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- W2896664526 endingPage "316" @default.
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- W2896664526 abstract "We report a general, practical, and scalable means of preparing deuterated aldehydes from aromatic and aliphatic carboxylic acids with D2 O as an inexpensive deuterium source. The use of Ph3 P as an O-atom transfer reagent can facilitate the deoxygenation of aromatic acids, while Ph2 POEt is a better O-atom transfer reagent for aliphatic acids. The highly precise deoxygenation of complex carboxylic acids makes this protocol promising for late-stage deoxygenative deuteration of natural product derivatives and pharmaceutical compounds." @default.
- W2896664526 created "2018-10-26" @default.
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- W2896664526 date "2018-11-16" @default.
- W2896664526 modified "2023-10-12" @default.
- W2896664526 title "Deoxygenative Deuteration of Carboxylic Acids with D<sub>2</sub> O" @default.
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- W2896664526 doi "https://doi.org/10.1002/anie.201811522" @default.
- W2896664526 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30352142" @default.
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