Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896943746> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2896943746 endingPage "5" @default.
- W2896943746 startingPage "1" @default.
- W2896943746 abstract "Background and Objective . Evidence for the roles of matrix metalloproteinases-9 (MMP-9) in the healing process of diabetic foot ulcers has remained unclear. We therefore aimed to demonstrate the relationship of MMP-9 with the wound healing process and determine its potential usefulness in predicting the wound healing outcome. Methods . Twenty-two patients with diabetic foot ulcer were recruited. The wound size was determined, and the wound fluid was collected for the measurement of MMP-9 levels using an ELISA during the 12-week follow-up period regularly. The patients were categorized as good healers and poor healers when the wound area reduction was ≥ 50% and < 50% at week 4 when compared to the initial wound size at week 0. Results . Median wound fluid MMP-9 levels in the poor healer group were shown to be significantly higher than those in the good healer group (1.03 pg/ µ g protein vs. 0.06 pg/ µ g protein, p = 0.001), and the levels fluctuated throughout the 12-week follow-up period. In contrast to the poor healer group, the MMP-9 levels were demonstrated to be constantly low throughout the follow-up period in the good healer group. ROC analysis showed that the MMP-9 level of 0.38 pg/ µ g protein was able to predict the wound healing outcome with the sensitivity of 81.8%, the specificity of 64.6%, and the area under the curve of 0.901 (CI 0.78-1.03, p = 0.001). Conclusion . These findings suggested that determination of wound fluid MMP-9 levels might become a promising biomarker predicting wound healing outcomes and a novel potential therapeutic target for diabetic foot ulcers." @default.
- W2896943746 created "2018-10-26" @default.
- W2896943746 creator A5011859300 @default.
- W2896943746 creator A5018230013 @default.
- W2896943746 creator A5032639031 @default.
- W2896943746 creator A5035728247 @default.
- W2896943746 creator A5077066517 @default.
- W2896943746 date "2018-10-16" @default.
- W2896943746 modified "2023-10-11" @default.
- W2896943746 title "Wound Fluid Matrix Metalloproteinase-9 as a Potential Predictive Marker for the Poor Healing Outcome in Diabetic Foot Ulcers" @default.
- W2896943746 cites W1964970181 @default.
- W2896943746 cites W1976528260 @default.
- W2896943746 cites W1976780309 @default.
- W2896943746 cites W1980363157 @default.
- W2896943746 cites W1980923037 @default.
- W2896943746 cites W1988354642 @default.
- W2896943746 cites W2017862021 @default.
- W2896943746 cites W2019109370 @default.
- W2896943746 cites W2033667314 @default.
- W2896943746 cites W2047960744 @default.
- W2896943746 cites W2056706192 @default.
- W2896943746 cites W2061992885 @default.
- W2896943746 cites W2069157301 @default.
- W2896943746 cites W2071534864 @default.
- W2896943746 cites W2082941476 @default.
- W2896943746 cites W2099743114 @default.
- W2896943746 cites W2111189753 @default.
- W2896943746 cites W2153323181 @default.
- W2896943746 cites W2462069432 @default.
- W2896943746 cites W4236456175 @default.
- W2896943746 cites W4250908540 @default.
- W2896943746 doi "https://doi.org/10.1155/2018/1631325" @default.
- W2896943746 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6206565" @default.
- W2896943746 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30410716" @default.
- W2896943746 hasPublicationYear "2018" @default.
- W2896943746 type Work @default.
- W2896943746 sameAs 2896943746 @default.
- W2896943746 citedByCount "19" @default.
- W2896943746 countsByYear W28969437462019 @default.
- W2896943746 countsByYear W28969437462020 @default.
- W2896943746 countsByYear W28969437462021 @default.
- W2896943746 countsByYear W28969437462022 @default.
- W2896943746 countsByYear W28969437462023 @default.
- W2896943746 crossrefType "journal-article" @default.
- W2896943746 hasAuthorship W2896943746A5011859300 @default.
- W2896943746 hasAuthorship W2896943746A5018230013 @default.
- W2896943746 hasAuthorship W2896943746A5032639031 @default.
- W2896943746 hasAuthorship W2896943746A5035728247 @default.
- W2896943746 hasAuthorship W2896943746A5077066517 @default.
- W2896943746 hasBestOaLocation W28969437461 @default.
- W2896943746 hasConcept C109523444 @default.
- W2896943746 hasConcept C126322002 @default.
- W2896943746 hasConcept C134018914 @default.
- W2896943746 hasConcept C141071460 @default.
- W2896943746 hasConcept C2777858829 @default.
- W2896943746 hasConcept C2778144972 @default.
- W2896943746 hasConcept C2780269544 @default.
- W2896943746 hasConcept C555293320 @default.
- W2896943746 hasConcept C71924100 @default.
- W2896943746 hasConcept C90924648 @default.
- W2896943746 hasConceptScore W2896943746C109523444 @default.
- W2896943746 hasConceptScore W2896943746C126322002 @default.
- W2896943746 hasConceptScore W2896943746C134018914 @default.
- W2896943746 hasConceptScore W2896943746C141071460 @default.
- W2896943746 hasConceptScore W2896943746C2777858829 @default.
- W2896943746 hasConceptScore W2896943746C2778144972 @default.
- W2896943746 hasConceptScore W2896943746C2780269544 @default.
- W2896943746 hasConceptScore W2896943746C555293320 @default.
- W2896943746 hasConceptScore W2896943746C71924100 @default.
- W2896943746 hasConceptScore W2896943746C90924648 @default.
- W2896943746 hasLocation W28969437461 @default.
- W2896943746 hasLocation W28969437462 @default.
- W2896943746 hasLocation W28969437463 @default.
- W2896943746 hasLocation W28969437464 @default.
- W2896943746 hasOpenAccess W2896943746 @default.
- W2896943746 hasPrimaryLocation W28969437461 @default.
- W2896943746 hasRelatedWork W2140779700 @default.
- W2896943746 hasRelatedWork W2302858471 @default.
- W2896943746 hasRelatedWork W2329712847 @default.
- W2896943746 hasRelatedWork W2400134899 @default.
- W2896943746 hasRelatedWork W2763046336 @default.
- W2896943746 hasRelatedWork W2904963997 @default.
- W2896943746 hasRelatedWork W2982199195 @default.
- W2896943746 hasRelatedWork W3039894954 @default.
- W2896943746 hasRelatedWork W3046011215 @default.
- W2896943746 hasRelatedWork W4220938004 @default.
- W2896943746 hasVolume "2018" @default.
- W2896943746 isParatext "false" @default.
- W2896943746 isRetracted "false" @default.
- W2896943746 magId "2896943746" @default.
- W2896943746 workType "article" @default.