FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896897306> ?p ?o ?g. }

• W2896897306 startingPage "210294" @default.
• W2896897306 abstract "Variation in gut microbiome is associated with wellness and disease in humans, yet the molecular mechanisms by which this variation affects the host are not well understood. A likely mechanism is through changing gene regulation in interfacing host epithelial cells. Here, we treated colonic epithelial cells with live microbiota from five healthy individuals and quantified transcriptional response in host cells. We identified over 5,000 host genes that change expression, including 588 distinct associations between specific taxa and host genes. The taxa with the strongest influence on gene expression, alter the response of genes associated with complex traits. We then created a manipulated microbial community with titrated doses of Collinsella, demonstrating that both natural and controlled microbiome composition leads to distinct, and predictable, gene expression profiles in the host. This ability to fine tune the expression of host genes by manipulating the microbiome suggests future therapeutic routes for human wellness." @default.
• W2896897306 created "2018-10-26" @default.
• W2896897306 creator A5000151794 @default.
• W2896897306 creator A5006339007 @default.
• W2896897306 creator A5012596437 @default.
• W2896897306 creator A5029704166 @default.
• W2896897306 creator A5030188525 @default.
• W2896897306 creator A5034094002 @default.
• W2896897306 creator A5035820223 @default.
• W2896897306 creator A5045777431 @default.
• W2896897306 creator A5084295153 @default.
• W2896897306 date "2017-10-27" @default.
• W2896897306 modified "2023-09-23" @default.
• W2896897306 title "Variation in gut microbiota composition impacts host gene expression" @default.
• W2896897306 cites W1607743621 @default.
• W2896897306 cites W1862711637 @default.
• W2896897306 cites W1948774627 @default.
• W2896897306 cites W1980914602 @default.
• W2896897306 cites W2005258869 @default.
• W2896897306 cites W2024601462 @default.
• W2896897306 cites W2038217946 @default.
• W2896897306 cites W2043442946 @default.
• W2896897306 cites W2057632593 @default.
• W2896897306 cites W2063856799 @default.
• W2896897306 cites W2082578477 @default.
• W2896897306 cites W2087996699 @default.
• W2896897306 cites W2097319008 @default.
• W2896897306 cites W2097875133 @default.
• W2896897306 cites W2100096695 @default.
• W2896897306 cites W2105190780 @default.
• W2896897306 cites W2116846792 @default.
• W2896897306 cites W2116868464 @default.
• W2896897306 cites W2121187468 @default.
• W2896897306 cites W2125784987 @default.
• W2896897306 cites W2125826054 @default.
• W2896897306 cites W2128769815 @default.
• W2896897306 cites W2131415145 @default.
• W2896897306 cites W2135787796 @default.
• W2896897306 cites W2135989088 @default.
• W2896897306 cites W2136500114 @default.
• W2896897306 cites W2136552678 @default.
• W2896897306 cites W2149573313 @default.
• W2896897306 cites W2158341557 @default.
• W2896897306 cites W2162088497 @default.
• W2896897306 cites W2165462132 @default.
• W2896897306 cites W2170245265 @default.
• W2896897306 cites W2171723226 @default.
• W2896897306 cites W2310707027 @default.
• W2896897306 cites W2345810007 @default.
• W2896897306 cites W2521042841 @default.
• W2896897306 cites W2604323123 @default.
• W2896897306 cites W2604594755 @default.
• W2896897306 cites W2729701074 @default.
• W2896897306 cites W2952760726 @default.
• W2896897306 hasPublicationYear "2017" @default.
• W2896897306 type Work @default.
• W2896897306 sameAs 2896897306 @default.
• W2896897306 citedByCount "0" @default.
• W2896897306 crossrefType "posted-content" @default.
• W2896897306 hasAuthorship W2896897306A5000151794 @default.
• W2896897306 hasAuthorship W2896897306A5006339007 @default.
• W2896897306 hasAuthorship W2896897306A5012596437 @default.
• W2896897306 hasAuthorship W2896897306A5029704166 @default.
• W2896897306 hasAuthorship W2896897306A5030188525 @default.
• W2896897306 hasAuthorship W2896897306A5034094002 @default.
• W2896897306 hasAuthorship W2896897306A5035820223 @default.
• W2896897306 hasAuthorship W2896897306A5045777431 @default.
• W2896897306 hasAuthorship W2896897306A5084295153 @default.
• W2896897306 hasBestOaLocation W28968973061 @default.
• W2896897306 hasConcept C104317684 @default.
• W2896897306 hasConcept C126831891 @default.
• W2896897306 hasConcept C143121216 @default.
• W2896897306 hasConcept C150194340 @default.
• W2896897306 hasConcept C165864922 @default.
• W2896897306 hasConcept C18431079 @default.
• W2896897306 hasConcept C54355233 @default.
• W2896897306 hasConcept C86803240 @default.
• W2896897306 hasConceptScore W2896897306C104317684 @default.
• W2896897306 hasConceptScore W2896897306C126831891 @default.
• W2896897306 hasConceptScore W2896897306C143121216 @default.
• W2896897306 hasConceptScore W2896897306C150194340 @default.
• W2896897306 hasConceptScore W2896897306C165864922 @default.
• W2896897306 hasConceptScore W2896897306C18431079 @default.
• W2896897306 hasConceptScore W2896897306C54355233 @default.
• W2896897306 hasConceptScore W2896897306C86803240 @default.
• W2896897306 hasLocation W28968973061 @default.
• W2896897306 hasLocation W28968973062 @default.
• W2896897306 hasOpenAccess W2896897306 @default.
• W2896897306 hasPrimaryLocation W28968973061 @default.
• W2896897306 hasRelatedWork W2033591591 @default.
• W2896897306 hasRelatedWork W2112577424 @default.
• W2896897306 hasRelatedWork W2149934132 @default.
• W2896897306 hasRelatedWork W2162612026 @default.
• W2896897306 hasRelatedWork W2224802932 @default.
• W2896897306 hasRelatedWork W2603633623 @default.
• W2896897306 hasRelatedWork W2610713765 @default.
• W2896897306 hasRelatedWork W2767365552 @default.
• W2896897306 hasRelatedWork W2897444682 @default.
• W2896897306 hasRelatedWork W2914145609 @default.

• next