FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896753413> ?p ?o ?g. }

• W2896753413 endingPage "283" @default.
• W2896753413 startingPage "272" @default.
• W2896753413 abstract "India witnessed dengue outbreaks during 2017 in different parts with more than 180000 cases. There is no data on the serotypes/genotypes of dengue virus (DENV) associated with the 2017 outbreak season. The present study investigated DENV circulating in Pune and Nashik regions of Maharashtra, Western India at molecular level. IgM negative samples that were collected before 6th post onset days of illness were tested for DENV RNA and serotyped by real time RT-PCR based methods. Representative samples of each serotype were processed for virus isolation and envelope (E) gene sequencing. Among the 472 samples tested for DENV serotypes from Nashik, DENV-1 was observed in 36.2%, DENV-2 in 12.9%, DENV-3 in 35.4%, DENV-4 in 8.0%, and multiple serotypes in 7.4% of the samples respectively. In Pune region, among the 109 samples tested for DENV serotypes, DENV-1 was observed in 27.5%, DENV-2 in 11.0%, DENV-3 in 52.3%, DENV-4 in 4.6%, and multiple serotypes in 4.6% of the samples respectively. Comparison of serotype distribution from 2009 to 2017 from the Pune region revealed the emergence of DENV-3 as the dominant serotype followed by DENV-1 in 2017. In the Nashik region, both DENV-1 and DENV-3 were predominant in 2017. Phylogenetic analyses revealed co-circulation of American African (AM/AF) and Asian genotypes of DENV-1. DENV-1 Asian genotype was detected for the first time in the region. No genotype changes were observed for DENV-2 (cosmopolitan genotype), DENV-3 (genotype III) and DENV-4 (genotype I). For DENV-3, a unique amino acid substitution (I380T) was observed in the domain III of E protein of 2017 isolates and was not observed in earlier DENV-3 genotype III isolates. To conclude, the results suggest the emergence of DENV-1 with circulation of both Asian and AM/AF genotypes and DENV-3 with unique amino acid substitutions in Pune and Nashik regions. The study underscores the need for continuous molecular monitoring at a large scale to detect the changes in DENV serotypes/genotypes that might have implications for earlier prediction of dengue outbreaks and designing dengue vaccines and predicting its efficacy." @default.
• W2896753413 created "2018-10-26" @default.
• W2896753413 creator A5002287372 @default.
• W2896753413 creator A5034723182 @default.
• W2896753413 creator A5042111086 @default.
• W2896753413 creator A5045775973 @default.
• W2896753413 creator A5064488562 @default.
• W2896753413 creator A5070047796 @default.
• W2896753413 creator A5077128931 @default.
• W2896753413 creator A5077773584 @default.
• W2896753413 date "2018-12-01" @default.
• W2896753413 modified "2023-10-16" @default.
• W2896753413 title "Emergence of dengue virus type 1 and type 3 as dominant serotypes during 2017 in Pune and Nashik regions of Maharashtra, Western India" @default.
• W2896753413 cites W1970295487 @default.
• W2896753413 cites W1973667633 @default.
• W2896753413 cites W1980752128 @default.
• W2896753413 cites W1988109653 @default.
• W2896753413 cites W2028079124 @default.
• W2896753413 cites W2028924991 @default.
• W2896753413 cites W2069331412 @default.
• W2896753413 cites W2069531203 @default.
• W2896753413 cites W2080655727 @default.
• W2896753413 cites W2091181646 @default.
• W2896753413 cites W2095886196 @default.
• W2896753413 cites W2097959479 @default.
• W2896753413 cites W2123134819 @default.
• W2896753413 cites W2139881589 @default.
• W2896753413 cites W2141581949 @default.
• W2896753413 cites W2143119188 @default.
• W2896753413 cites W2163354255 @default.
• W2896753413 cites W2163525302 @default.
• W2896753413 cites W2171126517 @default.
• W2896753413 cites W2188486987 @default.
• W2896753413 cites W2301575287 @default.
• W2896753413 cites W2730619833 @default.
• W2896753413 cites W2734627414 @default.
• W2896753413 cites W2748416302 @default.
• W2896753413 cites W2790164653 @default.
• W2896753413 cites W4206339719 @default.
• W2896753413 doi "https://doi.org/10.1016/j.meegid.2018.10.016" @default.
• W2896753413 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30366083" @default.
• W2896753413 hasPublicationYear "2018" @default.
• W2896753413 type Work @default.
• W2896753413 sameAs 2896753413 @default.
• W2896753413 citedByCount "12" @default.
• W2896753413 countsByYear W28967534132019 @default.
• W2896753413 countsByYear W28967534132020 @default.
• W2896753413 countsByYear W28967534132021 @default.
• W2896753413 countsByYear W28967534132023 @default.
• W2896753413 crossrefType "journal-article" @default.
• W2896753413 hasAuthorship W2896753413A5002287372 @default.
• W2896753413 hasAuthorship W2896753413A5034723182 @default.
• W2896753413 hasAuthorship W2896753413A5042111086 @default.
• W2896753413 hasAuthorship W2896753413A5045775973 @default.
• W2896753413 hasAuthorship W2896753413A5064488562 @default.
• W2896753413 hasAuthorship W2896753413A5070047796 @default.
• W2896753413 hasAuthorship W2896753413A5077128931 @default.
• W2896753413 hasAuthorship W2896753413A5077773584 @default.
• W2896753413 hasConcept C10389963 @default.
• W2896753413 hasConcept C104317684 @default.
• W2896753413 hasConcept C116675565 @default.
• W2896753413 hasConcept C135763542 @default.
• W2896753413 hasConcept C159047783 @default.
• W2896753413 hasConcept C2779635636 @default.
• W2896753413 hasConcept C533803919 @default.
• W2896753413 hasConcept C54355233 @default.
• W2896753413 hasConcept C86803240 @default.
• W2896753413 hasConceptScore W2896753413C10389963 @default.
• W2896753413 hasConceptScore W2896753413C104317684 @default.
• W2896753413 hasConceptScore W2896753413C116675565 @default.
• W2896753413 hasConceptScore W2896753413C135763542 @default.
• W2896753413 hasConceptScore W2896753413C159047783 @default.
• W2896753413 hasConceptScore W2896753413C2779635636 @default.
• W2896753413 hasConceptScore W2896753413C533803919 @default.
• W2896753413 hasConceptScore W2896753413C54355233 @default.
• W2896753413 hasConceptScore W2896753413C86803240 @default.
• W2896753413 hasLocation W28967534131 @default.
• W2896753413 hasLocation W28967534132 @default.
• W2896753413 hasOpenAccess W2896753413 @default.
• W2896753413 hasPrimaryLocation W28967534131 @default.
• W2896753413 hasRelatedWork W1971409853 @default.
• W2896753413 hasRelatedWork W2008026220 @default.
• W2896753413 hasRelatedWork W2051134904 @default.
• W2896753413 hasRelatedWork W2131109504 @default.
• W2896753413 hasRelatedWork W2158732944 @default.
• W2896753413 hasRelatedWork W2289986357 @default.
• W2896753413 hasRelatedWork W2308586264 @default.
• W2896753413 hasRelatedWork W2342183947 @default.
• W2896753413 hasRelatedWork W3097575184 @default.
• W2896753413 hasRelatedWork W3098921675 @default.
• W2896753413 hasVolume "66" @default.
• W2896753413 isParatext "false" @default.
• W2896753413 isRetracted "false" @default.
• W2896753413 magId "2896753413" @default.
• W2896753413 workType "article" @default.