Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896770208> ?p ?o ?g. }
- W2896770208 endingPage "1118" @default.
- W2896770208 startingPage "1108" @default.
- W2896770208 abstract "From biogenesis to degradation, mRNA goes through diverse types of regulation and interaction with other biomolecules. Uneven distribution of mRNA transcripts and the diverse isoforms and modifications of mRNA make us wonder how cells manage the complexity and keep the functional integrity for the normal development of cells and organisms. Single-molecule microscopy tools have expanded the scope of RNA research with unprecedented spatiotemporal resolution. In this review, we highlight the recent progress in the methods for labeling mRNA targets and analyzing the quantitative information from fluorescence images of single mRNA molecules. In particular, the MS2 system and its various applications are the main focus of this article. We also review how recent studies have addressed biological questions related to the significance of mRNA localization in vivo. Efforts to visualize the dynamics of single mRNA molecules in live cells will push forward our knowledge on the nature of heterogeneity in RNA sequence, structure, and distribution as well as their molecular function and coordinated interaction with RNA binding proteins." @default.
- W2896770208 created "2018-10-26" @default.
- W2896770208 creator A5002475551 @default.
- W2896770208 creator A5004487444 @default.
- W2896770208 creator A5012298628 @default.
- W2896770208 creator A5021135697 @default.
- W2896770208 creator A5061942033 @default.
- W2896770208 date "2018-11-14" @default.
- W2896770208 modified "2023-10-14" @default.
- W2896770208 title "Recent progress in single-molecule studies of mRNA localization <i>in vivo</i>" @default.
- W2896770208 cites W1489990234 @default.
- W2896770208 cites W149540474 @default.
- W2896770208 cites W1495424948 @default.
- W2896770208 cites W1529873843 @default.
- W2896770208 cites W1537435459 @default.
- W2896770208 cites W1553227677 @default.
- W2896770208 cites W1899502773 @default.
- W2896770208 cites W1935883651 @default.
- W2896770208 cites W1964259728 @default.
- W2896770208 cites W1964658455 @default.
- W2896770208 cites W1964929903 @default.
- W2896770208 cites W1967510273 @default.
- W2896770208 cites W1968782960 @default.
- W2896770208 cites W1970215478 @default.
- W2896770208 cites W1974078141 @default.
- W2896770208 cites W1975669874 @default.
- W2896770208 cites W1975680667 @default.
- W2896770208 cites W1976135176 @default.
- W2896770208 cites W1976647752 @default.
- W2896770208 cites W1980992607 @default.
- W2896770208 cites W1981765336 @default.
- W2896770208 cites W1983358637 @default.
- W2896770208 cites W1986911150 @default.
- W2896770208 cites W1991615598 @default.
- W2896770208 cites W1993981485 @default.
- W2896770208 cites W1994200894 @default.
- W2896770208 cites W1996655390 @default.
- W2896770208 cites W1998904894 @default.
- W2896770208 cites W2004872614 @default.
- W2896770208 cites W2009743304 @default.
- W2896770208 cites W2012338406 @default.
- W2896770208 cites W2013301809 @default.
- W2896770208 cites W2013990977 @default.
- W2896770208 cites W2014426887 @default.
- W2896770208 cites W2017886758 @default.
- W2896770208 cites W2017934591 @default.
- W2896770208 cites W2018822137 @default.
- W2896770208 cites W2024685809 @default.
- W2896770208 cites W2025914535 @default.
- W2896770208 cites W2026710381 @default.
- W2896770208 cites W2027267723 @default.
- W2896770208 cites W2028317903 @default.
- W2896770208 cites W2030263649 @default.
- W2896770208 cites W2030974598 @default.
- W2896770208 cites W2035239320 @default.
- W2896770208 cites W2036173816 @default.
- W2896770208 cites W2048372307 @default.
- W2896770208 cites W2049222491 @default.
- W2896770208 cites W2050216257 @default.
- W2896770208 cites W2052791231 @default.
- W2896770208 cites W2052936390 @default.
- W2896770208 cites W2058681782 @default.
- W2896770208 cites W2067612240 @default.
- W2896770208 cites W2068427957 @default.
- W2896770208 cites W2073987430 @default.
- W2896770208 cites W2077487258 @default.
- W2896770208 cites W2080562735 @default.
- W2896770208 cites W2081886031 @default.
- W2896770208 cites W2087211196 @default.
- W2896770208 cites W2089833507 @default.
- W2896770208 cites W2092154357 @default.
- W2896770208 cites W2094063999 @default.
- W2896770208 cites W2100794056 @default.
- W2896770208 cites W2101880374 @default.
- W2896770208 cites W2105916176 @default.
- W2896770208 cites W2107777962 @default.
- W2896770208 cites W2108080167 @default.
- W2896770208 cites W2108979661 @default.
- W2896770208 cites W2110943394 @default.
- W2896770208 cites W2111271983 @default.
- W2896770208 cites W2113525941 @default.
- W2896770208 cites W2116780065 @default.
- W2896770208 cites W2117875674 @default.
- W2896770208 cites W2118612419 @default.
- W2896770208 cites W2119191737 @default.
- W2896770208 cites W2126103959 @default.
- W2896770208 cites W2127540003 @default.
- W2896770208 cites W2128942354 @default.
- W2896770208 cites W2131162901 @default.
- W2896770208 cites W2132918077 @default.
- W2896770208 cites W2137232836 @default.
- W2896770208 cites W2146152985 @default.
- W2896770208 cites W2152605992 @default.
- W2896770208 cites W2161628037 @default.
- W2896770208 cites W2163482144 @default.
- W2896770208 cites W2167491742 @default.
- W2896770208 cites W2168136381 @default.
- W2896770208 cites W2169373177 @default.