conformal Radiotherapy(3D-CRT) combined with brachytherapy and concurrent chemoradiothearpy in advanced cervical cancer in China. A total of 1,962 patients with FIGO stage IB2-IVA cervical cancer from 17 Chinese tertiary hospitals were enrolled in from Dec 2014 to Jan 2000. Inclusion Criteria also included ： 1） with external beam by IMRT or 3D-CRT, 2） with 2D or 3D bracytherapy by tandem and ovoid placed simultaneously, 3) KPS≥60, 4） 18∼70 years old. Overall survival rates(OS), progression-free survival(PFS), local control rates(LC) were analyzed with Kaplan-Meier methods. The effects of treatment techniques and patterns on the prognosis were analyzed with Cox regression and Kaplan-Meier methods. Of the 1,962 patients, 52.04%% patients had FIGO IIB disease and 35.42% patients had FIGO IIIB disease. 95.39% patients had squamous cell carcinoma. VMAT/TOMO, Fix field IMRT(FF-IMRT),3D-CRT used for external beam radiotherapy were 27.62%,34.40%,37.97%. 2D intracavitary， 3D intracavitary combined with or without implant used for brachytherapy were 57.65%,42.35%, and 89.41% patients prescribed with target volume in 3D brachytherapy. Cisplatin weekly chemotherapy was used in 74.57% patients, chemotherapy before and after radiotherapy were 20.69%,18.86%. The median follow-up time was 43.64 months, and the longest follow-up time was 11.2 years. The 3-year and 5-year OS were 86.70%, 80.80%, respectively. The median PFS time was 38.57 months, 3-year and 5-year PFS rates were 80.8%, 77.4%. The 3-year and 5-year LC rate were 93.7%,92.6%, and the median survival time from recurrence was 9.9 months. 3.06% patients had chronic Grade 3-4 gastrointestinal toxicities and 2.90% patients had chronic Grade 3-4 genitourinary toxicities. Stage and pathology were independent prognostic factors, prognostic of adenocarcinoma with stage more than IIA2 was poorer compared to squamous cell carcinoma particularly. In addition, no statistical difference of OS, DFS, LC were found between IMRT and 3D-CRT, and between 2D and 3D brachytherapy. Chemotherapy before radiotherapy was not observed survival advantage significantly (p=0.580). Application of IMRT and 3D-CRT combined combined with brachytherapy and concurrent chemoradiothearpy in advanced cervical cancer had achieved good effect in China. But application of new modes such as IMRT, 3D brachtherapy, chemotherapy before radiotherapy were not observed survival advantage compared to traditional mode." @default.
• W2896659578 created "2018-10-26" @default.
• W2896659578 creator A5000240387 @default.
• W2896659578 creator A5009047738 @default.
• W2896659578 creator A5016394260 @default.
• W2896659578 creator A5016853386 @default.
• W2896659578 creator A5017417518 @default.
• W2896659578 creator A5039784240 @default.
• W2896659578 creator A5046986882 @default.
• W2896659578 creator A5053620278 @default.
• W2896659578 creator A5053683357 @default.
• W2896659578 creator A5056637168 @default.
• W2896659578 creator A5061292048 @default.
• W2896659578 creator A5066037624 @default.
• W2896659578 creator A5079302072 @default.
• W2896659578 creator A5080092242 @default.
• W2896659578 creator A5084123261 @default.
• W2896659578 creator A5086872550 @default.
• W2896659578 creator A5089338603 @default.
• W2896659578 creator A5089884032 @default.
• W2896659578 date "2018-11-01" @default.
• W2896659578 modified "2023-10-18" @default.
• W2896659578 title "Intensity Modulated Radiation Therapy or 3D Conformal Radiation Therapy Combined with Brachytherapy and Concurrent Chemoradiotherapy in Advanced Cervical Cancer: A Retrospective Multicenter Study." @default.
• W2896659578 doi "https://doi.org/10.1016/j.ijrobp.2018.07.1741" @default.
• W2896659578 hasPublicationYear "2018" @default.
• W2896659578 type Work @default.
• W2896659578 sameAs 2896659578 @default.
• W2896659578 citedByCount "0" @default.
• W2896659578 crossrefType "journal-article" @default.
• W2896659578 hasAuthorship W2896659578A5000240387 @default.
• W2896659578 hasAuthorship W2896659578A5009047738 @default.
• W2896659578 hasAuthorship W2896659578A5016394260 @default.
• W2896659578 hasAuthorship W2896659578A5016853386 @default.
• W2896659578 hasAuthorship W2896659578A5017417518 @default.
• W2896659578 hasAuthorship W2896659578A5039784240 @default.
• W2896659578 hasAuthorship W2896659578A5046986882 @default.
• W2896659578 hasAuthorship W2896659578A5053620278 @default.
• W2896659578 hasAuthorship W2896659578A5053683357 @default.
• W2896659578 hasAuthorship W2896659578A5056637168 @default.
• W2896659578 hasAuthorship W2896659578A5061292048 @default.
• W2896659578 hasAuthorship W2896659578A5066037624 @default.
• W2896659578 hasAuthorship W2896659578A5079302072 @default.
• W2896659578 hasAuthorship W2896659578A5080092242 @default.
• W2896659578 hasAuthorship W2896659578A5084123261 @default.
• W2896659578 hasAuthorship W2896659578A5086872550 @default.
• W2896659578 hasAuthorship W2896659578A5089338603 @default.
• W2896659578 hasAuthorship W2896659578A5089884032 @default.
• W2896659578 hasConcept C121608353 @default.
• W2896659578 hasConcept C126322002 @default.
• W2896659578 hasConcept C126838900 @default.
• W2896659578 hasConcept C143998085 @default.
• W2896659578 hasConcept C146357865 @default.
• W2896659578 hasConcept C151730666 @default.
• W2896659578 hasConcept C2775908122 @default.
• W2896659578 hasConcept C2777416452 @default.
• W2896659578 hasConcept C2778220009 @default.
• W2896659578 hasConcept C2778424827 @default.
• W2896659578 hasConcept C2989005 @default.
• W2896659578 hasConcept C509974204 @default.
• W2896659578 hasConcept C71924100 @default.
• W2896659578 hasConcept C86803240 @default.
• W2896659578 hasConceptScore W2896659578C121608353 @default.
• W2896659578 hasConceptScore W2896659578C126322002 @default.
• W2896659578 hasConceptScore W2896659578C126838900 @default.
• W2896659578 hasConceptScore W2896659578C143998085 @default.
• W2896659578 hasConceptScore W2896659578C146357865 @default.
• W2896659578 hasConceptScore W2896659578C151730666 @default.
• W2896659578 hasConceptScore W2896659578C2775908122 @default.
• W2896659578 hasConceptScore W2896659578C2777416452 @default.
• W2896659578 hasConceptScore W2896659578C2778220009 @default.
• W2896659578 hasConceptScore W2896659578C2778424827 @default.
• W2896659578 hasConceptScore W2896659578C2989005 @default.
• W2896659578 hasConceptScore W2896659578C509974204 @default.
• W2896659578 hasConceptScore W2896659578C71924100 @default.
• W2896659578 hasConceptScore W2896659578C86803240 @default.
• W2896659578 hasIssue "3" @default.
• W2896659578 hasLocation W28966595781 @default.
• W2896659578 hasOpenAccess W2896659578 @default.
• W2896659578 hasPrimaryLocation W28966595781 @default.
• W2896659578 hasRelatedWork W2174266008 @default.
• W2896659578 hasRelatedWork W2513916013 @default.
• W2896659578 hasRelatedWork W2942848944 @default.
• W2896659578 hasRelatedWork W2966036943 @default.
• W2896659578 hasRelatedWork W3029213237 @default.
• W2896659578 hasRelatedWork W3031343993 @default.
• W2896659578 hasRelatedWork W4206581437 @default.
• W2896659578 hasRelatedWork W4237106564 @default.
• W2896659578 hasRelatedWork W4245694863 @default.
• W2896659578 hasRelatedWork W4364377845 @default.
• W2896659578 hasVolume "102" @default.
• W2896659578 isParatext "false" @default.
• W2896659578 isRetracted "false" @default.
• W2896659578 magId "2896659578" @default.
• W2896659578 workType "article" @default.