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- W2896952085 abstract "To compare the clinical features of fetuses with Ebstein anomaly (EA) and pulmonary atresia with intact ventricular septum (PA IVS). All fetuses that were prenatally diagnosed as EA or PA IVS were retrospectively reviewed between January 2007 and December 2016 at Asan Medical Centre. Among cases of prenatally diagnosed EA, 44 cases had confirmative diagnosis. Thirty-one cases were postnatally confirmed as EA and 13 cases were diagnosed as other diseases, including 7 cases of PA IVS. Survival rate of postnatally confirmed EA were 67.7%. Significant negative prognostic factors for survival were presence of fetal distress, preterm delivery, increased CT ratio, absent pulmonary forward flow with retrograde flow form ductus arteriosus, presence of pulmonary valve regurgitation, and associated fetal hydrops. During the same period, 82 cases of PA IVS were prenatally diagnosed and 78 cases had final diagnosis. Among them, 56 cases were postnatally confirmed as PA IVS and 22 cases were diagnosed as other diseases, including 10 cases of EA and 9 cases of critical pulmonary stenosis. Survival rate of postnatally confirmed PA IVS were 83.9%. Significant negative prognostic factors were presence of fetal distress, preterm birth, cardiomegaly, and increased CT ratio. There were another 16 fetuses who demonstrated severe tricuspid valve (TV) regurgitation with RA enlargement, and therefore, it was difficult to differentiate between the two diseases. Postnatally, 9 cases of EA, 5 cases of PA IVS, and 2 cases of EA combined with PA IVS were confirmed. There was no significant difference in prenatal echocardiographic findings including offset distance of the tricuspid septal leaflet, TV Z-score, and RV/LV length ratio between 9 cases of EA and 5 cases of PA IVS. EA and PA IVS have different clinical manifestation, and therefore, accurate prenatal diagnosis and counselling are important. Because it is difficult to differentiate between two diseases in advanced stage, earlier prenatal diagnosis is crucial." @default.
- W2896952085 created "2018-10-26" @default.
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- W2896952085 date "2018-10-01" @default.
- W2896952085 modified "2023-10-18" @default.
- W2896952085 title "OC11.05: Comparison of clinical manifestation in fetuses with Ebstein's anomaly and pulmonary atresia with intact ventricular septum" @default.
- W2896952085 doi "https://doi.org/10.1002/uog.19278" @default.
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