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- W2896674447 abstract "Near-infrared absorbing dyes are catching people's attention as they are committed to find materials with greater photoacoustic (PA) and photothermal (PT) effect. In this study, a new series of organic π-conjugated discotic derivatives synthesized via [2 + 2] click chemistry were introduced. The PA intensity and PT conversion effect of the derivatives were monitored. It was found that the π-conjugated discotic derivatives had a proper absorption peak and PA intensity by introducing the click regents. Furthermore, the PA intensity remained relatively high, while B12 molecules were embedded in hydrophobic phospholipid bilayer of liposomes (B12⊂L). The application in biological therapy for tumors become possible as the toxicity of B12⊂L was low. What's more, when B12 molecules embedded in poly (N-isopropylacrylamide)-block-poly (2-nitrobenzyl methacrylate) (PNIPAM-b-PNBM) thermosensitive micelles were irradiated by laser, the molecules could take the place of direct temperature stimulus. This work affords us a way to solve the problem in which direct temperature stimulus is inapplicable." @default.
- W2896674447 created "2018-10-26" @default.
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- W2896674447 date "2018-11-16" @default.
- W2896674447 modified "2023-10-17" @default.
- W2896674447 title "The application of small organic π-conjugated discotic derivatives in photoacoustic imaging and photothermal conversion" @default.
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- W2896674447 doi "https://doi.org/10.1088/1361-6528/aaea25" @default.
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