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• W2896960889 abstract "In the present study geraniol at the final concentration of 10, 20, 30, and 40 µM was mixed in the diet along with 80 µM of arecoline and the third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ) Bg9 were allowed to feed on it for 24 hrs. After the exposure of 24 hrs the larvae were subjected to ONPG, X-gal, trypan blue exclusion test, oxidative stress markers and apoptotic and comet assays. The exposure of larvae to geraniol showed a dose dependent decrease in the activity of β-galactosidase, tissue damage and oxidative stress markers. A dose dependent decrease in apoptosis and DNA damage was also observed. Molecular docking studies also support the protective role of geraniol against the arecoline induced toxicity. The results suggest that geraniol is potent in reducing the toxicity induced by arecoline in the third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ) Bg9." @default.
• W2896960889 created "2018-10-26" @default.
• W2896960889 creator A5049568385 @default.
• W2896960889 creator A5067870027 @default.
• W2896960889 creator A5086171145 @default.
• W2896960889 date "2018-11-28" @default.
• W2896960889 modified "2023-09-26" @default.
• W2896960889 title "Effect of geraniol against arecoline induced toxicity in the third instar larvae of transgenic<i>Drosophila melanogaster (hsp70-lacZ) Bg⁹</i>" @default.
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• W2896960889 doi "https://doi.org/10.1080/15376516.2018.1534299" @default.
• W2896960889 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30318983" @default.
• W2896960889 hasPublicationYear "2018" @default.
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