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- W2896694325 abstract "Telomere length (TL), telomerase activity (TA), and plasma amyloid-β (Aβ) levels have emerged as possible predictors of cognitive decline and dementia.To assess the: 1) effects of two 12-week relaxation programs on TL, TA, and Aβ levels in adults with subjective cognitive decline; and 2) relationship of biomarker changes to those in cognitive function, psychosocial status, and quality of life (QOL).Participants were randomized to a 12-week Kirtan Kriya meditation (KK) or music listening (ML) program and asked to practice 12 minutes/day. Plasma Aβ(38/40/42) and peripheral blood mononuclear cell TL and TA were measured at baseline and 3 months. Cognition, stress, sleep, mood, and QOL were assessed at baseline, 3 months, and 6 months.Baseline blood samples were available for 53 participants (25 KK, 28 ML). The KK group showed significantly greater increases in Aβ40 than the ML group. TA rose in both groups, although increases were significant only among those with higher practice adherence and lower baseline TA. Changes in both TL and TA varied by their baseline values, with greater increases among participants with values ≤50th percentile (ps-interaction <0.006). Both groups improved in cognitive and psychosocial status (ps ≤0.05), with improvements in stress, mood, and QOL greater in the KK group. Rising Aβ levels were correlated with gains in cognitive function, mood, sleep, and QOL at both 3 and 6 months, associations that were particularly pronounced in the KK group. Increases in TL and TA were also correlated with improvements in certain cognitive and psychosocial measures.Practice of simple mind-body therapies may alter plasma Aβ levels, TL, and TA. Biomarker increases were associated with improvements in cognitive function, sleep, mood, and QOL, suggesting potential functional relationships." @default.
- W2896694325 created "2018-10-26" @default.
- W2896694325 creator A5002332204 @default.
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- W2896694325 date "2018-11-23" @default.
- W2896694325 modified "2023-10-16" @default.
- W2896694325 title "Effects of Meditation and Music-Listening on Blood Biomarkers of Cellular Aging and Alzheimer’s Disease in Adults with Subjective Cognitive Decline: An Exploratory Randomized Clinical Trial" @default.
- W2896694325 cites W1551333599 @default.
- W2896694325 cites W1587269472 @default.
- W2896694325 cites W1595929227 @default.
- W2896694325 cites W1682388509 @default.
- W2896694325 cites W1718786689 @default.
- W2896694325 cites W1733523167 @default.
- W2896694325 cites W1767010801 @default.
- W2896694325 cites W1922949753 @default.
- W2896694325 cites W1969262978 @default.
- W2896694325 cites W1972454857 @default.
- W2896694325 cites W1977919599 @default.
- W2896694325 cites W1978420618 @default.
- W2896694325 cites W1978599499 @default.
- W2896694325 cites W1983263771 @default.
- W2896694325 cites W1985879372 @default.
- W2896694325 cites W1988104043 @default.
- W2896694325 cites W1989294424 @default.
- W2896694325 cites W1990793436 @default.
- W2896694325 cites W1992310790 @default.
- W2896694325 cites W1992999217 @default.
- W2896694325 cites W1993467061 @default.
- W2896694325 cites W1994579861 @default.
- W2896694325 cites W1995779519 @default.
- W2896694325 cites W1996053420 @default.
- W2896694325 cites W1996299251 @default.
- W2896694325 cites W1997224430 @default.
- W2896694325 cites W1997457117 @default.
- W2896694325 cites W1998355082 @default.
- W2896694325 cites W2000555003 @default.
- W2896694325 cites W2004760320 @default.
- W2896694325 cites W2005355670 @default.
- W2896694325 cites W2006114008 @default.
- W2896694325 cites W2012298899 @default.
- W2896694325 cites W2013078308 @default.
- W2896694325 cites W2015484447 @default.
- W2896694325 cites W2015858222 @default.
- W2896694325 cites W2017152382 @default.
- W2896694325 cites W2019244067 @default.
- W2896694325 cites W2019671076 @default.
- W2896694325 cites W2023046510 @default.
- W2896694325 cites W2024674966 @default.
- W2896694325 cites W2028911700 @default.
- W2896694325 cites W2029150524 @default.
- W2896694325 cites W2030536163 @default.
- W2896694325 cites W2031002692 @default.
- W2896694325 cites W2034502763 @default.
- W2896694325 cites W2035437757 @default.
- W2896694325 cites W2037403969 @default.
- W2896694325 cites W2038793808 @default.
- W2896694325 cites W2042332326 @default.
- W2896694325 cites W2046059051 @default.
- W2896694325 cites W2058173549 @default.
- W2896694325 cites W2059978287 @default.
- W2896694325 cites W2060754339 @default.
- W2896694325 cites W2062395030 @default.
- W2896694325 cites W2064156568 @default.
- W2896694325 cites W2064842257 @default.
- W2896694325 cites W2065406720 @default.
- W2896694325 cites W2066752981 @default.
- W2896694325 cites W2067724949 @default.
- W2896694325 cites W2067960064 @default.
- W2896694325 cites W2077680376 @default.
- W2896694325 cites W2078184061 @default.
- W2896694325 cites W2079493264 @default.
- W2896694325 cites W2081625950 @default.
- W2896694325 cites W2083337622 @default.
- W2896694325 cites W2088823099 @default.
- W2896694325 cites W2088868199 @default.
- W2896694325 cites W2090839303 @default.
- W2896694325 cites W2093473156 @default.
- W2896694325 cites W2094931894 @default.
- W2896694325 cites W2096369813 @default.
- W2896694325 cites W2096485847 @default.
- W2896694325 cites W2097529540 @default.
- W2896694325 cites W2099145543 @default.
- W2896694325 cites W2099655369 @default.
- W2896694325 cites W2101932434 @default.
- W2896694325 cites W2102320314 @default.
- W2896694325 cites W2103209254 @default.
- W2896694325 cites W2107537187 @default.
- W2896694325 cites W2108953512 @default.
- W2896694325 cites W2116787187 @default.
- W2896694325 cites W2117047219 @default.
- W2896694325 cites W211905087 @default.