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• W2896857473 abstract "High-risk human papillomavirus (hrHPV) causes cervical cancer. In the United States, approximately 40% of women aged 14–59 years from all racial and ethnic groups are infected with HPV, and prevalence typically declines with age. However, American Indian (AI) women are insufficiently sampled to permit a population-specific estimate of hrHPV prevalence. Vaginal swabs were self-collected by 698 AI women aged 21–65 years from a tribal community in the Great Plains. We estimated the population prevalence of hrHPV and identified predominant genotypes. The combined prevalence of hrHPV genotypes 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68 was 34.8%. HPV-51 (7.6%), HPV-58 (5.3%), HPV-52 (4.3%), HPV-18 (4.3%), and HPV-16 (3.9%) were most prevalent. hrHPV prevalence declined with age, from 42.2% in women aged 21–24 years to 27.9% in women aged 50–65 years. HPV-51 was the single most prevalent oncogenic genotype. The combined prevalence of hrHPV among AI women in our sample was high, particularly among women aged 50–65 years, for whom hrHPV prevalence was approximately triple that of other races. Cervical cancer screening efforts should be increased, particularly among women from the community aged 30 years and older." @default.
• W2896857473 created "2018-10-26" @default.
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• W2896857473 date "2018-10-15" @default.
• W2896857473 modified "2023-10-16" @default.
• W2896857473 title "Human Papillomavirus Prevalence Among American Indian Women of the Great Plains" @default.
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• W2896857473 doi "https://doi.org/10.1093/infdis/jiy600" @default.
• W2896857473 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6386810" @default.
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