Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896980868> ?p ?o ?g. }
- W2896980868 endingPage "6909" @default.
- W2896980868 startingPage "6901" @default.
- W2896980868 abstract "Vascular normalization is a new concept of targeting angiogenesis to restore vessel structure and function and to increase blood perfusion and delivery of drugs. It has been confirmed that vascular normalization can decrease relapse and benefit other cancer therapy, including chemotherapy, radiotherapy, and immune cell therapy. The key point of this therapy is to inhibit pro-angiogenic factors and make it be balanced with anti-angiogenic factors, resulting in a mature and normal vessel characteristic. Vascular endothelial growth factor (VEGF) is a key player in the process of tumor angiogenesis, and inhibiting VEGF is a primary approach to tumor vessel normalization. Herein, we review newly uncovered mechanisms governing angiogenesis and vascular normalization of cancer and place emphasis on targeting VEGF pathway to normalize the vasculature. Also, important methods to depress VEGF pathway and make tumor vascular are discussed." @default.
- W2896980868 created "2018-10-26" @default.
- W2896980868 creator A5002325550 @default.
- W2896980868 creator A5019119910 @default.
- W2896980868 creator A5055376209 @default.
- W2896980868 date "2018-10-01" @default.
- W2896980868 modified "2023-10-17" @default.
- W2896980868 title "Targeting VEGF pathway to normalize the vasculature: an emerging insight in cancer therapy" @default.
- W2896980868 cites W1488835155 @default.
- W2896980868 cites W1524688066 @default.
- W2896980868 cites W1603230122 @default.
- W2896980868 cites W1611419331 @default.
- W2896980868 cites W1647075334 @default.
- W2896980868 cites W1807482481 @default.
- W2896980868 cites W1810166418 @default.
- W2896980868 cites W1830858249 @default.
- W2896980868 cites W1917630072 @default.
- W2896980868 cites W1964823689 @default.
- W2896980868 cites W1967194906 @default.
- W2896980868 cites W1969328947 @default.
- W2896980868 cites W1970578871 @default.
- W2896980868 cites W1976221241 @default.
- W2896980868 cites W1977887541 @default.
- W2896980868 cites W1978139448 @default.
- W2896980868 cites W1981182976 @default.
- W2896980868 cites W1983763042 @default.
- W2896980868 cites W1983953288 @default.
- W2896980868 cites W1985858988 @default.
- W2896980868 cites W1990983926 @default.
- W2896980868 cites W1992049575 @default.
- W2896980868 cites W2000584529 @default.
- W2896980868 cites W2002923380 @default.
- W2896980868 cites W2004941068 @default.
- W2896980868 cites W2006202974 @default.
- W2896980868 cites W2007142119 @default.
- W2896980868 cites W2007897471 @default.
- W2896980868 cites W2009821528 @default.
- W2896980868 cites W2010402627 @default.
- W2896980868 cites W2014896540 @default.
- W2896980868 cites W2017322644 @default.
- W2896980868 cites W2017358009 @default.
- W2896980868 cites W2019367792 @default.
- W2896980868 cites W2021052565 @default.
- W2896980868 cites W2021529165 @default.
- W2896980868 cites W2023064334 @default.
- W2896980868 cites W2023572006 @default.
- W2896980868 cites W2024206845 @default.
- W2896980868 cites W2027011993 @default.
- W2896980868 cites W2035615893 @default.
- W2896980868 cites W2039893214 @default.
- W2896980868 cites W2041884448 @default.
- W2896980868 cites W2042540245 @default.
- W2896980868 cites W2045247659 @default.
- W2896980868 cites W2053702192 @default.
- W2896980868 cites W2059276027 @default.
- W2896980868 cites W2062594120 @default.
- W2896980868 cites W2065863629 @default.
- W2896980868 cites W2069759108 @default.
- W2896980868 cites W2070800535 @default.
- W2896980868 cites W2073470348 @default.
- W2896980868 cites W2077129920 @default.
- W2896980868 cites W2080132341 @default.
- W2896980868 cites W2081107312 @default.
- W2896980868 cites W2086797785 @default.
- W2896980868 cites W2092440654 @default.
- W2896980868 cites W2092930138 @default.
- W2896980868 cites W2093216555 @default.
- W2896980868 cites W2094803864 @default.
- W2896980868 cites W2098176107 @default.
- W2896980868 cites W2104300873 @default.
- W2896980868 cites W2109134893 @default.
- W2896980868 cites W2112747018 @default.
- W2896980868 cites W2115162283 @default.
- W2896980868 cites W2115852392 @default.
- W2896980868 cites W2116401711 @default.
- W2896980868 cites W2117530284 @default.
- W2896980868 cites W2117713501 @default.
- W2896980868 cites W2126163864 @default.
- W2896980868 cites W2127832422 @default.
- W2896980868 cites W2129994868 @default.
- W2896980868 cites W2131153559 @default.
- W2896980868 cites W2132416992 @default.
- W2896980868 cites W2137373982 @default.
- W2896980868 cites W2137738448 @default.
- W2896980868 cites W2140570135 @default.
- W2896980868 cites W2142237270 @default.
- W2896980868 cites W2142644858 @default.
- W2896980868 cites W2143842256 @default.
- W2896980868 cites W2148216490 @default.
- W2896980868 cites W2153297361 @default.
- W2896980868 cites W2153726078 @default.
- W2896980868 cites W2161312917 @default.
- W2896980868 cites W2163294226 @default.
- W2896980868 cites W2164971856 @default.
- W2896980868 cites W2166005447 @default.
- W2896980868 cites W2166797651 @default.
- W2896980868 cites W2231303906 @default.
- W2896980868 cites W2264671620 @default.