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• W2896899595 abstract "Lysine acetylation is one of the most important types of protein post-translational modifications (PTM) that are widely involved in cellular regulatory processes. To fully understand the regulatory mechanism of acetylation, identification of acetylation sites is first and most important. However, experimental identification of protein acetylation sites is often time consuming and expensive. Thus, it is popular that predicts PTM sites by computational methods in recent years. Here, we developed a novel method, ProAcePred 2.0, to predict species-specific prokaryote lysine acetylation sites. In this study, we employed an efficient position-specific analysis strategy information gain method to constitute position-specific window of acetylation peptide, and then incorporated different types of features and adopted elastic net algorithm to optimize feature vectors for model learning. The prediction model achieved area under the receiver operating characteristic curve value of six species in training datasets, which are 0.78, 0.752, 0.783, 0.718, 0.839 and 0.826, of Escherichia coli, Corynebacterium glutamicum, Mycobacterium tuberculosis, Bacillus subtilis, S. typhimurium and Geobacillus kaustophilus, respectively. And our method was highly competitive for the majority of species when compared with other methods by using independent test datasets. In addition, function analyses demonstrated that different organisms were preferentially involved in different biological processes and pathways. The detailed analyses in this paper could help us to understand more of the acetylation mechanism and provide guidance for the related experimental validation. A user-friendly online web service of ProAcePred 2.0 can be freely available at http://computbiol.ncu.edu.cn/PAPred." @default.
• W2896899595 created "2018-10-26" @default.
• W2896899595 creator A5005611002 @default.
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• W2896899595 creator A5010423615 @default.
• W2896899595 creator A5021992806 @default.
• W2896899595 creator A5089248160 @default.
• W2896899595 date "2019-01-01" @default.
• W2896899595 modified "2023-10-09" @default.
• W2896899595 title "Prediction and functional analysis of prokaryote lysine acetylation site by incorporating six types of features into Chou's general PseAAC" @default.
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• W2896899595 cites W1984148780 @default.
• W2896899595 cites W1984481954 @default.
• W2896899595 cites W1987805766 @default.
• W2896899595 cites W1991199546 @default.
• W2896899595 cites W1995173448 @default.
• W2896899595 cites W1999118478 @default.
• W2896899595 cites W2009540433 @default.
• W2896899595 cites W2017324120 @default.
• W2896899595 cites W2017702083 @default.
• W2896899595 cites W2022965734 @default.
• W2896899595 cites W2034070267 @default.
• W2896899595 cites W2035911064 @default.
• W2896899595 cites W2038873127 @default.
• W2896899595 cites W2040631816 @default.
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• W2896899595 doi "https://doi.org/10.1016/j.jtbi.2018.10.047" @default.
• W2896899595 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30365945" @default.
• W2896899595 hasPublicationYear "2019" @default.
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