FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896929243> ?p ?o ?g. }

• W2896929243 endingPage "252" @default.
• W2896929243 startingPage "244" @default.
• W2896929243 abstract "A constitutively increased intracellular pH that is higher than the extracellular pH is emerging as a hallmark of cancer and determining pH could play a significant role in the measurement of drug responsiveness of tumor cells. However, a non-invasive, touch-free and real-time pH sensing as a research tool is lacking and remains a major unmet need. The purpose of the current study is to investigate a microfluidic surface acoustic wave (SAW) sensor platform capable of monitoring pH in cell and tumoroid cultures. A novel multi-layer guided SAW sensor integrated into a microfluidic channel was investigated theoretically and experimentally in detail for pH bio-sensing. Sensitivity and capability of the layer guided Love wave device was modeled using the finite element simulation. The model was verified experimentally, and a study monitoring pH of cell growth media is presented. This novel pH sensor is based on a 13.91 MHz center frequency SAW device coated with ZnO (500 nm) and IrO2 (30 nm) layers to increase the sensitivity. A change in mechanical and electrical properties of the conductive IrO2 layer was observed resulting from electrical corrosion induced by pH solutions affecting the charge distribution, SAW phase velocity and attenuation. By measuring the frequency shift induced by the change in SAW phase velocity between the test group and control group, the pH value of cell culture media from H460 cancer cell culture plates from day 0 to day 5 can easily be determined. To improve the sensitivity and stability of the sensor, a finite element method was used to optimize the layer thicknesses. Taken together, the results of experiments show the potential application of this device to be integrated with microfluidic channels and used in determining pH changes in longitudinal tumor cell cultures." @default.
• W2896929243 created "2018-10-26" @default.
• W2896929243 creator A5010321945 @default.
• W2896929243 creator A5070034685 @default.
• W2896929243 creator A5083340498 @default.
• W2896929243 creator A5085142676 @default.
• W2896929243 creator A5089465392 @default.
• W2896929243 date "2019-01-01" @default.
• W2896929243 modified "2023-09-26" @default.
• W2896929243 title "Multiple-layer guided surface acoustic wave (SAW)-based pH sensing in longitudinal FiSS-tumoroid cultures" @default.
• W2896929243 cites W1485712338 @default.
• W2896929243 cites W1486200716 @default.
• W2896929243 cites W1972399155 @default.
• W2896929243 cites W1976564797 @default.
• W2896929243 cites W1981721404 @default.
• W2896929243 cites W1983231076 @default.
• W2896929243 cites W1984716179 @default.
• W2896929243 cites W1985690701 @default.
• W2896929243 cites W1987060662 @default.
• W2896929243 cites W1995444593 @default.
• W2896929243 cites W1998952050 @default.
• W2896929243 cites W2008117805 @default.
• W2896929243 cites W2021242247 @default.
• W2896929243 cites W2027156888 @default.
• W2896929243 cites W2031591190 @default.
• W2896929243 cites W2032977533 @default.
• W2896929243 cites W2042321308 @default.
• W2896929243 cites W2045976423 @default.
• W2896929243 cites W2049007853 @default.
• W2896929243 cites W2059563071 @default.
• W2896929243 cites W2062099328 @default.
• W2896929243 cites W2064125839 @default.
• W2896929243 cites W2065376967 @default.
• W2896929243 cites W2075337132 @default.
• W2896929243 cites W2080791075 @default.
• W2896929243 cites W2084441235 @default.
• W2896929243 cites W2087054077 @default.
• W2896929243 cites W2088728276 @default.
• W2896929243 cites W2091695437 @default.
• W2896929243 cites W2095169603 @default.
• W2896929243 cites W2113447668 @default.
• W2896929243 cites W2114853463 @default.
• W2896929243 cites W2122510170 @default.
• W2896929243 cites W2130390753 @default.
• W2896929243 cites W2131268289 @default.
• W2896929243 cites W2131836341 @default.
• W2896929243 cites W2137675565 @default.
• W2896929243 cites W2137780153 @default.
• W2896929243 cites W2169232755 @default.
• W2896929243 cites W2260783929 @default.
• W2896929243 cites W2323408342 @default.
• W2896929243 cites W2323599230 @default.
• W2896929243 cites W2514596504 @default.
• W2896929243 cites W2585117708 @default.
• W2896929243 cites W2608944412 @default.
• W2896929243 cites W2746313687 @default.
• W2896929243 cites W2767702933 @default.
• W2896929243 cites W2775189426 @default.
• W2896929243 doi "https://doi.org/10.1016/j.bios.2018.10.011" @default.
• W2896929243 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30390467" @default.
• W2896929243 hasPublicationYear "2019" @default.
• W2896929243 type Work @default.
• W2896929243 sameAs 2896929243 @default.
• W2896929243 citedByCount "15" @default.
• W2896929243 countsByYear W28969292432019 @default.
• W2896929243 countsByYear W28969292432020 @default.
• W2896929243 countsByYear W28969292432021 @default.
• W2896929243 countsByYear W28969292432022 @default.
• W2896929243 countsByYear W28969292432023 @default.
• W2896929243 crossrefType "journal-article" @default.
• W2896929243 hasAuthorship W2896929243A5010321945 @default.
• W2896929243 hasAuthorship W2896929243A5070034685 @default.
• W2896929243 hasAuthorship W2896929243A5083340498 @default.
• W2896929243 hasAuthorship W2896929243A5085142676 @default.
• W2896929243 hasAuthorship W2896929243A5089465392 @default.
• W2896929243 hasConcept C120665830 @default.
• W2896929243 hasConcept C121332964 @default.
• W2896929243 hasConcept C127413603 @default.
• W2896929243 hasConcept C135628077 @default.
• W2896929243 hasConcept C159985019 @default.
• W2896929243 hasConcept C162954803 @default.
• W2896929243 hasConcept C171250308 @default.
• W2896929243 hasConcept C184652730 @default.
• W2896929243 hasConcept C192562407 @default.
• W2896929243 hasConcept C201645281 @default.
• W2896929243 hasConcept C202374169 @default.
• W2896929243 hasConcept C21200559 @default.
• W2896929243 hasConcept C24326235 @default.
• W2896929243 hasConcept C24890656 @default.
• W2896929243 hasConcept C2779227376 @default.
• W2896929243 hasConcept C49040817 @default.
• W2896929243 hasConcept C8673954 @default.
• W2896929243 hasConcept C97355855 @default.
• W2896929243 hasConceptScore W2896929243C120665830 @default.
• W2896929243 hasConceptScore W2896929243C121332964 @default.
• W2896929243 hasConceptScore W2896929243C127413603 @default.
• W2896929243 hasConceptScore W2896929243C135628077 @default.
• W2896929243 hasConceptScore W2896929243C159985019 @default.

• next