Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896983106> ?p ?o ?g. }
- W2896983106 endingPage "341" @default.
- W2896983106 startingPage "332" @default.
- W2896983106 abstract "The majority of patients with hepatocellular carcinoma (HCC) present with advanced disease. While first-line therapy with sorafenib is considered standard of care for patients with advancedHCC, outcomes remain poor. Despite early evidence of antitumor activity from Phase II trials of multiple other tyrosine kinase inhibitors, Phase III trials have largely failed to show an improvement insurvival outcomes over sorafenib. Given the encouraging early results with liver-directed radiotherapy for patients with advanced HCC, there is an increased interest in combination of these therapies tooptimize patient outcomes and improve survival by maximizing both local and distant disease control. Phase II trials of checkpoint inhibitors in HCC have also reported encouraging results, and Phase IIItrials are ongoing. Trials of combining radiotherapy with immunotherapy in solid tumors have shown intriguing results, potentially reflecting the opportunity for synergistic effects with the use of both modalities." @default.
- W2896983106 created "2018-10-26" @default.
- W2896983106 creator A5044225007 @default.
- W2896983106 creator A5070093254 @default.
- W2896983106 creator A5088566246 @default.
- W2896983106 date "2018-10-01" @default.
- W2896983106 modified "2023-09-23" @default.
- W2896983106 title "Evolving Systemic Therapy in Hepatocellular Carcinoma: Current Management and Opportunities for Integration With Radiotherapy" @default.
- W2896983106 cites W1523531791 @default.
- W2896983106 cites W1965309017 @default.
- W2896983106 cites W1971837077 @default.
- W2896983106 cites W1988684186 @default.
- W2896983106 cites W1990303771 @default.
- W2896983106 cites W1992253423 @default.
- W2896983106 cites W1994193851 @default.
- W2896983106 cites W2015472953 @default.
- W2896983106 cites W2022059412 @default.
- W2896983106 cites W2029029081 @default.
- W2896983106 cites W2029336551 @default.
- W2896983106 cites W2032166347 @default.
- W2896983106 cites W2036418044 @default.
- W2896983106 cites W2046000826 @default.
- W2896983106 cites W2051684210 @default.
- W2896983106 cites W2052730188 @default.
- W2896983106 cites W2058887247 @default.
- W2896983106 cites W2069723381 @default.
- W2896983106 cites W2104721463 @default.
- W2896983106 cites W2106036268 @default.
- W2896983106 cites W2114029473 @default.
- W2896983106 cites W2115497785 @default.
- W2896983106 cites W2119242310 @default.
- W2896983106 cites W2119442895 @default.
- W2896983106 cites W2120967735 @default.
- W2896983106 cites W2122044186 @default.
- W2896983106 cites W2127098527 @default.
- W2896983106 cites W2128965737 @default.
- W2896983106 cites W2141314162 @default.
- W2896983106 cites W2158207366 @default.
- W2896983106 cites W2165901246 @default.
- W2896983106 cites W2166662937 @default.
- W2896983106 cites W2218507773 @default.
- W2896983106 cites W2221304580 @default.
- W2896983106 cites W2495512985 @default.
- W2896983106 cites W2502891277 @default.
- W2896983106 cites W2546700240 @default.
- W2896983106 cites W2560499218 @default.
- W2896983106 cites W2580579569 @default.
- W2896983106 cites W2588718083 @default.
- W2896983106 cites W2599322403 @default.
- W2896983106 cites W2606311670 @default.
- W2896983106 cites W2606367731 @default.
- W2896983106 cites W2624275086 @default.
- W2896983106 cites W2752251204 @default.
- W2896983106 cites W2753432434 @default.
- W2896983106 cites W2759382352 @default.
- W2896983106 cites W2765356289 @default.
- W2896983106 cites W2787358630 @default.
- W2896983106 cites W2787553571 @default.
- W2896983106 cites W4229822810 @default.
- W2896983106 cites W4242397533 @default.
- W2896983106 cites W4245403358 @default.
- W2896983106 doi "https://doi.org/10.1016/j.semradonc.2018.06.006" @default.
- W2896983106 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30309643" @default.
- W2896983106 hasPublicationYear "2018" @default.
- W2896983106 type Work @default.
- W2896983106 sameAs 2896983106 @default.
- W2896983106 citedByCount "12" @default.
- W2896983106 countsByYear W28969831062019 @default.
- W2896983106 countsByYear W28969831062020 @default.
- W2896983106 countsByYear W28969831062021 @default.
- W2896983106 countsByYear W28969831062022 @default.
- W2896983106 crossrefType "journal-article" @default.
- W2896983106 hasAuthorship W2896983106A5044225007 @default.
- W2896983106 hasAuthorship W2896983106A5070093254 @default.
- W2896983106 hasAuthorship W2896983106A5088566246 @default.
- W2896983106 hasConcept C121608353 @default.
- W2896983106 hasConcept C126322002 @default.
- W2896983106 hasConcept C143998085 @default.
- W2896983106 hasConcept C177713679 @default.
- W2896983106 hasConcept C185926286 @default.
- W2896983106 hasConcept C2777701055 @default.
- W2896983106 hasConcept C2778019345 @default.
- W2896983106 hasConcept C2778695046 @default.
- W2896983106 hasConcept C2779134260 @default.
- W2896983106 hasConcept C2993769353 @default.
- W2896983106 hasConcept C509974204 @default.
- W2896983106 hasConcept C530470458 @default.
- W2896983106 hasConcept C535046627 @default.
- W2896983106 hasConcept C71924100 @default.
- W2896983106 hasConceptScore W2896983106C121608353 @default.
- W2896983106 hasConceptScore W2896983106C126322002 @default.
- W2896983106 hasConceptScore W2896983106C143998085 @default.
- W2896983106 hasConceptScore W2896983106C177713679 @default.
- W2896983106 hasConceptScore W2896983106C185926286 @default.
- W2896983106 hasConceptScore W2896983106C2777701055 @default.
- W2896983106 hasConceptScore W2896983106C2778019345 @default.
- W2896983106 hasConceptScore W2896983106C2778695046 @default.
- W2896983106 hasConceptScore W2896983106C2779134260 @default.