FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2896986972> ?p ?o ?g. }

• W2896986972 endingPage "18" @default.
• W2896986972 startingPage "10" @default.
• W2896986972 abstract "Although stem cell transplantation has beneficial effects on tissue regeneration, but there are still problems such as high cost and safety issues. Since stem cell therapy is largely dependent on paracrine activity, in this study, utilization of transplantation of bone marrow stromal cells (BMSCs)-secretome instead of the cells, into damaged ovaries was evaluated to overcome the limitations of stem cell transplantation.In this experimental study, BMSCs were cultured and 25-fold concentrated conditioned medium (CM) from BMSCs was prepared. Female rats were injected intraperitoneally with cyclophosphamide (CTX) for 14 days. Then, BMSCs and CM were individually transplanted into bilateral ovaries, and the ovaries were excised after four weeks of treatment. The follicle count was performed using hematoxylin and eosin (H and E) staining and the apoptotic cells were counted using TUNEL assay. Ovarian function was evaluated by monitoring the ability of ovulation and the levels of serum estradiol (E2) and follicle-stimulating hormone (FSH).Evaluation of the ovarian function and structure showed that results of secretome transplantation were almost similar to those of BMSCs transplantation and there was no significant differences between them.BMSCs-secretome is likely responsible for the therapeutic paracrine effect of BMSCs. Stem cellsecretome is expected to overcome the limitations of stem cell transplantation and become the basis of a novel therapy for ovarian damage." @default.
• W2896986972 created "2018-10-26" @default.
• W2896986972 creator A5011146491 @default.
• W2896986972 creator A5027407059 @default.
• W2896986972 creator A5031663765 @default.
• W2896986972 creator A5036055019 @default.
• W2896986972 creator A5079461805 @default.
• W2896986972 creator A5089691859 @default.
• W2896986972 creator A5091793000 @default.
• W2896986972 date "2018-04-01" @default.
• W2896986972 modified "2023-09-23" @default.
• W2896986972 title "Effect of Transplantation of Bone Marrow Stromal Cell- Conditioned Medium on Ovarian Function, Morphology and Cell Death in Cyclophosphamide-Treated Rats." @default.
• W2896986972 cites W1983663906 @default.
• W2896986972 cites W1989256430 @default.
• W2896986972 cites W1992723596 @default.
• W2896986972 cites W1992913076 @default.
• W2896986972 cites W1995323769 @default.
• W2896986972 cites W2000208654 @default.
• W2896986972 cites W2005943573 @default.
• W2896986972 cites W2008576239 @default.
• W2896986972 cites W2013425827 @default.
• W2896986972 cites W2015215491 @default.
• W2896986972 cites W2017655153 @default.
• W2896986972 cites W2036061724 @default.
• W2896986972 cites W2042379428 @default.
• W2896986972 cites W2043148659 @default.
• W2896986972 cites W2047457187 @default.
• W2896986972 cites W2048270850 @default.
• W2896986972 cites W2050096178 @default.
• W2896986972 cites W2081100505 @default.
• W2896986972 cites W2082909405 @default.
• W2896986972 cites W2085554170 @default.
• W2896986972 cites W2095566284 @default.
• W2896986972 cites W2104136026 @default.
• W2896986972 cites W2135416519 @default.
• W2896986972 cites W2135743018 @default.
• W2896986972 cites W2148028300 @default.
• W2896986972 cites W2154397232 @default.
• W2896986972 cites W2165735772 @default.
• W2896986972 cites W2168426417 @default.
• W2896986972 cites W2193236904 @default.
• W2896986972 cites W2301597926 @default.
• W2896986972 cites W2308102273 @default.
• W2896986972 cites W2328212469 @default.
• W2896986972 cites W2381646039 @default.
• W2896986972 cites W2414056075 @default.
• W2896986972 cites W2461418525 @default.
• W2896986972 cites W2466973740 @default.
• W2896986972 cites W2513880428 @default.
• W2896986972 cites W2537197455 @default.
• W2896986972 cites W274009491 @default.
• W2896986972 doi "https://doi.org/10.22074/cellj.2018.4919" @default.
• W2896986972 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5759671" @default.
• W2896986972 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29308613" @default.
• W2896986972 hasPublicationYear "2018" @default.
• W2896986972 type Work @default.
• W2896986972 sameAs 2896986972 @default.
• W2896986972 citedByCount "6" @default.
• W2896986972 countsByYear W28969869722018 @default.
• W2896986972 countsByYear W28969869722021 @default.
• W2896986972 countsByYear W28969869722022 @default.
• W2896986972 crossrefType "journal-article" @default.
• W2896986972 hasAuthorship W2896986972A5011146491 @default.
• W2896986972 hasAuthorship W2896986972A5027407059 @default.
• W2896986972 hasAuthorship W2896986972A5031663765 @default.
• W2896986972 hasAuthorship W2896986972A5036055019 @default.
• W2896986972 hasAuthorship W2896986972A5079461805 @default.
• W2896986972 hasAuthorship W2896986972A5089691859 @default.
• W2896986972 hasAuthorship W2896986972A5091793000 @default.
• W2896986972 hasConcept C126322002 @default.
• W2896986972 hasConcept C134018914 @default.
• W2896986972 hasConcept C16685009 @default.
• W2896986972 hasConcept C16930146 @default.
• W2896986972 hasConcept C170493617 @default.
• W2896986972 hasConcept C203014093 @default.
• W2896986972 hasConcept C2780007613 @default.
• W2896986972 hasConcept C28328180 @default.
• W2896986972 hasConcept C2911091166 @default.
• W2896986972 hasConcept C502942594 @default.
• W2896986972 hasConcept C55493867 @default.
• W2896986972 hasConcept C71924100 @default.
• W2896986972 hasConcept C7876069 @default.
• W2896986972 hasConcept C86803240 @default.
• W2896986972 hasConcept C95444343 @default.
• W2896986972 hasConceptScore W2896986972C126322002 @default.
• W2896986972 hasConceptScore W2896986972C134018914 @default.
• W2896986972 hasConceptScore W2896986972C16685009 @default.
• W2896986972 hasConceptScore W2896986972C16930146 @default.
• W2896986972 hasConceptScore W2896986972C170493617 @default.
• W2896986972 hasConceptScore W2896986972C203014093 @default.
• W2896986972 hasConceptScore W2896986972C2780007613 @default.
• W2896986972 hasConceptScore W2896986972C28328180 @default.
• W2896986972 hasConceptScore W2896986972C2911091166 @default.
• W2896986972 hasConceptScore W2896986972C502942594 @default.
• W2896986972 hasConceptScore W2896986972C55493867 @default.
• W2896986972 hasConceptScore W2896986972C71924100 @default.
• W2896986972 hasConceptScore W2896986972C7876069 @default.
• W2896986972 hasConceptScore W2896986972C86803240 @default.

• next