Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896860301> ?p ?o ?g. }
- W2896860301 endingPage "3926" @default.
- W2896860301 startingPage "3918" @default.
- W2896860301 abstract "Many bacterial pathogens rely on quorum sensing to control virulence gene expression. Based on numerous experiments conducted under well-defined conditions, quorum sensing interference is considered as a promising strategy to tackle infections and thus might have the potential to (partially) replace antibiotics. Despite the promising results in well-defined (artificial) laboratory experiments, there still is a lack of knowledge with respect to the impact of quorum sensing interference on the fitness of pathogens in more realistic scenarios, including interactions with a host, the external environment and complex microbial communities. In this article, we critically evaluate the current knowledge with respect to these three facets of the real world that can affect the fitness of quorum sensing bacterial pathogens. We argue that further research is needed in order to determine how these factors interplay with quorum sensing and to what extent they can influence the selective pressure that might be exerted by quorum sensing interference (and thus determine the risk of resistance development against quorum sensing interference). This kind of information is indispensable in order to optimize quorum sensing interference-based therapeutic strategies." @default.
- W2896860301 created "2018-10-26" @default.
- W2896860301 creator A5007670808 @default.
- W2896860301 creator A5061586713 @default.
- W2896860301 creator A5068500219 @default.
- W2896860301 date "2018-10-30" @default.
- W2896860301 modified "2023-09-26" @default.
- W2896860301 title "Does quorum sensing interference affect the fitness of bacterial pathogens in the real world?" @default.
- W2896860301 cites W1489973623 @default.
- W2896860301 cites W1497150576 @default.
- W2896860301 cites W1498791242 @default.
- W2896860301 cites W1544313894 @default.
- W2896860301 cites W1894075467 @default.
- W2896860301 cites W1935018540 @default.
- W2896860301 cites W1956528654 @default.
- W2896860301 cites W1973843350 @default.
- W2896860301 cites W1976555793 @default.
- W2896860301 cites W1977809773 @default.
- W2896860301 cites W1979152503 @default.
- W2896860301 cites W1979211796 @default.
- W2896860301 cites W1979888857 @default.
- W2896860301 cites W1983455597 @default.
- W2896860301 cites W1987348183 @default.
- W2896860301 cites W1999926887 @default.
- W2896860301 cites W2007002493 @default.
- W2896860301 cites W2018917527 @default.
- W2896860301 cites W2036148129 @default.
- W2896860301 cites W2039556608 @default.
- W2896860301 cites W2040605556 @default.
- W2896860301 cites W2041715796 @default.
- W2896860301 cites W2046340722 @default.
- W2896860301 cites W2049174722 @default.
- W2896860301 cites W2058571049 @default.
- W2896860301 cites W2061156492 @default.
- W2896860301 cites W2066846401 @default.
- W2896860301 cites W2069503235 @default.
- W2896860301 cites W2076026970 @default.
- W2896860301 cites W2081274087 @default.
- W2896860301 cites W2101773986 @default.
- W2896860301 cites W2103466597 @default.
- W2896860301 cites W2105591146 @default.
- W2896860301 cites W2108808146 @default.
- W2896860301 cites W2111499050 @default.
- W2896860301 cites W2116429397 @default.
- W2896860301 cites W2117160134 @default.
- W2896860301 cites W2117875102 @default.
- W2896860301 cites W2118521369 @default.
- W2896860301 cites W2122814663 @default.
- W2896860301 cites W2129623714 @default.
- W2896860301 cites W2131749746 @default.
- W2896860301 cites W2131869707 @default.
- W2896860301 cites W2133900508 @default.
- W2896860301 cites W2136731386 @default.
- W2896860301 cites W2138350975 @default.
- W2896860301 cites W2140195816 @default.
- W2896860301 cites W2146292204 @default.
- W2896860301 cites W2149213807 @default.
- W2896860301 cites W2150691479 @default.
- W2896860301 cites W2154043802 @default.
- W2896860301 cites W2165838283 @default.
- W2896860301 cites W2222642144 @default.
- W2896860301 cites W2268587872 @default.
- W2896860301 cites W2406413290 @default.
- W2896860301 cites W2471638024 @default.
- W2896860301 cites W2510668779 @default.
- W2896860301 cites W2511722628 @default.
- W2896860301 cites W2527269210 @default.
- W2896860301 cites W2529210292 @default.
- W2896860301 cites W2552957870 @default.
- W2896860301 cites W2555970702 @default.
- W2896860301 cites W2558989591 @default.
- W2896860301 cites W2591284522 @default.
- W2896860301 cites W2598898392 @default.
- W2896860301 cites W2609591691 @default.
- W2896860301 cites W2747825583 @default.
- W2896860301 cites W2766873890 @default.
- W2896860301 cites W2767921398 @default.
- W2896860301 cites W2768039920 @default.
- W2896860301 cites W2770252239 @default.
- W2896860301 cites W2779670201 @default.
- W2896860301 cites W2781512529 @default.
- W2896860301 cites W2783984468 @default.
- W2896860301 cites W2785639135 @default.
- W2896860301 cites W2791768957 @default.
- W2896860301 cites W2804076141 @default.
- W2896860301 cites W2804778852 @default.
- W2896860301 cites W2811451255 @default.
- W2896860301 doi "https://doi.org/10.1111/1462-2920.14446" @default.
- W2896860301 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30318710" @default.
- W2896860301 hasPublicationYear "2018" @default.
- W2896860301 type Work @default.
- W2896860301 sameAs 2896860301 @default.
- W2896860301 citedByCount "12" @default.
- W2896860301 countsByYear W28968603012019 @default.
- W2896860301 countsByYear W28968603012020 @default.
- W2896860301 countsByYear W28968603012021 @default.
- W2896860301 countsByYear W28968603012022 @default.
- W2896860301 countsByYear W28968603012023 @default.