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- W2896746492 abstract "Background: The risk of stroke in patients with atrial fibrillation (AF) is reduced with oral anticoagulation therapy (OAT). On the other hand, OAT with warfarin increases the risk of intracranial hemorrhage (ICH). In this nationwide registry study we evaluated the association between the quality of warfarin therapy and the risk of ICH. Methods: FinWAF is a registry study of 54568 unselected AF patients (31172 prevalent and 23396 new warfarin users) by linking data from several Finnish nationwide registries through the civil registration number. Crude incidence rates of ICH among patients with various time in therapeutic range (TTR) levels were analyzed. TTR was assessed with the Rosendaal method and analyzed with a continuous calculation window of 60 days. Hazard ratios (HR) for ICH were adjusted for age, gender, congestive heart failure, hypertension, diabetes, previous stroke, transient ischemic attack, vascular disease, hospitalization and renal function. Results: The mean follow-up time was 3.2 ± 1.6..." @default.
- W2896746492 created "2018-10-26" @default.
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- W2896746492 date "2016-11-11" @default.
- W2896746492 modified "2023-09-23" @default.
- W2896746492 title "Abstract 16593: Risk of Intracranial Hemorrhage During Warfarin Therapy in Patients With Atrial Fibrillation - Insights From the FinWAF Registry" @default.
- W2896746492 hasPublicationYear "2016" @default.
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