FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896978005> ?p ?o ?g. }

• W2896978005 endingPage "369" @default.
• W2896978005 startingPage "363" @default.
• W2896978005 abstract "Abstract Background: Pancreatic cancer is the third leading cause of cancer-related death in the United States. Total serum cholesterol (TSC) may predict cancer risk, although its role independent of statins remains elusive. We examined the association between TSC and pancreatic cancer risk independent of statins. Methods: A nested case–control analysis was conducted among statin-naïve patients within The Health Improvement Network (THIN), a United Kingdom–based general practice database. Cases were &gt;40 years old and diagnosed with pancreatic cancer after at least 6 months of follow-up. Controls were selected by incidence density sampling and matched by age, sex, practice site, and follow-up. Primary exposure was TSC (mmol/L) prior to index date. Conditional logistic regression estimated ORs for pancreatic cancer risk associated with TSC. Sensitivity analyses were conducted among nondiabetics. Results: Among 1,241 cases and 3,307 matched controls, an average 8% reduction was observed in pancreatic cancer risk per mmol/L increase in TSC [OR 0.92, 95% confidence interval (CI): 0.85–1.00; nondiabetics: OR 0.91, 95% CI: 0.83–0.99]. When TSC was measured at 12-month intervals prior to diagnosis, the OR between TSC and pancreatic cancer was 0.88 at 0 to 12 months (95% CI: 0.77–1.00; nondiabetics: OR 0.81, 95% CI: 0.68–0.96). No significant association was seen at subsequent discrete intervals before index date. Conclusions: TSC is a significant predictor of short-term risk for pancreatic cancer. This risk increase associated with lower TSC was independent of statins. Impact: TSC could serve as a biomarker for risk stratification, screening, and early diagnosis of pancreatic cancer in future clinical prediction models." @default.
• W2896978005 created "2018-10-26" @default.
• W2896978005 creator A5001947506 @default.
• W2896978005 creator A5042304706 @default.
• W2896978005 creator A5046961512 @default.
• W2896978005 creator A5055266545 @default.
• W2896978005 date "2019-02-01" @default.
• W2896978005 modified "2023-10-18" @default.
• W2896978005 title "Total Serum Cholesterol and Pancreatic Cancer: A Nested Case–Control Study" @default.
• W2896978005 cites W1606993997 @default.
• W2896978005 cites W173808884 @default.
• W2896978005 cites W1775522749 @default.
• W2896978005 cites W1951308530 @default.
• W2896978005 cites W1968179943 @default.
• W2896978005 cites W1968812902 @default.
• W2896978005 cites W1978270000 @default.
• W2896978005 cites W1986536619 @default.
• W2896978005 cites W1989375145 @default.
• W2896978005 cites W1994177577 @default.
• W2896978005 cites W1996283446 @default.
• W2896978005 cites W2005592295 @default.
• W2896978005 cites W2017871510 @default.
• W2896978005 cites W2019429246 @default.
• W2896978005 cites W2033654850 @default.
• W2896978005 cites W2033945449 @default.
• W2896978005 cites W2035059839 @default.
• W2896978005 cites W2057022467 @default.
• W2896978005 cites W2060656087 @default.
• W2896978005 cites W2063518057 @default.
• W2896978005 cites W2065975091 @default.
• W2896978005 cites W2069381373 @default.
• W2896978005 cites W2072703569 @default.
• W2896978005 cites W2078533938 @default.
• W2896978005 cites W2079285484 @default.
• W2896978005 cites W2079972032 @default.
• W2896978005 cites W2091350617 @default.
• W2896978005 cites W2100358697 @default.
• W2896978005 cites W2104473949 @default.
• W2896978005 cites W2110307604 @default.
• W2896978005 cites W2111234909 @default.
• W2896978005 cites W2113362613 @default.
• W2896978005 cites W2114164056 @default.
• W2896978005 cites W2116496762 @default.
• W2896978005 cites W2126300254 @default.
• W2896978005 cites W2136383161 @default.
• W2896978005 cites W2142527465 @default.
• W2896978005 cites W2143132394 @default.
• W2896978005 cites W2145724852 @default.
• W2896978005 cites W2146939000 @default.
• W2896978005 cites W2149847053 @default.
• W2896978005 cites W2152193952 @default.
• W2896978005 cites W2158463173 @default.
• W2896978005 cites W2159946871 @default.
• W2896978005 cites W2161955349 @default.
• W2896978005 cites W2163459778 @default.
• W2896978005 cites W2169214947 @default.
• W2896978005 cites W2202568972 @default.
• W2896978005 cites W2207853819 @default.
• W2896978005 cites W2265830440 @default.
• W2896978005 cites W2293250428 @default.
• W2896978005 cites W2344332711 @default.
• W2896978005 cites W2560633348 @default.
• W2896978005 cites W2564815138 @default.
• W2896978005 cites W3026814848 @default.
• W2896978005 cites W4210976084 @default.
• W2896978005 cites W4229719081 @default.
• W2896978005 doi "https://doi.org/10.1158/1055-9965.epi-18-0421" @default.
• W2896978005 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30333217" @default.
• W2896978005 hasPublicationYear "2019" @default.
• W2896978005 type Work @default.
• W2896978005 sameAs 2896978005 @default.
• W2896978005 citedByCount "21" @default.
• W2896978005 countsByYear W28969780052019 @default.
• W2896978005 countsByYear W28969780052020 @default.
• W2896978005 countsByYear W28969780052021 @default.
• W2896978005 countsByYear W28969780052022 @default.
• W2896978005 countsByYear W28969780052023 @default.
• W2896978005 crossrefType "journal-article" @default.
• W2896978005 hasAuthorship W2896978005A5001947506 @default.
• W2896978005 hasAuthorship W2896978005A5042304706 @default.
• W2896978005 hasAuthorship W2896978005A5046961512 @default.
• W2896978005 hasAuthorship W2896978005A5055266545 @default.
• W2896978005 hasConcept C120665830 @default.
• W2896978005 hasConcept C121332964 @default.
• W2896978005 hasConcept C121608353 @default.
• W2896978005 hasConcept C126322002 @default.
• W2896978005 hasConcept C146304588 @default.
• W2896978005 hasConcept C151956035 @default.
• W2896978005 hasConcept C165617652 @default.
• W2896978005 hasConcept C2779662715 @default.
• W2896978005 hasConcept C2780210213 @default.
• W2896978005 hasConcept C44249647 @default.
• W2896978005 hasConcept C50440223 @default.
• W2896978005 hasConcept C61511704 @default.
• W2896978005 hasConcept C71924100 @default.
• W2896978005 hasConcept C90924648 @default.
• W2896978005 hasConceptScore W2896978005C120665830 @default.
• W2896978005 hasConceptScore W2896978005C121332964 @default.

• next