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- W2896819957 abstract "Multidrug resistance (MDR), defined as the cross-resistance of cancer cells toward a broad range of chemotherapeutic agents, is a universal and intractable problem in chemotherapy. The understanding of MDR mechanisms is essential to discover the potential biomarkers for predicting multidrug resistance and more importantly, tackling and preventing multidrug resistance. Multiple technologies have been used to study MDR mechanisms including comparative genomic hybridization, DNA array, differential display RT-PCR and various immunoassays. Compared with these approaches, proteomic technologies allow a high through-put analysis of protein detection, protein quantification and protein interaction with high accuracy. With the rapid development of proteomic studies in recent years, proteomic technologies have made substantial contributions to the characterization of MDR mechanisms including MDR-related protein detection and quantification, as well as the characterization of drug-transporter binding sites. This review offers a comprehensive illustration of MDR, proteomic technologies and the discoveries made in understanding MDR mechanisms using proteomic approaches." @default.
- W2896819957 created "2018-10-26" @default.
- W2896819957 creator A5003355586 @default.
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- W2896819957 creator A5044904210 @default.
- W2896819957 creator A5056228195 @default.
- W2896819957 creator A5079983839 @default.
- W2896819957 date "2019-01-01" @default.
- W2896819957 modified "2023-09-24" @default.
- W2896819957 title "The use of proteomic technologies to study molecular mechanisms of multidrug resistance in cancer" @default.
- W2896819957 cites W147439079 @default.
- W2896819957 cites W1541083168 @default.
- W2896819957 cites W1577206371 @default.
- W2896819957 cites W1578072993 @default.
- W2896819957 cites W1589402586 @default.
- W2896819957 cites W1606423922 @default.
- W2896819957 cites W1607134312 @default.
- W2896819957 cites W1956702905 @default.
- W2896819957 cites W1965942536 @default.
- W2896819957 cites W1966597938 @default.
- W2896819957 cites W1968046362 @default.
- W2896819957 cites W1968559986 @default.
- W2896819957 cites W1974992308 @default.
- W2896819957 cites W1975558168 @default.
- W2896819957 cites W1977403160 @default.
- W2896819957 cites W1978872452 @default.
- W2896819957 cites W1982201527 @default.
- W2896819957 cites W1988556197 @default.
- W2896819957 cites W1988605167 @default.
- W2896819957 cites W1992271736 @default.
- W2896819957 cites W1992401642 @default.
- W2896819957 cites W1994318934 @default.
- W2896819957 cites W1994363041 @default.
- W2896819957 cites W1998595310 @default.
- W2896819957 cites W1999163695 @default.
- W2896819957 cites W2001376439 @default.
- W2896819957 cites W2003261719 @default.
- W2896819957 cites W2006434892 @default.
- W2896819957 cites W2007649418 @default.
- W2896819957 cites W2007796044 @default.
- W2896819957 cites W2009876678 @default.
- W2896819957 cites W2011105822 @default.
- W2896819957 cites W2014816816 @default.
- W2896819957 cites W2018628280 @default.
- W2896819957 cites W2019021865 @default.
- W2896819957 cites W2023096047 @default.
- W2896819957 cites W2023570843 @default.
- W2896819957 cites W2024532487 @default.
- W2896819957 cites W2024707673 @default.
- W2896819957 cites W2025058643 @default.
- W2896819957 cites W2026566313 @default.
- W2896819957 cites W2028931227 @default.
- W2896819957 cites W2029910949 @default.
- W2896819957 cites W2030462329 @default.
- W2896819957 cites W2031315018 @default.
- W2896819957 cites W2036459315 @default.
- W2896819957 cites W2036926586 @default.
- W2896819957 cites W2037837681 @default.
- W2896819957 cites W2038392824 @default.
- W2896819957 cites W2042496715 @default.
- W2896819957 cites W2044532561 @default.
- W2896819957 cites W2044583833 @default.
- W2896819957 cites W2044911368 @default.
- W2896819957 cites W2044914821 @default.
- W2896819957 cites W2046451859 @default.
- W2896819957 cites W2047275456 @default.
- W2896819957 cites W2048217586 @default.
- W2896819957 cites W2049110191 @default.
- W2896819957 cites W2050412349 @default.
- W2896819957 cites W2052366563 @default.
- W2896819957 cites W2052866415 @default.
- W2896819957 cites W2055904567 @default.
- W2896819957 cites W2065992894 @default.
- W2896819957 cites W2069617042 @default.
- W2896819957 cites W2070330415 @default.
- W2896819957 cites W2075038502 @default.
- W2896819957 cites W2077890471 @default.
- W2896819957 cites W2079176745 @default.
- W2896819957 cites W2080019806 @default.
- W2896819957 cites W2081723349 @default.
- W2896819957 cites W2084371790 @default.
- W2896819957 cites W2087905278 @default.
- W2896819957 cites W2088227103 @default.
- W2896819957 cites W2088817932 @default.
- W2896819957 cites W2089798261 @default.
- W2896819957 cites W2094303590 @default.
- W2896819957 cites W2097532953 @default.
- W2896819957 cites W2101382252 @default.
- W2896819957 cites W2103174300 @default.
- W2896819957 cites W2114557817 @default.
- W2896819957 cites W2115212992 @default.
- W2896819957 cites W2115250484 @default.
- W2896819957 cites W2115397673 @default.
- W2896819957 cites W2118577784 @default.
- W2896819957 cites W2120624849 @default.