FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896986703> ?p ?o ?g. }

• W2896986703 endingPage "58" @default.
• W2896986703 startingPage "52" @default.
• W2896986703 abstract "Aim. To investigate the connection between the levels of human umbilical cord blood hemopoietic tissue (UCB HT) cryosensitivity (using of the granulocyte-macrophage progenitors (GMPs) percentage loss) and activity of prooxidant processes in whole blood before the beginning of its cryopreservation.Methods of research. Cryopreservation of UCB nuclear cell fraction was carried out by slow freezing under protection of the dimethyl sulfoxide in 5% final concentration (v/v). The loss of GMPs was determined by the difference in the total content of colonies and clusters prior to cryopreservation and after thawing the sample in a short-term tissue culture. The activity of prooxidant processes in UCB was studied by biochemical markers of lipid peroxidation products (LPO) using a spectrophotometric method for determining the concentrations of such products as substrates for lipid peroxidation (isolated double bonds - IDB), intermediate (conjugated dienes (CD), conjugated trienes (CT), conjugated oxodienes (COD)) and final LPO products such as Schiff bases (ShB) for neutral lipids and phospholipids. Data analysis performed on models of analytical groups, regression analysis, mutual conjugation.Results. It has been demonstrated that the level of UCB HT cryosensitivity (due to loss of GMPs) has direct correlation with LPO activity indices (from medium to high significance level). The relative risk (RR) of loss of GMPs is significantly increased under the condition of high levels of LPO phospholipid peroxidation in UCB before beginning cryopreservation. In particular, in the case of phospholipid peroxidation, it is: for IDB - RR = 5.29; 95% CI: 2.69-10.38; p <0.001; CD - RR = 5.73; 95% CI: 2.88-11.40; p <0.001; CT and COD - RR = 2.81; 95% CI: 1.72-4.60; p <0.001; ShB - RR = 1, 92, 95% CI: 1.16-3.18, p <0.01, respectively.Conclusions. Evaluation of the activity level of prooxidant processes in UCB using the biochemical markers before the start of the freezing procedure is valuable because of the possibility of creating an early prediction of the HT cryosensitivity, which can be useful in choosing cryopreservation tactics" @default.
• W2896986703 created "2018-10-26" @default.
• W2896986703 creator A5053183002 @default.
• W2896986703 date "2018-07-19" @default.
• W2896986703 modified "2023-09-25" @default.
• W2896986703 title "Prognostic assessment of cryosensitivity level for umbilical cord blood hemopoietic tissue with the help of markers of prooxidant activity processes" @default.
• W2896986703 cites W1906638117 @default.
• W2896986703 cites W1985675880 @default.
• W2896986703 cites W1990089631 @default.
• W2896986703 cites W1999891390 @default.
• W2896986703 cites W2003649512 @default.
• W2896986703 cites W2013679409 @default.
• W2896986703 cites W2079339237 @default.
• W2896986703 cites W2086851581 @default.
• W2896986703 cites W2111255161 @default.
• W2896986703 cites W2123284794 @default.
• W2896986703 cites W2146179723 @default.
• W2896986703 cites W2151327771 @default.
• W2896986703 cites W2155403628 @default.
• W2896986703 cites W2160666689 @default.
• W2896986703 cites W2276882250 @default.
• W2896986703 cites W2284574660 @default.
• W2896986703 cites W2400160024 @default.
• W2896986703 cites W2603317104 @default.
• W2896986703 cites W2782325848 @default.
• W2896986703 cites W2792557306 @default.
• W2896986703 cites W2915060027 @default.
• W2896986703 cites W971208542 @default.
• W2896986703 doi "https://doi.org/10.15587/2519-4798.2018.138222" @default.
• W2896986703 hasPublicationYear "2018" @default.
• W2896986703 type Work @default.
• W2896986703 sameAs 2896986703 @default.
• W2896986703 citedByCount "1" @default.
• W2896986703 countsByYear W28969867032021 @default.
• W2896986703 crossrefType "journal-article" @default.
• W2896986703 hasAuthorship W2896986703A5053183002 @default.
• W2896986703 hasBestOaLocation W28969867031 @default.
• W2896986703 hasConcept C109159458 @default.
• W2896986703 hasConcept C16685009 @default.
• W2896986703 hasConcept C179933525 @default.
• W2896986703 hasConcept C185592680 @default.
• W2896986703 hasConcept C196843134 @default.
• W2896986703 hasConcept C203014093 @default.
• W2896986703 hasConcept C2776955114 @default.
• W2896986703 hasConcept C2778004101 @default.
• W2896986703 hasConcept C2778918659 @default.
• W2896986703 hasConcept C2780829032 @default.
• W2896986703 hasConcept C28328180 @default.
• W2896986703 hasConcept C41625074 @default.
• W2896986703 hasConcept C54355233 @default.
• W2896986703 hasConcept C55493867 @default.
• W2896986703 hasConcept C71924100 @default.
• W2896986703 hasConcept C86803240 @default.
• W2896986703 hasConcept C95444343 @default.
• W2896986703 hasConceptScore W2896986703C109159458 @default.
• W2896986703 hasConceptScore W2896986703C16685009 @default.
• W2896986703 hasConceptScore W2896986703C179933525 @default.
• W2896986703 hasConceptScore W2896986703C185592680 @default.
• W2896986703 hasConceptScore W2896986703C196843134 @default.
• W2896986703 hasConceptScore W2896986703C203014093 @default.
• W2896986703 hasConceptScore W2896986703C2776955114 @default.
• W2896986703 hasConceptScore W2896986703C2778004101 @default.
• W2896986703 hasConceptScore W2896986703C2778918659 @default.
• W2896986703 hasConceptScore W2896986703C2780829032 @default.
• W2896986703 hasConceptScore W2896986703C28328180 @default.
• W2896986703 hasConceptScore W2896986703C41625074 @default.
• W2896986703 hasConceptScore W2896986703C54355233 @default.
• W2896986703 hasConceptScore W2896986703C55493867 @default.
• W2896986703 hasConceptScore W2896986703C71924100 @default.
• W2896986703 hasConceptScore W2896986703C86803240 @default.
• W2896986703 hasConceptScore W2896986703C95444343 @default.
• W2896986703 hasIssue "5 (25)" @default.
• W2896986703 hasLocation W28969867031 @default.
• W2896986703 hasLocation W28969867032 @default.
• W2896986703 hasLocation W28969867033 @default.
• W2896986703 hasOpenAccess W2896986703 @default.
• W2896986703 hasPrimaryLocation W28969867031 @default.
• W2896986703 hasRelatedWork W1994078500 @default.
• W2896986703 hasRelatedWork W2034721324 @default.
• W2896986703 hasRelatedWork W2042069691 @default.
• W2896986703 hasRelatedWork W2045197007 @default.
• W2896986703 hasRelatedWork W2146179401 @default.
• W2896986703 hasRelatedWork W2360708198 @default.
• W2896986703 hasRelatedWork W2363972474 @default.
• W2896986703 hasRelatedWork W2370705668 @default.
• W2896986703 hasRelatedWork W2371272552 @default.
• W2896986703 hasRelatedWork W4313414761 @default.
• W2896986703 hasVolume "0" @default.
• W2896986703 isParatext "false" @default.
• W2896986703 isRetracted "false" @default.
• W2896986703 magId "2896986703" @default.
• W2896986703 workType "article" @default.