Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896672206> ?p ?o ?g. }
- W2896672206 abstract "Abstract Polysaccharides present in plant biomass, such as pectin, are the main carbon source for filamentous fungi. Aspergillus niger naturally secretes pectinases to degrade pectin and utilize the released monomers, mainly D‐galacturonic acid. The transcriptional activator GaaR, the repressor of D‐galacturonic acid utilization GaaX, and the physiological inducer 2‐keto‐3‐deoxy‐L‐galactonate play important roles in the transcriptional regulation of D‐galacturonic acid‐responsive genes, which include the genes encoding pectinases. In this study, we described the mutations found in gaaX and gaaR that enabled constitutive (i.e., inducer‐independent) expression of pectinases by A. niger . Using promoter‐reporter strains (P pgaX ‐ amdS ) and polygalacturonic acid plate assays, we showed that W361R mutation in GaaR results in constitutive production of pectinases. Analysis of subcellular localization of C‐terminally eGFP ‐tagged GaaR/Gaa R W 361R revealed important differences in nuclear accumulation of N‐ versus C‐terminally eGFP ‐tagged GaaR." @default.
- W2896672206 created "2018-10-26" @default.
- W2896672206 creator A5001297004 @default.
- W2896672206 creator A5035576835 @default.
- W2896672206 creator A5048694693 @default.
- W2896672206 creator A5053107746 @default.
- W2896672206 creator A5060119095 @default.
- W2896672206 creator A5072964205 @default.
- W2896672206 creator A5086912284 @default.
- W2896672206 date "2018-10-08" @default.
- W2896672206 modified "2023-10-02" @default.
- W2896672206 title "W361R mutation in GaaR, the regulator of D‐galacturonic acid‐responsive genes, leads to constitutive production of pectinases in<i>Aspergillus niger</i>" @default.
- W2896672206 cites W111143005 @default.
- W2896672206 cites W1984431188 @default.
- W2896672206 cites W1984668713 @default.
- W2896672206 cites W1985393655 @default.
- W2896672206 cites W1993494137 @default.
- W2896672206 cites W2003409774 @default.
- W2896672206 cites W2006373538 @default.
- W2896672206 cites W2009499636 @default.
- W2896672206 cites W2014536167 @default.
- W2896672206 cites W2022395923 @default.
- W2896672206 cites W2050828271 @default.
- W2896672206 cites W2055043387 @default.
- W2896672206 cites W2075946350 @default.
- W2896672206 cites W2096235134 @default.
- W2896672206 cites W2097027136 @default.
- W2896672206 cites W2106728647 @default.
- W2896672206 cites W2115420193 @default.
- W2896672206 cites W2118900513 @default.
- W2896672206 cites W2120814647 @default.
- W2896672206 cites W2121772614 @default.
- W2896672206 cites W2153544371 @default.
- W2896672206 cites W2175879646 @default.
- W2896672206 cites W2198063470 @default.
- W2896672206 cites W2350270487 @default.
- W2896672206 cites W2419885975 @default.
- W2896672206 cites W2551423252 @default.
- W2896672206 cites W2607191494 @default.
- W2896672206 cites W2607303210 @default.
- W2896672206 cites W2625295830 @default.
- W2896672206 cites W2793345208 @default.
- W2896672206 cites W288346875 @default.
- W2896672206 cites W2888407023 @default.
- W2896672206 cites W4238474133 @default.
- W2896672206 cites W843125789 @default.
- W2896672206 cites W927857605 @default.
- W2896672206 doi "https://doi.org/10.1002/mbo3.732" @default.
- W2896672206 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6528562" @default.
- W2896672206 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30298571" @default.
- W2896672206 hasPublicationYear "2018" @default.
- W2896672206 type Work @default.
- W2896672206 sameAs 2896672206 @default.
- W2896672206 citedByCount "10" @default.
- W2896672206 countsByYear W28966722062020 @default.
- W2896672206 countsByYear W28966722062021 @default.
- W2896672206 countsByYear W28966722062022 @default.
- W2896672206 countsByYear W28966722062023 @default.
- W2896672206 crossrefType "journal-article" @default.
- W2896672206 hasAuthorship W2896672206A5001297004 @default.
- W2896672206 hasAuthorship W2896672206A5035576835 @default.
- W2896672206 hasAuthorship W2896672206A5048694693 @default.
- W2896672206 hasAuthorship W2896672206A5053107746 @default.
- W2896672206 hasAuthorship W2896672206A5060119095 @default.
- W2896672206 hasAuthorship W2896672206A5072964205 @default.
- W2896672206 hasAuthorship W2896672206A5086912284 @default.
- W2896672206 hasBestOaLocation W28966722061 @default.
- W2896672206 hasConcept C104317684 @default.
- W2896672206 hasConcept C150194340 @default.
- W2896672206 hasConcept C158448853 @default.
- W2896672206 hasConcept C2225953 @default.
- W2896672206 hasConcept C27153228 @default.
- W2896672206 hasConcept C2775960407 @default.
- W2896672206 hasConcept C36857842 @default.
- W2896672206 hasConcept C55493867 @default.
- W2896672206 hasConcept C86803240 @default.
- W2896672206 hasConceptScore W2896672206C104317684 @default.
- W2896672206 hasConceptScore W2896672206C150194340 @default.
- W2896672206 hasConceptScore W2896672206C158448853 @default.
- W2896672206 hasConceptScore W2896672206C2225953 @default.
- W2896672206 hasConceptScore W2896672206C27153228 @default.
- W2896672206 hasConceptScore W2896672206C2775960407 @default.
- W2896672206 hasConceptScore W2896672206C36857842 @default.
- W2896672206 hasConceptScore W2896672206C55493867 @default.
- W2896672206 hasConceptScore W2896672206C86803240 @default.
- W2896672206 hasFunder F4320322725 @default.
- W2896672206 hasFunder F4320334593 @default.
- W2896672206 hasIssue "5" @default.
- W2896672206 hasLocation W28966722061 @default.
- W2896672206 hasLocation W28966722062 @default.
- W2896672206 hasLocation W28966722063 @default.
- W2896672206 hasLocation W28966722064 @default.
- W2896672206 hasLocation W28966722065 @default.
- W2896672206 hasOpenAccess W2896672206 @default.
- W2896672206 hasPrimaryLocation W28966722061 @default.
- W2896672206 hasRelatedWork W2035731844 @default.
- W2896672206 hasRelatedWork W2069700683 @default.
- W2896672206 hasRelatedWork W2085510328 @default.
- W2896672206 hasRelatedWork W2124349034 @default.
- W2896672206 hasRelatedWork W2163994303 @default.