FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896938242> ?p ?o ?g. }

• W2896938242 endingPage "1002" @default.
• W2896938242 startingPage "993" @default.
• W2896938242 abstract "Abstract Background Serum folate forms, and particularly tetrahydrofolate, are sensitive to oxidation. Methods Using a repeated measures design, we investigated the stability of folate forms in convenience samples with added ascorbic acid (AA; 5 g/L) analyzed initially and after variable (approximately 1–33 weeks) storage time at −70 °C. We examined the recovery of tetrahydrofolate added at different spiking levels to serum with and without AA (5 g/L). We also assessed the long-term frozen storage stability of folate forms. Results Repeat analysis produced consistent results with the initial analysis; the mean relative change (95% CI; Lin's concordance correlation between initial and repeat result; sample size) was 0.08% (−0.24% to 0.39%; r c = 0.999; n = 301) for 5-methyltetrahydrofolate, 4.23% (2.44%–6.05%; r c = 0.984; n = 211) for pyrazino-s-triazine derivative of 4α-hydroxy-5-methyltetrahydrofolate (MeFox), −0.22% (−1.90% to 1.49%; r c = 0.986; n = 214) for folic acid, and 1.49% (−2.71% to 5.88%; r c = 0.889; n = 81) for tetrahydrofolate. Linear regression testing for a time trend indicated an estimated average percent change of less than ±5% for samples retested after 4 months: 5-methyltetrahydrofolate P trend = 0.0007, folic acid P trend &lt; 0.0001, MeFox P trend = 0.38, and tetrahydrofolate P trend = 0.0256. The mean ± SD tetrahydrofolate spiking recovery was 96.7% ± 9.4% for serum with added AA, but &lt;50% for serum without added AA. We observed ≤10% loss for most serum folate forms during 4 years of storage at −70 °C. Conclusions Serum containing added AA showed acceptable stability of folate forms during repeat analysis from the same vial within 4 months, complete spiking recovery of tetrahydrofolate during sample processing, and long-term frozen storage stability of folate forms." @default.
• W2896938242 created "2018-10-26" @default.
• W2896938242 creator A5009760950 @default.
• W2896938242 creator A5028849078 @default.
• W2896938242 creator A5037616130 @default.
• W2896938242 creator A5038235490 @default.
• W2896938242 creator A5088286604 @default.
• W2896938242 date "2019-05-01" @default.
• W2896938242 modified "2023-09-27" @default.
• W2896938242 title "Serum Folate Forms Are Stable during Repeated Analysis in the Presence of Ascorbic Acid and during Frozen Sample Storage" @default.
• W2896938242 cites W1558552946 @default.
• W2896938242 cites W2018319907 @default.
• W2896938242 cites W2062186197 @default.
• W2896938242 cites W2071208072 @default.
• W2896938242 cites W2081981514 @default.
• W2896938242 cites W2095295126 @default.
• W2896938242 cites W2113944997 @default.
• W2896938242 cites W2150910607 @default.
• W2896938242 cites W2171585880 @default.
• W2896938242 cites W2313339984 @default.
• W2896938242 cites W2327777483 @default.
• W2896938242 cites W4234155465 @default.
• W2896938242 doi "https://doi.org/10.1373/jalm.2018.027102" @default.
• W2896938242 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7263443" @default.
• W2896938242 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31639690" @default.
• W2896938242 hasPublicationYear "2019" @default.
• W2896938242 type Work @default.
• W2896938242 sameAs 2896938242 @default.
• W2896938242 citedByCount "3" @default.
• W2896938242 countsByYear W28969382422019 @default.
• W2896938242 countsByYear W28969382422022 @default.
• W2896938242 countsByYear W28969382422023 @default.
• W2896938242 crossrefType "journal-article" @default.
• W2896938242 hasAuthorship W2896938242A5009760950 @default.
• W2896938242 hasAuthorship W2896938242A5028849078 @default.
• W2896938242 hasAuthorship W2896938242A5037616130 @default.
• W2896938242 hasAuthorship W2896938242A5038235490 @default.
• W2896938242 hasAuthorship W2896938242A5088286604 @default.
• W2896938242 hasBestOaLocation W28969382422 @default.
• W2896938242 hasConcept C126322002 @default.
• W2896938242 hasConcept C140793950 @default.
• W2896938242 hasConcept C160798450 @default.
• W2896938242 hasConcept C185592680 @default.
• W2896938242 hasConcept C2986274086 @default.
• W2896938242 hasConcept C2992130864 @default.
• W2896938242 hasConcept C31903555 @default.
• W2896938242 hasConcept C55493867 @default.
• W2896938242 hasConcept C71924100 @default.
• W2896938242 hasConcept C86803240 @default.
• W2896938242 hasConceptScore W2896938242C126322002 @default.
• W2896938242 hasConceptScore W2896938242C140793950 @default.
• W2896938242 hasConceptScore W2896938242C160798450 @default.
• W2896938242 hasConceptScore W2896938242C185592680 @default.
• W2896938242 hasConceptScore W2896938242C2986274086 @default.
• W2896938242 hasConceptScore W2896938242C2992130864 @default.
• W2896938242 hasConceptScore W2896938242C31903555 @default.
• W2896938242 hasConceptScore W2896938242C55493867 @default.
• W2896938242 hasConceptScore W2896938242C71924100 @default.
• W2896938242 hasConceptScore W2896938242C86803240 @default.
• W2896938242 hasIssue "6" @default.
• W2896938242 hasLocation W28969382421 @default.
• W2896938242 hasLocation W28969382422 @default.
• W2896938242 hasLocation W28969382423 @default.
• W2896938242 hasOpenAccess W2896938242 @default.
• W2896938242 hasPrimaryLocation W28969382421 @default.
• W2896938242 hasRelatedWork W1976580711 @default.
• W2896938242 hasRelatedWork W2011531053 @default.
• W2896938242 hasRelatedWork W2062114946 @default.
• W2896938242 hasRelatedWork W2147256274 @default.
• W2896938242 hasRelatedWork W2950666140 @default.
• W2896938242 hasRelatedWork W2950912390 @default.
• W2896938242 hasRelatedWork W2950968125 @default.
• W2896938242 hasRelatedWork W2951202326 @default.
• W2896938242 hasRelatedWork W2951287109 @default.
• W2896938242 hasRelatedWork W2951760521 @default.
• W2896938242 hasVolume "3" @default.
• W2896938242 isParatext "false" @default.
• W2896938242 isRetracted "false" @default.
• W2896938242 magId "2896938242" @default.
• W2896938242 workType "article" @default.