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- W2896715693 abstract "Abstract A metal-free and solvent free click-chemistry procedure has been revealed for the synthesis of 4-trifluoroacetyl-1,2,3-triazoles from corresponding azides and alkyne with high yield and selectivity. The pure products could be easily obtained via crystallization of the reaction mixture (standing for 1 day). Among the 4-trifluoroacetyl-1,2,3-triazoles, 3ba showed the best anticancer activity against HepG2 cell with IC50 of 0.0267 μmol/ml. This method has the advantages of less pollution, low cost, simple treatment and more efficiency." @default.
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- W2896715693 date "2018-12-01" @default.
- W2896715693 modified "2023-10-16" @default.
- W2896715693 title "Study on the green click-chemistry synthesis of 4-trifluoroacetyl-1,2,3-triazoles" @default.
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- W2896715693 doi "https://doi.org/10.1016/j.tet.2018.10.026" @default.
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