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- W2896727507 abstract "Here we report the synthesis and biological activity of new 5'-norcarbocyclic derivatives of bicyclic pyrrolo- and furano[2,3-d]pyrimidines with different substituents in the heterocyclic ring. Lead compound 3i, containing 6-pentylphenyl substituent, displays inhibitory activity with respect to a number of tumor cells with a moderate selectivity index value. Compound 3i induces cell death by the apoptosis pathway with the dissipation of mitochondrial potential." @default.
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- W2896727507 date "2018-10-16" @default.
- W2896727507 modified "2023-10-15" @default.
- W2896727507 title "Novel 5′-Norcarbocyclic Derivatives of Bicyclic Pyrrolo- and Furano[2,3-d]Pyrimidine Nucleosides" @default.
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- W2896727507 doi "https://doi.org/10.3390/molecules23102654" @default.
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