Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896937577> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2896937577 abstract "8-Nitroguanosine 3',5'-cyclic monophosphate (8-nitro-cGMP), which is the second messenger in nitric oxide/reactive oxygen species redox signaling, covalently binds to protein thiol groups (called S-guanylation) and exerts various biological functions. Synaptosomal associated protein 25 (SNAP-25), a member of soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins, plays an important role in the process of membrane fusion. We previously showed that SNAP-25 is S-guanylated at cysteine 90. In addition, we revealed that S-guanylation of SNAP-25 increases SNARE complex formation, but decreases the affinity of SNARE complex for complexin. Since SNAP-25 plays a critical role in regulating exocytosis, it is important to elucidate the physiological or pathophysiological meanings of S-guanylation of this protein. Here we describe a protocol for detecting 8-nitro-cGMP and S-guanylated proteins in cells by immunocytochemistry, and methods to detect SNARE complex in 8-nitro-cGMP-treated cells." @default.
- W2896937577 created "2018-10-26" @default.
- W2896937577 creator A5002310524 @default.
- W2896937577 creator A5007672008 @default.
- W2896937577 creator A5072183453 @default.
- W2896937577 date "2018-10-14" @default.
- W2896937577 modified "2023-09-23" @default.
- W2896937577 title "SNAP-25 S-Guanylation and SNARE Complex Formation" @default.
- W2896937577 cites W1067583755 @default.
- W2896937577 cites W1500769740 @default.
- W2896937577 cites W2005432117 @default.
- W2896937577 cites W2024160713 @default.
- W2896937577 cites W2048465987 @default.
- W2896937577 cites W2068119233 @default.
- W2896937577 cites W2071963097 @default.
- W2896937577 cites W2083875917 @default.
- W2896937577 cites W2127061791 @default.
- W2896937577 cites W2155314275 @default.
- W2896937577 cites W2292175535 @default.
- W2896937577 cites W2297739758 @default.
- W2896937577 cites W2767974741 @default.
- W2896937577 cites W2748620112 @default.
- W2896937577 doi "https://doi.org/10.1007/978-1-4939-8760-3_9" @default.
- W2896937577 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30317503" @default.
- W2896937577 hasPublicationYear "2018" @default.
- W2896937577 type Work @default.
- W2896937577 sameAs 2896937577 @default.
- W2896937577 citedByCount "0" @default.
- W2896937577 crossrefType "book-chapter" @default.
- W2896937577 hasAuthorship W2896937577A5002310524 @default.
- W2896937577 hasAuthorship W2896937577A5007672008 @default.
- W2896937577 hasAuthorship W2896937577A5072183453 @default.
- W2896937577 hasConcept C103038307 @default.
- W2896937577 hasConcept C121684516 @default.
- W2896937577 hasConcept C175969161 @default.
- W2896937577 hasConcept C178790620 @default.
- W2896937577 hasConcept C181199279 @default.
- W2896937577 hasConcept C185592680 @default.
- W2896937577 hasConcept C2779201268 @default.
- W2896937577 hasConcept C2779997099 @default.
- W2896937577 hasConcept C2908790754 @default.
- W2896937577 hasConcept C41008148 @default.
- W2896937577 hasConcept C41625074 @default.
- W2896937577 hasConcept C519581460 @default.
- W2896937577 hasConcept C55493867 @default.
- W2896937577 hasConcept C86803240 @default.
- W2896937577 hasConcept C95444343 @default.
- W2896937577 hasConceptScore W2896937577C103038307 @default.
- W2896937577 hasConceptScore W2896937577C121684516 @default.
- W2896937577 hasConceptScore W2896937577C175969161 @default.
- W2896937577 hasConceptScore W2896937577C178790620 @default.
- W2896937577 hasConceptScore W2896937577C181199279 @default.
- W2896937577 hasConceptScore W2896937577C185592680 @default.
- W2896937577 hasConceptScore W2896937577C2779201268 @default.
- W2896937577 hasConceptScore W2896937577C2779997099 @default.
- W2896937577 hasConceptScore W2896937577C2908790754 @default.
- W2896937577 hasConceptScore W2896937577C41008148 @default.
- W2896937577 hasConceptScore W2896937577C41625074 @default.
- W2896937577 hasConceptScore W2896937577C519581460 @default.
- W2896937577 hasConceptScore W2896937577C55493867 @default.
- W2896937577 hasConceptScore W2896937577C86803240 @default.
- W2896937577 hasConceptScore W2896937577C95444343 @default.
- W2896937577 hasLocation W28969375771 @default.
- W2896937577 hasLocation W28969375772 @default.
- W2896937577 hasOpenAccess W2896937577 @default.
- W2896937577 hasPrimaryLocation W28969375771 @default.
- W2896937577 hasRelatedWork W1981711363 @default.
- W2896937577 hasRelatedWork W2019681946 @default.
- W2896937577 hasRelatedWork W2039644903 @default.
- W2896937577 hasRelatedWork W2042332532 @default.
- W2896937577 hasRelatedWork W2081158331 @default.
- W2896937577 hasRelatedWork W2124984913 @default.
- W2896937577 hasRelatedWork W2142952771 @default.
- W2896937577 hasRelatedWork W2147169289 @default.
- W2896937577 hasRelatedWork W2149231882 @default.
- W2896937577 hasRelatedWork W2584098703 @default.
- W2896937577 isParatext "false" @default.
- W2896937577 isRetracted "false" @default.
- W2896937577 magId "2896937577" @default.
- W2896937577 workType "book-chapter" @default.