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- W2896685934 abstract "Abstract Recent advances in the genetics of neurologic diseases coupled with improvements in sensitivity and specificity are making genetic testing an increasingly important part of diagnosis and management for neurologists. However, the complex nature of genetic testing, the nuances of multiple result types, and the short- and long-term consequences of genetic diagnoses raise important ethical issues for the clinician. Neurologists must balance the ethical principles of beneficence and nonmaleficence, on the one hand, with patient autonomy on the other hand, when ordering such tests by facilitating shared decision making, carrying out their fiduciary responsibilities to patients, and ensuring that patients have adequate counseling to make informed decisions. This review summarizes ethical issues related to genetic testing for neurologic diseases, with a focus on clinical practice. Informed consent for genetic testing of patients and asymptomatic at-risk family members is discussed. The roles and responsibilities of physicians as genetic counselors are reviewed, including the framing of incidental findings and variants of unknown significance that impact individuals' decisions about whether to pursue genetic testing and what results they wish to know. Disclosure and its consequences for the patient are placed within an ethical framework to permit a better understanding of why genetic testing is different from most other diagnostic testing ordered by physicians. The review ends with clinical vignettes that attempt to place ethical principles into familiar clinical settings involving physicians, patients and their families." @default.
- W2896685934 created "2018-10-26" @default.
- W2896685934 creator A5000351756 @default.
- W2896685934 creator A5032923167 @default.
- W2896685934 date "2018-10-01" @default.
- W2896685934 modified "2023-10-18" @default.
- W2896685934 title "Ethical Considerations in Neurogenetic Testing" @default.
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- W2896685934 cites W175259722 @default.
- W2896685934 cites W1877873625 @default.
- W2896685934 cites W1903612054 @default.
- W2896685934 cites W1925825565 @default.
- W2896685934 cites W1966318276 @default.
- W2896685934 cites W1968949098 @default.
- W2896685934 cites W1969213496 @default.
- W2896685934 cites W1972836127 @default.
- W2896685934 cites W1980477780 @default.
- W2896685934 cites W1986549431 @default.
- W2896685934 cites W1990845364 @default.
- W2896685934 cites W1995261044 @default.
- W2896685934 cites W2001020014 @default.
- W2896685934 cites W2009610061 @default.
- W2896685934 cites W2014276035 @default.
- W2896685934 cites W2014977309 @default.
- W2896685934 cites W2015037203 @default.
- W2896685934 cites W2018600945 @default.
- W2896685934 cites W2023011946 @default.
- W2896685934 cites W2035895733 @default.
- W2896685934 cites W2036362108 @default.
- W2896685934 cites W2046209489 @default.
- W2896685934 cites W2058285984 @default.
- W2896685934 cites W2058723245 @default.
- W2896685934 cites W2063091609 @default.
- W2896685934 cites W2063127941 @default.
- W2896685934 cites W2067108324 @default.
- W2896685934 cites W2074726646 @default.
- W2896685934 cites W2076268719 @default.
- W2896685934 cites W2077212561 @default.
- W2896685934 cites W2083633251 @default.
- W2896685934 cites W2092293921 @default.
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- W2896685934 cites W2123146946 @default.
- W2896685934 cites W2123423334 @default.
- W2896685934 cites W2125360737 @default.
- W2896685934 cites W2127237723 @default.
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- W2896685934 cites W2150656456 @default.
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- W2896685934 cites W2153168932 @default.
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- W2896685934 cites W2163499486 @default.
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- W2896685934 cites W2546834208 @default.
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- W2896685934 doi "https://doi.org/10.1055/s-0038-1667382" @default.
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