Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896908608> ?p ?o ?g. }
- W2896908608 endingPage "838" @default.
- W2896908608 startingPage "833" @default.
- W2896908608 abstract "Direct acting antivirals have completely changed the landscape of the treatment of chronic hepatitis C. The management of the few patients who relapse to direct acting antivirals requires a careful analysis of the chances to achieve therapeutic success with a second antiviral course. In this context, the usefulness of viral resistances testing, able to detect resistance-associated substitutions in the viral sequence, is at present a matter of debate. Areas covered: The role of resistance associated substitutions is examined through the evaluation of the data from clinical trials that have assessed the impact of viral resistances on the treatment outcome. Special attention has been paid on the data from re-treatment studies. Expert commentary: The treatment failure in chronic hepatitis C is still a possible event. Therefore, additional real-world clinical data on relapse rates and on the relapse management are welcome to definitely address the clinical guidelines. At present, the testing of viral resistances is an exquisite tool for the choice of the re-treatment schedule. In the near future, widespread use of the most recently registered direct acting antivirals with high barrier to resistance will probably weaken the need of resistance testing as a support in clinical decisions." @default.
- W2896908608 created "2018-10-26" @default.
- W2896908608 creator A5062155863 @default.
- W2896908608 creator A5070138170 @default.
- W2896908608 creator A5087296098 @default.
- W2896908608 date "2018-10-29" @default.
- W2896908608 modified "2023-09-25" @default.
- W2896908608 title "Managing HCV treatment failure and the potential of resistance testing in informing second-line therapy options" @default.
- W2896908608 cites W1807436464 @default.
- W2896908608 cites W2026696289 @default.
- W2896908608 cites W2075335279 @default.
- W2896908608 cites W2085226103 @default.
- W2896908608 cites W2112024536 @default.
- W2896908608 cites W2118526609 @default.
- W2896908608 cites W2118684050 @default.
- W2896908608 cites W2141839071 @default.
- W2896908608 cites W2161578383 @default.
- W2896908608 cites W2163856289 @default.
- W2896908608 cites W2178955735 @default.
- W2896908608 cites W2191957520 @default.
- W2896908608 cites W2269147000 @default.
- W2896908608 cites W2313732802 @default.
- W2896908608 cites W2318156787 @default.
- W2896908608 cites W2345024104 @default.
- W2896908608 cites W2395304453 @default.
- W2896908608 cites W2413213127 @default.
- W2896908608 cites W2436449240 @default.
- W2896908608 cites W2461004176 @default.
- W2896908608 cites W2560002598 @default.
- W2896908608 cites W2575794989 @default.
- W2896908608 cites W2575880746 @default.
- W2896908608 cites W2578013986 @default.
- W2896908608 cites W2588942442 @default.
- W2896908608 cites W2606367578 @default.
- W2896908608 cites W2617500612 @default.
- W2896908608 cites W2624552959 @default.
- W2896908608 cites W2667085915 @default.
- W2896908608 cites W2673162703 @default.
- W2896908608 cites W2687319114 @default.
- W2896908608 cites W2767357661 @default.
- W2896908608 cites W2767749078 @default.
- W2896908608 cites W2789372318 @default.
- W2896908608 cites W2794341756 @default.
- W2896908608 cites W2797607304 @default.
- W2896908608 cites W2806884218 @default.
- W2896908608 cites W4254843569 @default.
- W2896908608 cites W971519378 @default.
- W2896908608 doi "https://doi.org/10.1080/14787210.2018.1538783" @default.
- W2896908608 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30336699" @default.
- W2896908608 hasPublicationYear "2018" @default.
- W2896908608 type Work @default.
- W2896908608 sameAs 2896908608 @default.
- W2896908608 citedByCount "2" @default.
- W2896908608 countsByYear W28969086082023 @default.
- W2896908608 crossrefType "journal-article" @default.
- W2896908608 hasAuthorship W2896908608A5062155863 @default.
- W2896908608 hasAuthorship W2896908608A5070138170 @default.
- W2896908608 hasAuthorship W2896908608A5087296098 @default.
- W2896908608 hasConcept C126322002 @default.
- W2896908608 hasConcept C151730666 @default.
- W2896908608 hasConcept C177713679 @default.
- W2896908608 hasConcept C18903297 @default.
- W2896908608 hasConcept C203014093 @default.
- W2896908608 hasConcept C2522874641 @default.
- W2896908608 hasConcept C2777072776 @default.
- W2896908608 hasConcept C2779343474 @default.
- W2896908608 hasConcept C3020491458 @default.
- W2896908608 hasConcept C535046627 @default.
- W2896908608 hasConcept C57473165 @default.
- W2896908608 hasConcept C71924100 @default.
- W2896908608 hasConcept C86803240 @default.
- W2896908608 hasConceptScore W2896908608C126322002 @default.
- W2896908608 hasConceptScore W2896908608C151730666 @default.
- W2896908608 hasConceptScore W2896908608C177713679 @default.
- W2896908608 hasConceptScore W2896908608C18903297 @default.
- W2896908608 hasConceptScore W2896908608C203014093 @default.
- W2896908608 hasConceptScore W2896908608C2522874641 @default.
- W2896908608 hasConceptScore W2896908608C2777072776 @default.
- W2896908608 hasConceptScore W2896908608C2779343474 @default.
- W2896908608 hasConceptScore W2896908608C3020491458 @default.
- W2896908608 hasConceptScore W2896908608C535046627 @default.
- W2896908608 hasConceptScore W2896908608C57473165 @default.
- W2896908608 hasConceptScore W2896908608C71924100 @default.
- W2896908608 hasConceptScore W2896908608C86803240 @default.
- W2896908608 hasIssue "11" @default.
- W2896908608 hasLocation W28969086081 @default.
- W2896908608 hasLocation W28969086082 @default.
- W2896908608 hasOpenAccess W2896908608 @default.
- W2896908608 hasPrimaryLocation W28969086081 @default.
- W2896908608 hasRelatedWork W1572298971 @default.
- W2896908608 hasRelatedWork W2359884894 @default.
- W2896908608 hasRelatedWork W2366237216 @default.
- W2896908608 hasRelatedWork W2415669925 @default.
- W2896908608 hasRelatedWork W2418867336 @default.
- W2896908608 hasRelatedWork W2622038044 @default.
- W2896908608 hasRelatedWork W4238335663 @default.
- W2896908608 hasRelatedWork W4252371801 @default.
- W2896908608 hasRelatedWork W4281762544 @default.