FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896857164> ?p ?o ?g. }

• W2896857164 abstract "Metallothioneins (MT) are multi-stress proteins mainly involved in metal detoxification. MT gene expression is normally induced by a broad variety of stimulus and its gene expression regulation mainly occurs at a transcriptional level. Conserved motifs in the T. thermophila MT promoters have been described. These motifs show a consensus sequence very similar to AP-1 sites, and bZIP type transcription factors might participate in the MT gene expression regulation. In this research work, we characterize four AP-1 transcription factors in each of four different analysed Tetrahymena species, detecting a high conservation among them. Each AP-1 molecule has its counterpart in the other three Tetrahymena species. A comparative qRT-PCR analysis of these AP-1 genes have been carried out in different T. thermophila strains (including metal-adapted, knockout and/or knockdown strains among others), and under different metal-stress conditions (1 or 24h Cd2+, Cu2+ or Pb2+ treatments). The possible interaction of these transcription factors with the conserved AP-1 motifs present in MT promoters has been corroborated by protein-DNA interaction experiments. Certain connection between the expression patterns of the bZIP and MT genes seems to exist. For the first time, and based on our findings,a possible gene expression regulation model including both AP-1 transcription factors and MT genes from the ciliate T. thermophila has been elaborated." @default.
• W2896857164 created "2018-10-26" @default.
• W2896857164 creator A5012019388 @default.
• W2896857164 creator A5036910983 @default.
• W2896857164 creator A5040114656 @default.
• W2896857164 creator A5082789309 @default.
• W2896857164 date "2018-10-23" @default.
• W2896857164 modified "2023-10-17" @default.
• W2896857164 title "AP-1 (bZIP) Transcription Factors as Potential Regulators of Metallothionein Gene Expression in Tetrahymena thermophila" @default.
• W2896857164 cites W146440179 @default.
• W2896857164 cites W1506057870 @default.
• W2896857164 cites W1578589309 @default.
• W2896857164 cites W1592870802 @default.
• W2896857164 cites W1754721961 @default.
• W2896857164 cites W1803102843 @default.
• W2896857164 cites W1823814103 @default.
• W2896857164 cites W1972204004 @default.
• W2896857164 cites W1976260744 @default.
• W2896857164 cites W1983357242 @default.
• W2896857164 cites W1990659515 @default.
• W2896857164 cites W1991786835 @default.
• W2896857164 cites W1993457994 @default.
• W2896857164 cites W1994219871 @default.
• W2896857164 cites W1996956941 @default.
• W2896857164 cites W1998130451 @default.
• W2896857164 cites W1998398302 @default.
• W2896857164 cites W1999568705 @default.
• W2896857164 cites W2007506049 @default.
• W2896857164 cites W2017575645 @default.
• W2896857164 cites W2024645073 @default.
• W2896857164 cites W2026949621 @default.
• W2896857164 cites W2036128545 @default.
• W2896857164 cites W2036224418 @default.
• W2896857164 cites W204029877 @default.
• W2896857164 cites W2046281013 @default.
• W2896857164 cites W2048746397 @default.
• W2896857164 cites W2049949159 @default.
• W2896857164 cites W2061154752 @default.
• W2896857164 cites W2064832070 @default.
• W2896857164 cites W2070260068 @default.
• W2896857164 cites W2078076779 @default.
• W2896857164 cites W2084939005 @default.
• W2896857164 cites W2086161594 @default.
• W2896857164 cites W2086390365 @default.
• W2896857164 cites W2092806862 @default.
• W2896857164 cites W2101629470 @default.
• W2896857164 cites W2102165823 @default.
• W2896857164 cites W210358448 @default.
• W2896857164 cites W2103672917 @default.
• W2896857164 cites W2107185020 @default.
• W2896857164 cites W2115632430 @default.
• W2896857164 cites W2128701949 @default.
• W2896857164 cites W2131924932 @default.
• W2896857164 cites W2135619531 @default.
• W2896857164 cites W2140665078 @default.
• W2896857164 cites W2141513355 @default.
• W2896857164 cites W2141642957 @default.
• W2896857164 cites W2142701968 @default.
• W2896857164 cites W2144362290 @default.
• W2896857164 cites W2153187042 @default.
• W2896857164 cites W2196856797 @default.
• W2896857164 cites W2270581102 @default.
• W2896857164 cites W2346270715 @default.
• W2896857164 cites W2605190590 @default.
• W2896857164 cites W2775590454 @default.
• W2896857164 cites W2801361324 @default.
• W2896857164 cites W4205372329 @default.
• W2896857164 cites W4246652680 @default.
• W2896857164 doi "https://doi.org/10.3389/fgene.2018.00459" @default.
• W2896857164 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6205968" @default.
• W2896857164 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30405686" @default.
• W2896857164 hasPublicationYear "2018" @default.
• W2896857164 type Work @default.
• W2896857164 sameAs 2896857164 @default.
• W2896857164 citedByCount "1" @default.
• W2896857164 countsByYear W28968571642020 @default.
• W2896857164 crossrefType "journal-article" @default.
• W2896857164 hasAuthorship W2896857164A5012019388 @default.
• W2896857164 hasAuthorship W2896857164A5036910983 @default.
• W2896857164 hasAuthorship W2896857164A5040114656 @default.
• W2896857164 hasAuthorship W2896857164A5082789309 @default.
• W2896857164 hasBestOaLocation W28968571641 @default.
• W2896857164 hasConcept C101762097 @default.
• W2896857164 hasConcept C104317684 @default.
• W2896857164 hasConcept C138885662 @default.
• W2896857164 hasConcept C150194340 @default.
• W2896857164 hasConcept C165864922 @default.
• W2896857164 hasConcept C167625842 @default.
• W2896857164 hasConcept C173396325 @default.
• W2896857164 hasConcept C179926584 @default.
• W2896857164 hasConcept C199216141 @default.
• W2896857164 hasConcept C27153228 @default.
• W2896857164 hasConcept C2777166614 @default.
• W2896857164 hasConcept C41895202 @default.
• W2896857164 hasConcept C54355233 @default.
• W2896857164 hasConcept C86339819 @default.
• W2896857164 hasConcept C86803240 @default.
• W2896857164 hasConcept C95444343 @default.
• W2896857164 hasConceptScore W2896857164C101762097 @default.
• W2896857164 hasConceptScore W2896857164C104317684 @default.

• next