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- W2896692972 abstract "We report a series of CN bridged coumarin-thiazolidine-2,4-dione derivatives 3(a–q). These compounds have been synthesized under both conventional as well as microwave irradiation techniques. The synthesized compounds were characterized by spectral and elemental analyses. The computational study performed for targeted compounds and results obtained were mimicking the potent bio-molecules. All the newly synthesized compounds were screened for their in vitro anti-microbial and anti-inflammatory activities and have shown promising results. In vitro Anti-microbial activity of compounds (3a) and (3i) was found to be most active with bacterial and fungal strains. The compound (3i) shows best anti-inflammatory activity with IC50 of 43.26 µg/mL against protein denaturation." @default.
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- W2896692972 date "2018-12-01" @default.
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- W2896692972 title "Synthesis, molecular docking studies and biological evaluation of potent coumarin-thiazolidinone hybrids: An approach to microwave synthesis" @default.
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- W2896692972 doi "https://doi.org/10.1016/j.cdc.2018.10.002" @default.
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