Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896761967> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2896761967 abstract "Background ABN immunoglobulin (Ig) guidelines advise routine FBC and U and E monitoring with every treatment episode and screening for IgA deficiency. Aims We audited compliance in inflammatory neuropathy patients on longterm treatment in two UK Neurology departments. We looked for evidence of clinically relevant haematological or AKI Ig-related events. Methods Data was collected from Nov 2015 to Nov 2017. Accepted definitions for clinically and/or biochemically significant haemolysis, neutropenia, thrombocytopenia and AKI were used. Results 1919 treatment episodes in 90 patients were analysed. Mean age (SD)=57.6 (14.4)years, 69.1% male, 74% CIDP (26% MMN), 94% IVIg (6% SCIg). Mean dose=1.57 (0.74) g/kg/month or 97.1 (37.3) g/infusion. No clinically significant episodes of haemolysis, neutropenia, thrombocytopenia or AKI occurred in relation to Ig treatment. An asymptomatic drop of >10 g/L Hb occurred in 68/1919 episodes in 38 individuals (3.5%); mean reduction 17.7 g/L, lowest Hb 99 g/L. Two patients with CRF (stage 3) received 28 (IV) and 104 (SC) infusions respectively without impact on eGFR. Two individuals with relative IgA deficiency (0.38 g/L, 0.4 g/L) received 16 infusions over 1.5 years without complications. Conclusions No clinically significant Ig-related events were identified in this representative cohort. We suggest annual screening or clinically indicated testing as safe and more appropriate in longterm IVIg use." @default.
- W2896761967 created "2018-10-26" @default.
- W2896761967 creator A5000546647 @default.
- W2896761967 creator A5001878666 @default.
- W2896761967 creator A5001906933 @default.
- W2896761967 creator A5037350756 @default.
- W2896761967 creator A5058002592 @default.
- W2896761967 creator A5069223297 @default.
- W2896761967 creator A5071639906 @default.
- W2896761967 creator A5074064703 @default.
- W2896761967 creator A5076573219 @default.
- W2896761967 creator A5080922438 @default.
- W2896761967 date "2018-09-13" @default.
- W2896761967 modified "2023-09-27" @default.
- W2896761967 title "WED 241 Clinical relevance of regular blood monitoring in IG treatment" @default.
- W2896761967 doi "https://doi.org/10.1136/jnnp-2018-abn.121" @default.
- W2896761967 hasPublicationYear "2018" @default.
- W2896761967 type Work @default.
- W2896761967 sameAs 2896761967 @default.
- W2896761967 citedByCount "1" @default.
- W2896761967 countsByYear W28967619672020 @default.
- W2896761967 crossrefType "journal-article" @default.
- W2896761967 hasAuthorship W2896761967A5000546647 @default.
- W2896761967 hasAuthorship W2896761967A5001878666 @default.
- W2896761967 hasAuthorship W2896761967A5001906933 @default.
- W2896761967 hasAuthorship W2896761967A5037350756 @default.
- W2896761967 hasAuthorship W2896761967A5058002592 @default.
- W2896761967 hasAuthorship W2896761967A5069223297 @default.
- W2896761967 hasAuthorship W2896761967A5071639906 @default.
- W2896761967 hasAuthorship W2896761967A5074064703 @default.
- W2896761967 hasAuthorship W2896761967A5076573219 @default.
- W2896761967 hasAuthorship W2896761967A5080922438 @default.
- W2896761967 hasConcept C126322002 @default.
- W2896761967 hasConcept C187212893 @default.
- W2896761967 hasConcept C203014093 @default.
- W2896761967 hasConcept C2776694085 @default.
- W2896761967 hasConcept C2777063308 @default.
- W2896761967 hasConcept C2777910003 @default.
- W2896761967 hasConcept C2780873365 @default.
- W2896761967 hasConcept C2910801743 @default.
- W2896761967 hasConcept C71924100 @default.
- W2896761967 hasConcept C72563966 @default.
- W2896761967 hasConcept C90924648 @default.
- W2896761967 hasConceptScore W2896761967C126322002 @default.
- W2896761967 hasConceptScore W2896761967C187212893 @default.
- W2896761967 hasConceptScore W2896761967C203014093 @default.
- W2896761967 hasConceptScore W2896761967C2776694085 @default.
- W2896761967 hasConceptScore W2896761967C2777063308 @default.
- W2896761967 hasConceptScore W2896761967C2777910003 @default.
- W2896761967 hasConceptScore W2896761967C2780873365 @default.
- W2896761967 hasConceptScore W2896761967C2910801743 @default.
- W2896761967 hasConceptScore W2896761967C71924100 @default.
- W2896761967 hasConceptScore W2896761967C72563966 @default.
- W2896761967 hasConceptScore W2896761967C90924648 @default.
- W2896761967 hasLocation W28967619671 @default.
- W2896761967 hasOpenAccess W2896761967 @default.
- W2896761967 hasPrimaryLocation W28967619671 @default.
- W2896761967 hasRelatedWork W1591506473 @default.
- W2896761967 hasRelatedWork W2011296554 @default.
- W2896761967 hasRelatedWork W2076684456 @default.
- W2896761967 hasRelatedWork W2086851718 @default.
- W2896761967 hasRelatedWork W2171557592 @default.
- W2896761967 hasRelatedWork W2397993193 @default.
- W2896761967 hasRelatedWork W2432027882 @default.
- W2896761967 hasRelatedWork W3112047706 @default.
- W2896761967 hasRelatedWork W3185434855 @default.
- W2896761967 hasRelatedWork W3023875988 @default.
- W2896761967 isParatext "false" @default.
- W2896761967 isRetracted "false" @default.
- W2896761967 magId "2896761967" @default.
- W2896761967 workType "article" @default.