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• W2896767824 abstract "Fetal isolated ventricular asymmetry (IVA) is a relatively common finding in pregnancy, but data regarding its effect on neurodevelopmental outcome are scarce and based on studies using the ultrasound modality. The purpose of this study was to assess the outcomes of IVAs in a magnetic resonance imaging (MRI) based study. A historical cohort study from a single tertiary institution. Cases referred to fetal brain MRI as part of the investigation of IVA without ventriculomegaly (≤10 mm), identified during routine ultrasound examinations, were assessed for possible inclusion. Asymmetry was defined as a difference of ≥2 mm between the two lateral ventricles. Cases with additional central nervous system (CNS) or non-CNS findings on US or MRI were excluded. The study group was compared to a control group of cases with normal pregnancy follow-up exams without IVA. Children were assessed at ages 13 to 74 months using the Vineland Adaptive Behaviour Scales (VABS), a structured parent interview assessing four different scales of performance: communication, daily living skills, socialisation, and motor skills. Forty-three cases were included in the study group and 94 in the control group. VABS scores were within normal range. There was no significant difference in composite VABS score between the study and control groups (106.5 vs 108.0, respectively; p = 0.454). Within the different components of the VABS score, the social skills score was significantly lower in the study group compared to the control group (100.4 vs 106.3, respectively; p = 0.009). When comparing cases of IVA to controls matched for gender and children's age during VABS there was no significant difference in the composite VABS score (109.6 in study group vs 107.8 in control group; p = 0.690), or any of its components. None of the cases with IVA needed medical evaluation due to abnormal neurodevelopment after birth. In cases of IVA without ventriculomegaly on MRI, neurodevelopmental test scores were normal and did not differ from cases without IVA. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
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• W2896767824 date "2018-10-01" @default.
• W2896767824 modified "2023-10-07" @default.
• W2896767824 title "P11.02: Neurodevelopmental outcome of fetuses with isolated ventricular asymmetry without dilation" @default.
• W2896767824 doi "https://doi.org/10.1002/uog.19696" @default.
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