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- W2896765191 abstract "Cell–ECM interactions (ECM=extracellular matrix) can keep the cells alive through the activation of intracellular survival signaling pathways. When cells are detached from ECM stroma, the cells enter an attachment-deprived state, which is devoid of extracellular signals that trigger the activation of survival signaling pathways. Therefore, single cells in the detached state eventually undergo anoikis, a type of cell death induced by an attachment-deprived state. Cell encapsulation can provide a signaling que for the cells in an attachment-deprived state to activate survival signaling pathways. Depending on the purpose of application, cells are encapsulated in their single-cellular or multicellular states. The Minireview by E. Lee et al. on page 15725 ff. summarizes the current research strategies of cell encapsulation in the perspective for future applications." @default.
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- W2896765191 date "2018-10-22" @default.
- W2896765191 modified "2023-09-27" @default.
- W2896765191 title "Frontispiece: Cell-Surface Engineering for Advanced Cell Therapy" @default.
- W2896765191 doi "https://doi.org/10.1002/chem.201885963" @default.
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