FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896955691> ?p ?o ?g. }

• W2896955691 endingPage "e0205271" @default.
• W2896955691 startingPage "e0205271" @default.
• W2896955691 abstract "Objectives and study This study aimed at measuring the effect in normal to restricted protein diets with specific 15N natural isotopic abundance (NIA) given during gestation and/or lactation on the 15N NIA of fur, liver and muscle in dams and their offspring from birth to adulthood. The secondary aim was to study the effect of growth on the same parameters. Methods Female Balb/c mice were fed normal protein diet containing 22% protein or isocaloric low protein diet containing 10% protein throughout gestation. Dam’s diets were either maintained or switched to the other diet until weaning at 30 days. All animals were fed standard chow thereafter. Offspring were sacrificed at 1, 11, 30, 60, 480 days and a group of dams at d1. Growth was modeled as an exponential function on the group followed up until 480 days. Fur, liver and muscle were sampled at sacrifice and analyzed for bulk 15N NIA. Fixed effects and interactions between fixed effects and random elements were tested by three-way ANOVA. Results Higher 15N NIA in the diet resulted in higher organ 15N NIA. Switching from one diet to another changed 15N NIA in each organ. Although dam and offspring shared the same isotopic environment during gestation, 15N NIA at day 1 was higher in dams. Growth rate did not differ between groups after 10 days and decreased between 1 and 5 months. 15N NIA differed between organs and was affected by growth and gestation/lactation. Conclusion Dietary 15N NIA is a major determinant of the 15N NIA of organs. 15N NIA depended on organ and age (i.e. growth) suggesting an effect of metabolism and/or dilution space. Post-natal normal-protein diet of lactating dams could reverse the effect of a protein-restricted diet during gestation on the offspring growth. Measuring 15N NIA in various matrices may open a field of application particularly useful in studying the pre- and post-natal origins of health and disease." @default.
• W2896955691 created "2018-10-26" @default.
• W2896955691 creator A5004908015 @default.
• W2896955691 creator A5005654150 @default.
• W2896955691 creator A5010424010 @default.
• W2896955691 creator A5024622355 @default.
• W2896955691 creator A5042087350 @default.
• W2896955691 creator A5058085217 @default.
• W2896955691 creator A5062676534 @default.
• W2896955691 creator A5088711188 @default.
• W2896955691 date "2018-10-10" @default.
• W2896955691 modified "2023-10-11" @default.
• W2896955691 title "Protein restricted diet during gestation and/or lactation in mice affects 15N natural isotopic abundance of organs in the offspring: Effect of diet 15N content and growth" @default.
• W2896955691 cites W1930261679 @default.
• W2896955691 cites W1971986373 @default.
• W2896955691 cites W1987196911 @default.
• W2896955691 cites W2015000855 @default.
• W2896955691 cites W2035590031 @default.
• W2896955691 cites W2048003222 @default.
• W2896955691 cites W2063020698 @default.
• W2896955691 cites W2079973462 @default.
• W2896955691 cites W2081054022 @default.
• W2896955691 cites W2084840364 @default.
• W2896955691 cites W2125655344 @default.
• W2896955691 cites W2132051878 @default.
• W2896955691 cites W2143230895 @default.
• W2896955691 cites W2149623467 @default.
• W2896955691 cites W2160843938 @default.
• W2896955691 cites W2166788616 @default.
• W2896955691 cites W2271963502 @default.
• W2896955691 cites W2318907435 @default.
• W2896955691 cites W2413308684 @default.
• W2896955691 cites W2792002308 @default.
• W2896955691 cites W90239176 @default.
• W2896955691 doi "https://doi.org/10.1371/journal.pone.0205271" @default.
• W2896955691 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6179277" @default.
• W2896955691 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30304003" @default.
• W2896955691 hasPublicationYear "2018" @default.
• W2896955691 type Work @default.
• W2896955691 sameAs 2896955691 @default.
• W2896955691 citedByCount "3" @default.
• W2896955691 countsByYear W28969556912020 @default.
• W2896955691 countsByYear W28969556912021 @default.
• W2896955691 countsByYear W28969556912022 @default.
• W2896955691 crossrefType "journal-article" @default.
• W2896955691 hasAuthorship W2896955691A5004908015 @default.
• W2896955691 hasAuthorship W2896955691A5005654150 @default.
• W2896955691 hasAuthorship W2896955691A5010424010 @default.
• W2896955691 hasAuthorship W2896955691A5024622355 @default.
• W2896955691 hasAuthorship W2896955691A5042087350 @default.
• W2896955691 hasAuthorship W2896955691A5058085217 @default.
• W2896955691 hasAuthorship W2896955691A5062676534 @default.
• W2896955691 hasAuthorship W2896955691A5088711188 @default.
• W2896955691 hasBestOaLocation W28969556911 @default.
• W2896955691 hasConcept C112672928 @default.
• W2896955691 hasConcept C126322002 @default.
• W2896955691 hasConcept C134018914 @default.
• W2896955691 hasConcept C140793950 @default.
• W2896955691 hasConcept C2776659692 @default.
• W2896955691 hasConcept C2779234561 @default.
• W2896955691 hasConcept C2780655333 @default.
• W2896955691 hasConcept C46973012 @default.
• W2896955691 hasConcept C54355233 @default.
• W2896955691 hasConcept C71924100 @default.
• W2896955691 hasConcept C86803240 @default.
• W2896955691 hasConceptScore W2896955691C112672928 @default.
• W2896955691 hasConceptScore W2896955691C126322002 @default.
• W2896955691 hasConceptScore W2896955691C134018914 @default.
• W2896955691 hasConceptScore W2896955691C140793950 @default.
• W2896955691 hasConceptScore W2896955691C2776659692 @default.
• W2896955691 hasConceptScore W2896955691C2779234561 @default.
• W2896955691 hasConceptScore W2896955691C2780655333 @default.
• W2896955691 hasConceptScore W2896955691C46973012 @default.
• W2896955691 hasConceptScore W2896955691C54355233 @default.
• W2896955691 hasConceptScore W2896955691C71924100 @default.
• W2896955691 hasConceptScore W2896955691C86803240 @default.
• W2896955691 hasFunder F4320325507 @default.
• W2896955691 hasIssue "10" @default.
• W2896955691 hasLocation W28969556911 @default.
• W2896955691 hasLocation W28969556912 @default.
• W2896955691 hasLocation W28969556913 @default.
• W2896955691 hasLocation W28969556914 @default.
• W2896955691 hasLocation W28969556915 @default.
• W2896955691 hasLocation W28969556916 @default.
• W2896955691 hasLocation W28969556917 @default.
• W2896955691 hasLocation W28969556918 @default.
• W2896955691 hasOpenAccess W2896955691 @default.
• W2896955691 hasPrimaryLocation W28969556911 @default.
• W2896955691 hasRelatedWork W163016992 @default.
• W2896955691 hasRelatedWork W1979105721 @default.
• W2896955691 hasRelatedWork W1984669348 @default.
• W2896955691 hasRelatedWork W1996322489 @default.
• W2896955691 hasRelatedWork W2016258313 @default.
• W2896955691 hasRelatedWork W2044398732 @default.
• W2896955691 hasRelatedWork W2080340812 @default.
• W2896955691 hasRelatedWork W2409383815 @default.
• W2896955691 hasRelatedWork W2496469184 @default.
• W2896955691 hasRelatedWork W2898376424 @default.

• next