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- W2896792360 abstract "In this work, superparamagnetic nanohybrid material Fe 3 O 4 /NH 2 ‐Ag is uncovered as an attractive magnetic carrier for the controlled delivery of acyclovir (ACV). This magnetic nanoparticle was synthesized using the hydrothermal method. Then, the surface hydroxyl groups were extended by treating with tetraethyl orthosilicate (TEOS) and (3‐aminopropyl) trimethoxysilane (APTMS). Finally, Ag nanoparticles were created on the surface of Fe 3 O 4 @SiO 2 ‐NH 2 nanospheres via reduction of Ag + ions. Decorated hybrid magnetite nanoparticles were then loaded with ACV as an active antiviral drug model. For this purpose, the amount of loading/release of the drug was investigated at different pH values. Structural characteristics of the functionalized nanomagnetic materials were investigated by Fourier transform‐infrared spectroscopy, transmission electron microscopy, X‐ray diffraction, thermogravimetric analysis and vibrating‐sample magnetometry. The findings indicated that Fe 3 O 4 /NH 2 ‐Ag is highly efficient in loading and release of the selected model drug at pH 7.4." @default.
- W2896792360 created "2018-10-26" @default.
- W2896792360 creator A5001679805 @default.
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- W2896792360 date "2018-10-18" @default.
- W2896792360 modified "2023-10-18" @default.
- W2896792360 title "Synthesis and characterization of superparamagnetic nanohybrid Fe<sub>3</sub> O<sub>4</sub> /NH<sub>2</sub> -Ag as an effective carrier for the delivery of acyclovir" @default.
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- W2896792360 doi "https://doi.org/10.1002/aoc.4565" @default.
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