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- W2896886822 abstract "To determine the accuracy of Fungitell, a β-d-glucan (BDG) test, for the diagnosis of invasive fungal infection (IFI) among cancer patients.For this meta-analysis, MEDLINE and EMBASE were searched for references related to BDG testing. Study quality was evaluated using QUADAS-2. Statistical analysis was performed using Stata 14.We screened 12,426 references and identified 189 studies for full-text review. Nineteen studies were included in the final meta-analysis. There was moderate heterogeneity between studies. Nine studies had a high risk of bias, which significantly elevated the overall specificity estimate. Restricting to only low-bias studies, the sensitivity and specificity were 80% and 63%, respectively.The overall sensitivity and specificity of Fungitell as a diagnostic test for IFI is moderate, and there is substantial heterogeneity between studies. Limiting studies to only low-bias risk reduced heterogeneity but also lowered the overall specificity estimate." @default.
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- W2896886822 date "2018-10-10" @default.
- W2896886822 modified "2023-09-30" @default.
- W2896886822 title "Diagnostic Accuracy of β-<scp>d</scp>-Glucan (Fungitell) Testing Among Patients With Hematologic Malignancies or Solid Organ Tumors" @default.
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- W2896886822 doi "https://doi.org/10.1093/ajcp/aqy135" @default.
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