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- W2896942006 abstract "Application: The Radioisotope Iodine-125 has rather long half-life, and high dose range of Gamma radiation. It will be used in two cases,in our radioisotope production department: 1-To label Radioimmunoassay Kits (RIA): T3, T4 and TSH for IN{sub V}ITRO investigation of Thyroid glands, in our Nuclear Medical Center in IRAN. We just started to set up Hot cell facilities and in cell equipment to supply Iodine-125 for our Radioimmunoassay Group.In this section. The above Iodine-125 will be used for labelling of their Radioimmunoassay products for Thyroid functions and also for screening of newborns for Thyroid deficiency. 2-We have also just start, the make and supply particular granules of Iodine-125 by Silver coated Iodine-125 directly and also indirectly, on the Palladium, coated Silver Wire to be used in Brachytherapy applications. Production: After filling Target with 15 g of natural Xe gas by excellent technology and closed in leak-tight allowing reactor irradiation. The target is irradiated in a nuclear reactor for 3 weeks optimally at a thermal neutron flux around {phi}= 1*10{sup 14} n.cm{sup -2}.s{sup -1}.After transferring irradiated target to hot cell, The aluminium capsule is opened by putting it into the punching apparatus and pushing the needle into the bottom of the aluminium capsule by turning the handle counter-clockwise. When the needle punches the aluminium. The Xe gas is released into the chimney and the I-125 radioisotope is adsorbed on the inside wall of the aluminium capsule. After this the opened aluminium capsule is pulled off from the needle by turning the handle clockwise. The opened capsule is ready to distillation. Preparation of the distillation oven and equipment: on the first occasion the oven should be heated two-times up to 550 {sup o}C for two hours each to eliminate potential contamination. After it the radioactive aluminium capsule is put into the oven and vacuum is started. This is followed by switching on the heating. The distillation is followed through 120 minutes at a temperature of 550 {sup o}C. Solutions of the required radioactive concentration are dispensed to portions into ampoules. If sterile product is required ampoules should be autoclaved for 30 minutes at a temperature of 120 {sup o}C. (author)" @default.
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- W2896942006 date "2006-01-01" @default.
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- W2896942006 title "Production of I-125 radioisotope in sodium iodide solution" @default.
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