Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896825764> ?p ?o ?g. }
- W2896825764 endingPage "49" @default.
- W2896825764 startingPage "42" @default.
- W2896825764 abstract "Macrophages are phagocytic immune cells resident in every tissue that are not only important for host defence, but are also involved in tissue homeostasis, injury, and disease. Despite increasingly sophisticated methods for in vitro macrophage isolation, expansion and activation over the past three decades, these have largely been restricted to modelling bone-marrow or blood-derived cells. The in vitro derivation of macrophages from human pluripotent stem cells provides new opportunities to study macrophage biology, including the factors that impact human myeloid development and those that induce macrophage activation. While sharing many of the functional characteristics of monocyte-derived macrophages, stem cell-derived macrophages may offer new opportunities to understand the role of development or tissue context in innate immune cell function. Immune responsiveness to pathogenic challenge is known to be impacted by a macrophage's history of prior exposure, as well as ontogeny and tissue context. Therefore, we explore the factors of in vitro derivation likely to influence macrophage phenotype and function." @default.
- W2896825764 created "2018-10-26" @default.
- W2896825764 creator A5013036495 @default.
- W2896825764 creator A5051164414 @default.
- W2896825764 creator A5060059951 @default.
- W2896825764 creator A5072188738 @default.
- W2896825764 date "2018-11-01" @default.
- W2896825764 modified "2023-09-25" @default.
- W2896825764 title "Designer macrophages: Pitfalls and opportunities for modelling macrophage phenotypes from pluripotent stem cells" @default.
- W2896825764 cites W1482326448 @default.
- W2896825764 cites W1507275598 @default.
- W2896825764 cites W1515725948 @default.
- W2896825764 cites W1555808520 @default.
- W2896825764 cites W1925667723 @default.
- W2896825764 cites W1942388905 @default.
- W2896825764 cites W1964818843 @default.
- W2896825764 cites W1973433801 @default.
- W2896825764 cites W1978961715 @default.
- W2896825764 cites W1980789245 @default.
- W2896825764 cites W1986852869 @default.
- W2896825764 cites W1995554298 @default.
- W2896825764 cites W2005391565 @default.
- W2896825764 cites W2010353459 @default.
- W2896825764 cites W2011687861 @default.
- W2896825764 cites W2011856955 @default.
- W2896825764 cites W2023293636 @default.
- W2896825764 cites W2023666964 @default.
- W2896825764 cites W2039730578 @default.
- W2896825764 cites W2041308303 @default.
- W2896825764 cites W2049737261 @default.
- W2896825764 cites W2052757433 @default.
- W2896825764 cites W2058815861 @default.
- W2896825764 cites W2059613235 @default.
- W2896825764 cites W2060813891 @default.
- W2896825764 cites W2065328410 @default.
- W2896825764 cites W2065561900 @default.
- W2896825764 cites W2071172792 @default.
- W2896825764 cites W2077087448 @default.
- W2896825764 cites W2081020145 @default.
- W2896825764 cites W2082363951 @default.
- W2896825764 cites W2088778855 @default.
- W2896825764 cites W2100646399 @default.
- W2896825764 cites W2109570573 @default.
- W2896825764 cites W2121999038 @default.
- W2896825764 cites W2126811287 @default.
- W2896825764 cites W2136188258 @default.
- W2896825764 cites W2140347191 @default.
- W2896825764 cites W2140876277 @default.
- W2896825764 cites W2142492088 @default.
- W2896825764 cites W2146560578 @default.
- W2896825764 cites W2153406260 @default.
- W2896825764 cites W2159560463 @default.
- W2896825764 cites W2162166699 @default.
- W2896825764 cites W2163149880 @default.
- W2896825764 cites W2164470216 @default.
- W2896825764 cites W2226290723 @default.
- W2896825764 cites W2287116530 @default.
- W2896825764 cites W2343063221 @default.
- W2896825764 cites W2464581224 @default.
- W2896825764 cites W2466626717 @default.
- W2896825764 cites W2506892818 @default.
- W2896825764 cites W2525538087 @default.
- W2896825764 cites W2575042032 @default.
- W2896825764 cites W2589917023 @default.
- W2896825764 cites W2593638094 @default.
- W2896825764 cites W2605401453 @default.
- W2896825764 cites W2605696370 @default.
- W2896825764 cites W2610140032 @default.
- W2896825764 cites W2614953780 @default.
- W2896825764 cites W2619332462 @default.
- W2896825764 cites W2620810594 @default.
- W2896825764 cites W2623352127 @default.
- W2896825764 cites W266652616 @default.
- W2896825764 cites W2736895630 @default.
- W2896825764 cites W2752228441 @default.
- W2896825764 cites W2763908993 @default.
- W2896825764 cites W2766952563 @default.
- W2896825764 cites W2773512909 @default.
- W2896825764 cites W2781660900 @default.
- W2896825764 cites W2789309735 @default.
- W2896825764 cites W2801493344 @default.
- W2896825764 cites W2801573336 @default.
- W2896825764 cites W2888803570 @default.
- W2896825764 cites W2952814417 @default.
- W2896825764 cites W4238410058 @default.
- W2896825764 doi "https://doi.org/10.1016/j.diff.2018.10.001" @default.
- W2896825764 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30453197" @default.
- W2896825764 hasPublicationYear "2018" @default.
- W2896825764 type Work @default.
- W2896825764 sameAs 2896825764 @default.
- W2896825764 citedByCount "13" @default.
- W2896825764 countsByYear W28968257642019 @default.
- W2896825764 countsByYear W28968257642020 @default.
- W2896825764 countsByYear W28968257642021 @default.
- W2896825764 countsByYear W28968257642022 @default.
- W2896825764 countsByYear W28968257642023 @default.
- W2896825764 crossrefType "journal-article" @default.
- W2896825764 hasAuthorship W2896825764A5013036495 @default.