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- W2896703905 abstract "Fe(OTf)2 has been found to be an efficient catalyst for the Oxa-Pictet–Spengler cyclization reaction leading to isochromans. A series of substituted isochromans were obtained with good to excellent isolated yields by coupling β-arylethanols with aldehydes or ketals under the catalysis of 1 mol% of Fe(OTf)2 at 70 °C. Using a cheap, less-toxic catalyst with water as the only byproduct, this iron-catalyzed Oxa-Pictet–Spengler reaction can be considered environmentally-friendly and atom-economic." @default.
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- W2896703905 date "2018-12-01" @default.
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- W2896703905 title "Synthesis of isochromans via Fe(OTf)2-catalyzed Oxa-Pictet–Spengler cyclization" @default.
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- W2896703905 doi "https://doi.org/10.1016/j.tet.2018.10.028" @default.
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