Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896917448> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2896917448 abstract "To evaluate the clinical efficacy of traditional Chinese medicine (TCM) supplementing Qi and hemostasis formula on gastrointestinal (GI) bleeding after percutaneous coronary intervention (PCI) and thus find out the optimal therapeutic regimen to reduce incidence of GI bleeding without increase of major adverse cardiovascular events (MACEs).In the randomized, double-blinded, controlled trial, 117 participants who underwent PCI were enrolled and evenly distributed into treatment arm (59) and control arm (58). Numerous end points were assessed including the primary endpoint of GI bleeding and MACEs and secondary endpoint of thromboelastogram (TEG) (mainly MAadp, inhibition of ADP, and inhibition of AA) and TCM syndrome score during the follow-up phase of 90 days.Incidence of bleeding including GI bleeding and MACE did not differ significantly between two arms (28.82% in treatment arm versus 24.44% in control). However, on both days 30 and 90, TCM treatment remarkably reduced the TCM syndrome total score with notable alteration (P<0.05) except for some parameters such as pulse manifestation. When it came to TEG, however, MAADP increased significantly on day 30 in control arm, accompanied by a notable descending in inhibition rate of ADP pathway (both P<0.01).(1) Supplementing Qi and hemostasis formula is equal to Pantoprazole Sodium Enteric-Coated Capsule in hemostasis and gastric mucosal protection; (2) supplementing Qi and hemostasis formula is superior to Pantoprazole Sodium Enteric-Coated Capsule in improving TCM syndrome manifestation possibly through the multitarget mechanism; (3) interference on clopidogrel of supplementing Qi and hemostasis formula might be much less than Pantoprazole Sodium Enteric-Coated Capsule due to the potential CYP450-independent mechanism. This trial is registered with ChiCTR1800014485." @default.
- W2896917448 created "2018-10-26" @default.
- W2896917448 creator A5003956280 @default.
- W2896917448 creator A5003979211 @default.
- W2896917448 creator A5019118491 @default.
- W2896917448 creator A5019786283 @default.
- W2896917448 creator A5020130430 @default.
- W2896917448 creator A5031810848 @default.
- W2896917448 creator A5050938339 @default.
- W2896917448 creator A5063600969 @default.
- W2896917448 creator A5075877965 @default.
- W2896917448 creator A5085352453 @default.
- W2896917448 date "2018-10-21" @default.
- W2896917448 modified "2023-10-15" @default.
- W2896917448 title "A Randomized Double-Blind Placebo-Controlled Trial to Evaluate Prophylactic Effect of Traditional Chinese Medicine Supplementing Qi and Hemostasis Formula on Gastrointestinal Bleeding after Percutaneous Coronary Intervention in Patients at High Risks" @default.
- W2896917448 cites W1895918224 @default.
- W2896917448 cites W1991027003 @default.
- W2896917448 cites W2076472818 @default.
- W2896917448 cites W2105489963 @default.
- W2896917448 cites W2106043674 @default.
- W2896917448 cites W2115542336 @default.
- W2896917448 cites W2119186881 @default.
- W2896917448 cites W2395993059 @default.
- W2896917448 cites W2410339670 @default.
- W2896917448 cites W2576906511 @default.
- W2896917448 cites W2750119242 @default.
- W2896917448 cites W4298276187 @default.
- W2896917448 cites W72869980 @default.
- W2896917448 doi "https://doi.org/10.1155/2018/3852196" @default.
- W2896917448 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6215574" @default.
- W2896917448 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30420892" @default.
- W2896917448 hasPublicationYear "2018" @default.
- W2896917448 type Work @default.
- W2896917448 sameAs 2896917448 @default.
- W2896917448 citedByCount "4" @default.
- W2896917448 countsByYear W28969174482019 @default.
- W2896917448 countsByYear W28969174482020 @default.
- W2896917448 countsByYear W28969174482021 @default.
- W2896917448 crossrefType "journal-article" @default.
- W2896917448 hasAuthorship W2896917448A5003956280 @default.
- W2896917448 hasAuthorship W2896917448A5003979211 @default.
- W2896917448 hasAuthorship W2896917448A5019118491 @default.
- W2896917448 hasAuthorship W2896917448A5019786283 @default.
- W2896917448 hasAuthorship W2896917448A5020130430 @default.
- W2896917448 hasAuthorship W2896917448A5031810848 @default.
- W2896917448 hasAuthorship W2896917448A5050938339 @default.
- W2896917448 hasAuthorship W2896917448A5063600969 @default.
- W2896917448 hasAuthorship W2896917448A5075877965 @default.
- W2896917448 hasAuthorship W2896917448A5085352453 @default.
- W2896917448 hasBestOaLocation W28969174481 @default.
- W2896917448 hasConcept C126322002 @default.
- W2896917448 hasConcept C142724271 @default.
- W2896917448 hasConcept C168563851 @default.
- W2896917448 hasConcept C203092338 @default.
- W2896917448 hasConcept C204787440 @default.
- W2896917448 hasConcept C27081682 @default.
- W2896917448 hasConcept C2778589496 @default.
- W2896917448 hasConcept C2780400711 @default.
- W2896917448 hasConcept C2780739214 @default.
- W2896917448 hasConcept C45393284 @default.
- W2896917448 hasConcept C500558357 @default.
- W2896917448 hasConcept C71924100 @default.
- W2896917448 hasConcept C90924648 @default.
- W2896917448 hasConceptScore W2896917448C126322002 @default.
- W2896917448 hasConceptScore W2896917448C142724271 @default.
- W2896917448 hasConceptScore W2896917448C168563851 @default.
- W2896917448 hasConceptScore W2896917448C203092338 @default.
- W2896917448 hasConceptScore W2896917448C204787440 @default.
- W2896917448 hasConceptScore W2896917448C27081682 @default.
- W2896917448 hasConceptScore W2896917448C2778589496 @default.
- W2896917448 hasConceptScore W2896917448C2780400711 @default.
- W2896917448 hasConceptScore W2896917448C2780739214 @default.
- W2896917448 hasConceptScore W2896917448C45393284 @default.
- W2896917448 hasConceptScore W2896917448C500558357 @default.
- W2896917448 hasConceptScore W2896917448C71924100 @default.
- W2896917448 hasConceptScore W2896917448C90924648 @default.
- W2896917448 hasFunder F4320325902 @default.
- W2896917448 hasLocation W28969174481 @default.
- W2896917448 hasLocation W28969174482 @default.
- W2896917448 hasLocation W28969174483 @default.
- W2896917448 hasLocation W28969174484 @default.
- W2896917448 hasLocation W28969174485 @default.
- W2896917448 hasOpenAccess W2896917448 @default.
- W2896917448 hasPrimaryLocation W28969174481 @default.
- W2896917448 hasRelatedWork W2373440156 @default.
- W2896917448 hasRelatedWork W2530212111 @default.
- W2896917448 hasRelatedWork W2625296372 @default.
- W2896917448 hasRelatedWork W2822274293 @default.
- W2896917448 hasRelatedWork W2896917448 @default.
- W2896917448 hasRelatedWork W2908422030 @default.
- W2896917448 hasRelatedWork W2972257398 @default.
- W2896917448 hasRelatedWork W3096524966 @default.
- W2896917448 hasRelatedWork W3197198654 @default.
- W2896917448 hasRelatedWork W3212500004 @default.
- W2896917448 isParatext "false" @default.
- W2896917448 isRetracted "false" @default.
- W2896917448 magId "2896917448" @default.
- W2896917448 workType "article" @default.